11 Feb 05
A significant rise in sales of InterMune's hepatitis drug Infergen, from $9.3 million in 2003 to $22.3 million in 2004, is the result of the company's focus on marketing Infergen to HCV non-responders. In targeting this vital patient sub-group, InterMune could gain a useful head start in an area of hepatitis treatment that is set to become fiercely competitive in the years ahead.
08 Feb 05
Atopic eczema (or atopic dermatitis) is the most common chronic skin disease in childhood, and it can have a significant impact on the lives of patients and their families. New and effective treatments have been introduced in recent years, and it has been postulated that good control of atopic eczema with these agents may also reduce the incidence and severity of asthma.
CSF Medical Communications
04 Feb 05
Five million adult asthmatics may have predominantly neutrophilic inflammation. Whilst this phenotype is usually associated with severe asthma, it may be more prevalent across the range of disease severities than originally thought. The emergence of this phenotype in asthma raises important implications for treatment practice.
03 Feb 05
Lupus is a chronic inflammatory disease that can affect various parts of the body, especially the skin, joints, blood, and kidneys. For most people, lupus is a mild disease affecting only a few organs. For others, it may cause serious and even life-threatening problems. In particular lupus nephritis claim a significant number of lives. More than 16,000 Americans develop lupus each year. It is estimated that 500,000 to 1.5 million Americans have been diagnosed with lupus. Current treatments focus
27 Jan 05
In contrast to coronary and cerebral artery disease, peripheral arterial disease (PAD) remains an under-appreciated condition that despite being serious and extremely prevalent is rarely diagnosed and even less frequently treated. This situation is now changing as physician awareness grows in parallel with increased use of existing therapeutics and the development of improved cardiovascular agents, gene therapies and devices
27 Jan 05
Get your hands on this unique free intelligence from eyeforpharma's recent Sales Force Effectiveness conferences in Europe and the USA.
24 Jan 05
For people with migraine, today’s world is a better world than the one their parents knew. The last 15 years have seen major advances, giving us not only a much clearer understanding of the disorder but also considerably more effective therapies. Treatments exist that – if made available and used in the right way – can substantially relieve the majority of people affected by migraine.
17 Jan 05
It is estimated that there are more than 38 million people in the seven major markets with diabetes and this figure is set to rise to 50 million in 2012. However, despite this vast potential patient population, low diagnosis rates, the chronic nature of the disease, the need for combination therapy, the lack of an oral antidiabetic agent offering effective long-term therapy and the association of injectable therapies with poor patient compliance mean that a broad spectrum of unmet needs exists.
17 Jan 05
Knowledge will be pooled and ideas investigated through focused discussion topics:
* What approach to take to target validation?
* Establishing the true impact of off-target effects
* Unravelling the different pathways
* What can delivery systems achieve?
* What are the pros and cons of different chemical modification?
* Addressing pharmacokinetics and modification issues for each disease
What do I need for clinical testing of an siRNA compound?
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