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Improved assay technology for the evaluation of airway therapeutic activity or toxicology

Posted on: 21 Jul 05

Summary

Assaying therapeutic agents requires the availability of apparatus to dose experimental animals as well as to measure biological effect. Available dosing systems for inhalation agents are suboptimal generally causing stress to the animal as well as exposing the operator to potentially harmful agents. Texas based researchers have developed an improved system for the delivery of agents to the airway

Assaying therapeutic agents requires the availability of apparatus to dose experimental animals as well as to measure biological effect.  Available dosing systems for inhalation agents are suboptimal generally causing stress to the animal as well as exposing the operator to potentially harmful agents.  Texas based researchers have developed apparatus that allows mice to be dosed with reproducible levels of test substance under medium-throughput and low stress conditions.  The system can be used to assay efficacy of airway therapeutics (including small molecules and gene therapies) and agents designed for airway delivery.  This dosing chamber system can also be used to safely evaluate the respiratory tract toxicology of test substances....[more]

Source LeadDiscovery

Featured on DailyUpdates-Immunology & Inflammatory Diseases

LeadDiscovery

Last updated on: 27/08/2010 11:40:18

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