Pharmiweb ChannelsAll | PharmaCo | Clinical Research | R&D/BioTech | Sales/Mktg | Healthcare | Recruitment | Pharmacy | Medical Comms

Pharmiweb.com RSS Feed Pharmiweb.com RSS Feeds

Pharmiweb.com RSS Feed PharmiWeb Candidate Blog

Pharmiweb.com RSS Feed PharmiWeb Client Blog

Advertising

Press Release

Eco-friendly Optics: Spider Silk’s Hidden Talents Brought to Light for Applications in Biosensors, Lasers, Microchips

The Optical Society
Posted on: 11 Oct 12

Spiders use their silk to catch lunch. Now physicists are using it to catch light. New research shows that natural silk could be an eco-friendly alternative to more traditional ways of manipulating light, such as through glass or plastic fiber optic cables. Two teams independently exploring possible applications for the material’s photonic talents will present their latest breakthroughs at the Optical Society's (OSA) Annual Meeting, Frontiers in Optics (FiO) 2012, to be held next week in Rochester, N.Y.

A pristine silk fiber integrated into a photonic chip. The fiber connects three disks that can hold light. During the experiment, light is injected into one of the disks and propagates along the silk to the other two. Image courtesy of Nolwenn Huby.

Biomedical engineer Fiorenzo Omenetto of Tufts University in Boston will discuss his group’s work fabricating concoctions of proteins that make use of silk’s optical properties for implantable sensors and other biology-technology interfaces.

Physicist Nolwenn Huby at the CNRS Institut de Physiques de Rennes in France will talk about her team's use of pristine, natural spider silk to guide light through photonic chips—technology that could give birth to silk-based biosensors and medical imaging devices for use inside the body.

Both groups hope their work will lead to medical advancements that take advantage of the optical properties of silk. One of the strongest fibers in nature (the dragline used by spiders to form the structure of their webs is stronger, pound for pound, than steel), silk is biocompatible, biodegradable, and extremely hardy. Produced naturally by spiders and silkworms, it is a renewable resource. Added to these benefits is the more recent discovery that silk is a gifted manipulator of light, which can travel through silk almost as easily as it flows through glass fibers.

Though it may not be the best material in every one of these categories, the combination of talents is what makes silk such an attractive material to study, Omenetto explains. "There are materials that can do one of each, or a few of each," he says, "but seldom all of each."

Silk-based ‘plastics’ for implantable devices

In their efforts to exploit silk’s optical merits, Omenetto’s team is developing silk-based materials that look like plastic, but retain the optical properties of pristine silk. One of the advantages of these materials is that they can degrade and be reabsorbed by the body. A sensor or tag made of silk protein could be implanted—at the site of a fractured bone, for example, to monitor healing—and merely left to dissolve. Once its purpose had been served, the silk tag would harmlessly fade away.

Omenetto is currently investigating a range of questions, from fundamental to commercial, and they go beyond implantable optics. His team recently won an INSPIRE grant from the National Science Foundation to create electronic components that are compostable. He has developed and tested a blue laser made from silk fiber-doped materials that is not only biodegradable but also uses less power to induce lasing than the acrylic materials that are commonly used. He is also exploring the possibilities of using silk to integrate a technological component with living tissue. "We’re thinking of how to scale up [production], how to interface with current technology," Omenetto says. He hopes some of the more "gadget-like" fruits of his labor will be commercially available within the next five to 10 years.

Guiding light with real silk

Silk-doped composites are the subject of Omenetto's talk at FiO, but the optical merits of pristine silk will be the subject of Huby’s. Her team is experimenting with pure spider silk as a relatively inexpensive and ecologically friendly way to manipulate light within photonic chips.

As a light guide, silk works in a way comparable to the more commonly used glass microfibers that carry light within a chip; but silk comes out of the spider ready to use, whereas glass microfibers have to be heated to high levels and carefully sculpted at great expense. Huby's silk is collected by a group of molecular spectroscopy experts led by Michel Pézolet of Université Laval in Quebec, then integrated into circuits at her team's lab at Rennes. To her knowledge, this is the first time the optical properties of pristine silk have been exploited.

