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Job Details

Senior Research Associate I, DMPK

Company: SciPro
Location: San Francisco
Reference: HQOODMPK
Closing Date: 19 Jan 17
Type: Permanent
Salary (£): Negotiable
Benefits:

Job Summary:

We are seeking a highly motivated professional to join our rapidly expanding team and contribute to the discovery and development of novel anti-bacterial agents to address major unmet medical needs. The successful candidate will operate in a highly dynamic research environment, providing DMPK support and expertise. Attention to detail, focus on quality as well as a persistent drive for results are critical to this position. ...

Requirements:

We are seeking a highly motivated professional to join our rapidly expanding team and contribute to the discovery and development of novel anti-bacterial agents to address major unmet medical needs. The successful candidate will operate in a highly dynamic research environment, providing DMPK support and expertise. Attention to detail, focus on quality as well as a persistent drive for results are critical to this position.



Essential Functions

* Develop methods for and execute qualitative and quantitative LC/MS/MS-based bioanalysis to support in vivo PK studies of small molecule therapeutics.
* Develop, perform and interpret the results from in vitro ADME assays (e.g. protein binding, microsomal stability, P450 inhibition).
* Perform rigorous data quality controls to ensure quality and integrity.
* Organize, timely record and maintain study data.
* Participate to the coordination and management of outsourced in vitro and in vivo studies.
* Generate timely, high quality research reports/presentations and ensure proper archival.



Essential Experience

* A minimum of 4 years of experience with LC/MS in a bioanalytical laboratory in pharmaceutical R&D.
* Solid knowledge and demonstrated hands-on experience with qualitative/quantitative bioanalysis, sample preparation and the development and execution of in vitro assays.
* Familiarity with ABI Analyst, Excel, PowerPoint, WinNonlin and Prism.
* Proficiency in the interpretation of MS fragmentation.
* Standard laboratory instrument operation, maintenance and troubleshooting.
* Solid understanding of small molecule metabolism and of basic principles of in vivo pharmacokinetics.
* Experience with the operation of a high-resolution mass spectrometry is highly desirable.

Apply for this job: Senior Research Associate I, DMPK

Contact Information:

Address:  Head Office
4th Floor, 150 Leadenhall Street, London
EC3V 4TE
England
Tel:  +44(0)203 327 3072
Website:  Visit Our Web Site

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