While the Internet continued to be used for important reference and record keeping purposes, its power as a communications medium was perhaps most evident by the websites being set up to help those wo
Ever since receiving FDA approval for Aredia in September 1998 Novartis has held the gold standard treatment for bone metastases. In Zometa the Swiss pharmaceutical company possesses a more potent, ne
The considerable investment and overheads required for the development of new drugs mean that pharmaceutical companies must establish brand loyalty throughout a productâ€™s lifecycle in order to protect
Physicians, patients and even healthcare companies were equally well catered for by a number of important eHealth announcements that came to light in the past fortnight. The prospect of remote medical
The growth of outsourced clinical research for the pharmaceutical industry appears to know no bounds, the latest expansion of a pharmiweb client happened in early February when ICON, the global clinic
In anticipation of the launch of Forteo, LeadDiscovery in collaboration with field-leader, Cees Vermeer have produced a state of the art report on both the field of osteoprosis in general and also mor
According to all pharmaceutical regulatory authorities of note, the regulations that apply to offline sales and marketing activity in the industry should also apply to all such activity in the online
With the recent patent expiry of Claritin, a drug that netted Schering-Plough some $5 billion in sales in 2001-2002, the antihistamine market will soon be flooded by a raft of cheap generic copies of
Benign prostatic hypertrophy (BPH) is very common in men aged 50 years and older. Resultant bladder hyperactivity leads to self-enforced changes in life style, increased frequency of falls in the immo
With over $6 billion in sales in 2002, COX-II inhibitors are dominating the market for NSAIDs at a global level. These drugs have however, struggled to make an impact outside the US. With their long-t
In rheumatoid arthritis treatment a shift towards the earlier use of DMARDs has threatened the dominance of the NSAID class of drugs. This has opened up considerable opportunity for drugs such as Remi
Would you do a clinical study in Spain? The immediate reaction of the majority of the international clinical research community is â€śmaybe but only at the later stages (Phase III-b, Phase IV)â€ť. Spain i
Due to the high incidence of migraine and its effect on quality of life the highly competitive triptan market exceeds of $2 billion in global sales. Triptans aborting a migraine attack once it has sta
Retinoids play a key role in differentiation, proliferation and apoptosis. As a result over 30 analogs of retinoic acid are now either in development or on the market. Retinoids in current use are eff
The proposed merger between Pfizer and Pharmacia will create a company with total ethical sales twice those of its nearest competitor. Declining R&D productivity, and a flood of patent expirations hav
The process of finding, screening, and recruiting clinical trial patients at multiple research sites is a challenge for even the largest pharmaceutical sponsors and clinical research organizations.
Dr Faiz Kermani
The growing number of ePrescribing, health information and other technological initiatives mean that IT is becoming an ever more important and integral part of the healthcare system, for doctors and p
Ever since it first came to market in 1993, the anticonvulsant drug Neurontin has consistently been one of Pfizer's top earners, generating considerable sales and driving strong growth for the New Yor
The pharmaceutical industryâ€™s expectations for increasing revenue rely to a large extent on ensuring that their heavy R&D investment translates into new drugs. In 2000, the global pharmaceutical indu
High-dose therapy for multiple myeloma is effective in increasing median survival, but is severely toxic, limiting its use. In addition, all patients eventually relapse and suffer disease progression.
The pharmaceutical industry, much of which dreams of having the marketing agility of a primitive vertebrate, has found a sales-promotion tool that sometimes works in the United States and New Zealand.
It is now well established that cellular suicide (apoptosis or programmed cell death) is central to a number of physiological cellular processes and is essential in the maintenance of homeostasis and
Dr Jon Goldhill
The past fortnight saw a number of eHealth developments. Patients and consumer groups were particularly well catered for with the launch of important new cancer, diabetes, back pain, STD, substance ab
The pharmaceutical industry has a wide range of roles for medics, from clinical pharmacology where the clinical care of study subjects is your responsibility, to the position of medical adviser, which
Biopharmaceutical companies face numerous challenges to boost their output of new chemical entities and to strengthen their product pipelines. In order to remain profitable and competitive, they have
Non-compliance is the failure of patients to take medicines in their prescribed manner. Patient non-compliance is a serious healthcare issue, with studies showing that it can range from 20% to 80% dep
Four major brands, TAPâ€™s Lupron, AstraZenecaâ€™s Zoladex, Nolvadex and Casodex, account for 49% of the total value of the anti-hormonals market at present. The loss of patent protection for these compou
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