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Features
Make your Last Impression Count!

21 Jun 04

Everyone knows that first impressions count. There have been countless articles on how to ‘Dress to impress’, and how to make sure the first five minutes of your interview are geared towards creating the perfect ‘First Impression’.
Lydia Holder

Sitaxentan as an effective treatment of pulmonary arterial hypertension

21 Jun 04

Pulmonary arterial hypertension (PAH) represents an unmet market. Initial breakthroughs in treatment focussed on the rare form of this condition, idiopathic pulmonary arterial hypertension. Recently however a key advance in the treatment of PAH was made with the launch of Actelion's twice-daily Tracleer (bosentan) as the first orally active treatment of both idiopathic and secondary PAH. Tracleer is the first generation of a class of drugs known as endothelin receptor antagonists and blocks two
LeadDiscovery

The development of a dual 5-LO inhibitor/H1 receptor antagonist for the treatment of asthma

20 Jun 04

Numerous inflammatory mediators have been implicated in the etiology of asthma. Blocking specific inflammatory mediators has frequently yielded unimpressive clinical results and instead the simultaneous targeting or more than one mediator may be of greater use. In the current edition of LeadDiscovery's TherapeuticAdvances work by researchers at UCB who have developed a dual 5-LO inhibitor/H1 receptor antagonist is highlighted
LeadDiscovery

PABORD - dedicated to Outsourcing in Research and Development

17 Jun 04

PABORD is the first exhibition and conference dedicated to Outsourcing in Research and Development for the Pharmaceutical and Biotechnology industries.
Simon Berger

I’m a Candidate Get me out of here!

17 Jun 04

As we all know, interviews come in three forms: The good, the bad, and sometimes… The downright ugly! This is an article about the latter; ugly interviews, from ‘unconventional’ interviewers, who wouldn’t know the words ‘Professional, Un-biased and Independent’ even if they came up and bit them!
Lydia Holder

Pharma NewsBytes: June 16th, 2004

16 Jun 04

Pharma NewsBytes selects out some of the most interesting press releases to have appeared on LeadDiscovery’s DailyUpdates tracking service over the past few weeks. This edition includes an update on selected releases from the American Society of Clinical Oncology and the American Diabetes Association as well as important news concerning the antipsychotic, Abilify (Aripiprazole) and novel HIV treatments
LeadDiscovery

DDP-IV inhibitors as candidates for metabolic disorders, cancer and as model molecules for optimizing intestinal absorption of new therapeutics

16 Jun 04

Researchers have developed a series of assays to identify improved DDP-IV inhibitors for the treatment of diabetes and possibly cancer. The technology described here can also be applied to improving the oral absorption of poorly absorbed drugs in general
LeadDiscovery

Biogenerics market presents new commercial opportunity

11 Jun 04

With several blockbuster biological products approaching patent expiry and the emergence of new approval pathways, the biogenerics segment represents an attractive opportunity for companies looking to escape intensifying competition in the commodity generics sector. However, with the biotech industry preparing significant opposition to any new regulatory initiatives, barriers to market entry could remain high.
Datamonitor

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