Research and Markets (http://www.researchandmarkets.com/research/fn5xl9/pharmaceutical) has announced the addition of the "Pharmaceutical Powder Compaction Technology" book to their offering.
Revised to reflect modern pharmaceutical compacting techniques, this Second Edition explores compaction of powder constituents (both active ingredient and excipients) and guides pharmaceutical engineers, formulation scientists, product development and quality assurance personnel through the compaction formulation process to ensure consistent and reproducible disintegration and dispersion profiles. This unique reference describes the physical structure of pharmaceutical compacts, the bonding phenomena that occur during powder compaction, and the compression mechanisms of pharmaceutical particles.
This updated edition continues to cover the theory and basic principles of powder compaction, but now focuses further on its application, indicating the important parameters for success in small batches and how this process can be migrated into commercial manufacture.
- coverage of compaction data analysis techniques to ensure optimal application in manufacture
- fundamentals of instrumentation for compaction
- compaction functionality testing, which is likely to become a USP requirement
- design space for compaction, an essential consideration for quality by design, and PAT
- the metrics required for scalability in tablet compression and that act as performance indicators in commercial viability
- components of interactive compaction and preformulation database for commonly used excipients to help speed up process considerations and enhance outcomes
Section 1 THEORY OF COMPACTION
1. Intermolecular Bonding Forces: where materials and process come together
Section 2 COMPACTION DATA ANALYSIS TECHNIQUES
2. Viscoelastic Models
3. Application of Percolation Theory and Fractal Geometry to Tablet Compaction
4. Post Compaction Data Analysis Techniques
Section 3 INTRUMENTATION AND EQUIPMENT IN COMPACTION
5. Tablet Press Instrumentation in the Research and Development Environment
6. Advanced Compaction Research Equipment: Compaction Simulators
7. Compactability Functionality Test
Section 4 ROLE OF COMPACTION IN THE FORMULATION AND PROCESS DEVELOPMENT OF TABLETTING
8. Compaction Properties of Directly Compressible Materials
9. Lubrication Issues in Direct Compaction
10. Crystal Engineering and Particle Design for the Powder Compaction Process
11. Compaction of Combination Products
12. Quality by Design and Compression
13. Expert Systems and Their Use in Pharmaceutical Applications
14. Press-To-Press Scalability and Transitioning Factors
For more information visithttp://www.researchandmarkets.com/research/fn5xl9/pharmaceuticalBusiness Wire
Last updated on: 05/10/2012
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