Seafood ID from ACGT, Inc., is dedicated to the use of DNA testing to identify or prevent seafood mislabeling. Towards that goal, ACGT, Inc. has chosen to clarify their position on a crucial subject - the use of appropriate DNA databases to identify seafood species. At issue is the use of proprietary DNA databases versus those in the public domain, including GenBank (administered by the National Center for Biotechnology Information), the Barcode of Life Database (BOLD), and the database produced by the FDA in the course of their own research (found at http://www.fda.gov/Food/FoodSafety/Product-SpecificInformation/Seafood/DNAspeciation/ucm238880.htm).
Seafood ID from ACGT, Inc. does not use proprietary databases that are, by definition, privately owned. The data in proprietary databases is not open to inspection or evaluation by outside experts including scientists at the FDA.
The FDA allows the use of public databases as long as the users have the scientific expertise required to make judgments about sequence information in those databases. All data analysis at Seafood ID from ACGT, Inc. is performed by Ph.D. level investigators, and the interpretation of the results is verified. In addition to using public databases to determine seafood species, ACGT, Inc. uses them every day to aid pharmaceutical, biotechnology and government scientists in the fight against diseases which include cancer, diabetes, and heart disease.
While a proprietary database is not reviewable, public databases are – and are self-correcting. Scientists publish DNA sequence data until a “consensus sequence” is obtained. The consensus sequence is the one used by Seafood ID from ACGT, Inc. Public databases contain both sequences from peer-reviewed journal publications and un-reviewed sequences from DNA analysis laboratories all over the world, and some species have hundreds or even thousands of sequences in the same database.
“If a client wants us to test a species and the only DNA sequence data is in GenBank and it all comes from the same laboratory and none of it is in a journal, that client gets a call saying that we can’t do the project,” according to Edward E. Diehl, Ph.D., Director of Business Development. “Our business is built on science, not the other way around, We have an almost twenty year history of serving clients who are at the pinnacle of scientific and clinical research, and we are proud to bring our expertise to bear on the global seafood mislabeling problem.”
About ACGT, Inc.
ACGT, Inc. was established in 1993 with the goal of providing high-quality DNA sequencing services to the research community. As the demand for DNA sequencing and genomics analysis increased, ACGT, Inc. expanded the range of services it offered while consistently utilizing cutting edge technology to serve its clients. At its current location in Wheeling, IL, ACGT, Inc. continues to deliver high quality scientific results along with excellent customer service and competitive pricing. In addition to our species DNA identification services, ACGT, Inc. offers next generation DNA sequencing, gene expression analysis, cloning, library construction, mutagenesis, genotyping, pharmacogenomics, and genetic stability testing. ACGT, Inc. is CLIA registered and GLP-compliant FDA submission support is available for most projects.
Last updated on: 10/04/2012