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Features
Pharma NewsBytes: Selected pharma press releases - Dec 1st-17th

18 Dec 03

Pharma NewsBytes selects out what LeadDiscovery considers as being some of the most interesting press releases to have appeared on their DailyUpdates tracking service over the past few weeks. Currently featured new items focus on development activity in the field of Alzheimer's disease; advances in autoimmune diseases and inflammatory disorders; and news from the 26th Annual San Antonio Breast Cancer Symposium
LeadDiscovery

Janus tyrosine kinase 3 inhibition for the prevention of transplant rejection

18 Dec 03

Transplantation immunotherapy commonly involves the use of azathioprine often combined with low doses of cyclosporine. Increased susceptibility to infection and severe toxicity represent serious adverse effects and a newer molecular target being investigated for the prevention of transplant rejection is Janus tyrosine kinase 3 (Jak3). Jak3 is this months "Target of the Month" from LeadDiscovery's and here they describe Pfizer's efforts to optimize inhibitors of this kinase
LeadDiscovery

Interviews and your personality report

16 Dec 03

Personality test experts People Maps return to offer candidates more invaluable advise about the use of personality profilers and their importance in the job interview process
Martin Gibbons

How to | Cope with Redundancy

16 Dec 03

Redundancy – meaning a position of employment is no longer tenable – is a traumatic experience. It is possibly one of the most devastating events you’ll have to go through in your career but one that is becoming all too frequent across the industry.
Aileen Parlane

Best Practices for Medical Science Liaisons

15 Dec 03

This comprehensive one-day training offers MSLs, their managers and those interested in a better understanding of the profession an overview of what the job entails, best practices and realistic ways to incorporate them into your own job. The training will focus on the components of a successful career as a MSL, as opposed to educating on individual therapeutic types.
Jennifer McGinnis

Global Clinical Supplies

15 Dec 03

Increased regulations and review are continually challenging clinical supply operations. In addition, managing diverse resources while ensuring accurate, timely supply of materials is always difficult. Pharmaceutical Education Associates “Global Clinical Supplies” conference will show you the key strategies you’ll need to ensure efficiency and compliance in your global supply operations.
Jennifer McGinnis

Emerging Drug Discovery Targets

21 Nov 03

This edition of "Emerging Drug Discovery Targets" features a potent histone deacetylase inhibitor from Norvartis for the treatment of cancer, two new approaches to metabolic disorders and VEGFR-1 as a target for rheumatoid arthritis. As usual we also provide updates on industrial advances and licensing opportunities.
LeadDiscovery

NVP-LAQ824 a novel histone deacetylase inhibitor

19 Nov 03

The field of histone deacetylation continues to receive considerable interest principally due to the ability of histone deacetylase (HDAC) inhibitors to produce cytostatic activity in cancer, but more recently due to the role that this class has in other indications such as autoimmune disorders. Novartis researchers have now developed a HDAC inhibitor of greater anti-proliferative potency than that of SAHA, and which almost completely blocked the growth of human colon and lung cancer xenografts
LeadDiscovery

Pharma NewsBytes: Oct 27nd- Nov 17th

19 Nov 03

Pharma NewsBytes selects out what we consider as being some of the most interesting press releases to have appeared on our DailyUpdates tracking service over the past few weeks. Currently featured new items focus on development activity in the field of rheumatoid arthritis; advances in anti-hyperlipemia therapeutics; and the termination of MK-0869 development for the treatment of depression
LeadDiscovery

Rheumatoid arthritis: Emerging drug discovery targets and therapeutic candidates

04 Nov 03

It is predicted that the annual value of the market for drugs used to treat autoimmune disease will exceed $20 billion in the next few years. Rheumatoid arthritis is one of the more common and difficult to treat autoimmune diseases and there is a great deal of interest in the discovery of novel drugs to treat this condition. This comprehensive report evaluates breaking drug discovery targets and therapeutic candidates for the treatment of this disease
LeadDiscovery

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