By integrating real spider silk into a microchip, the researchers found that silk could not only propagate light but could also direct light, or "couple" it, to selected parts of the chip. Huby hopes this work can be used to create biosensors that could detect the presence of a molecule or the activity of a protein: as light waves passed through a blood sample, for example, the molecules would change the properties of the light wave in an observable way.

The next step for Huby’s team, she says, is to see what biologists and medical professionals need and then create devices they can use. Besides making biosensors, spider silk could also provide a light source for taking pictures inside of the body. Natural silk is only five microns in diameter, less than a tenth the width of a human hair. A pristine fiber of spider silk, which is so thin and strong, could carry light into the body through a very small opening, providing less invasive ways to do internal imaging or even chemical diagnoses using spectroscopy, which is the analysis of matter based on its interaction with light.

As a spokesman for silk's status as the material of the future—he gave a TED talk on the subject last year—Omenetto believes these recent successes will help more people become excited about the potential of this remarkable material.

"I like to think we threw a big stone in the pond," Omenetto says. "And hopefully the waves will continue."

Both presentations take place Monday, Oct. 15 at the Rochester Riverside Convention Center in Rochester, N.Y. Presentation FM3E.3. “Silk-based Optics and Photonics” by Fiorenzo Omenetto is at 2:30 p.m. followed by presentation FM3E.4 “Optical Propagation and Integration of Pristine Major Ampullate Spider Silk Fibers” by Huby et al. at 3 p.m.

EDITOR’S NOTE: High-resolution images are available to members of the media upon request. Contact Angela Stark, astark@osa.org.

PRESS REGISTRATION: A press room for credentialed press and analysts will be located in the Rochester Riverside Convention Center, Sunday through Thursday, Oct. 14-18. Those interested in obtaining a press badge for FiO should contact OSA's Angela Stark at 202.416.1443 or astark@osa.org. A full list of meeting highlights for press is available on the FiO website.

About the Meeting

Frontiers in Optics (FiO) 2012 is the Optical Society’s (OSA) 96th Annual Meeting and is being held together with Laser Science XXVIII, the annual meeting of the American Physical Society (APS) Division of Laser Science (DLS). The two meetings unite the OSA and APS communities for five days of quality, cutting-edge presentations, fascinating invited speakers and a variety of special events spanning a broad range of topics in optics and photonics—the science of light—across the disciplines of physics, biology and chemistry. FiO 2012 will also offer a number of Short Courses designed to increase participants’ knowledge of a specific subject in the optical sciences while offering the experience of insightful teachers. An exhibit floor featuring leading optics companies will further enhance the meeting. More information at www.FrontiersinOptics.org.

About OSA

Uniting more than 180,000 professionals from 175 countries, the Optical Society (OSA) brings together the global optics community through its programs and initiatives. Since 1916 OSA has worked to advance the common interests of the field, providing educational resources to the scientists, engineers and business leaders who work in the field by promoting the science of light and the advanced technologies made possible by optics and photonics. OSA publications, events, technical groups and programs foster optics knowledge and scientific collaboration among all those with an interest in optics and photonics. For more information, visit www.osa.org.

Photos/Multimedia Gallery Available: http://www.businesswire.com/cgi-bin/mmg.cgi?eid=50438220&lang=en

Business Wire
http://www.businesswire.com/

Last updated on: 11/10/2012

Advertising
Share | | |
Site Map | Privacy & Security | Cookies | Terms and Conditions

PharmiWeb.com is Europe's leading industry-sponsored portal for the Pharmaceutical sector, providing the latest jobs, news, features and events listings.
The information provided on PharmiWeb.com is designed to support, not replace, the relationship that exists between a patient/site visitor and his/her physician.