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Research and Markets: What are European Physician and Payer Expectations for the Uptake of Emerging Oral Immunomodulators in Rheumatoid Arthritis?

Research and Markets
Posted on: 03 Oct 12

Research and Markets ( has announced the addition of Decision Resources, Inc's new report "What are European Physician and Payer Expectations for the Uptake of Emerging Oral Immunomodulators in Rheumatoid Arthritis?" to their offering.

The moderate-to-severe RA population is a lucrative indication for immune-targeted agents owing to its high prevalence and size of the patient population refractory to cheap and generic conventional therapies.

However, the barriers to entry are high given the number of effective biologic therapies already marketed; these include five tumor necrosis factor-alpha (TNF-a) inhibitors, Bristol-Myers Squibb/Ono Pharmaceutical's selective costimulation modulator Orencia, Roche's MabThera (Roche/Biogen Idec Chugai/Zenyaku Kogyo's B-cell inhibitor Rituxan), and the more recently-launched interleukin-6 (IL-6) inhibitor Actemra/RoActemra from Roche/Chugai.

However, two oral agents Pfizer/Takeda's tofacitinib (CP-690550) and AstraZeneca's fostamatinib disodium (R-788)are set to launch in Europe over the next four years and aim to compete with the TNF-a inhibitors. The introduction of novel formulations for three already-marketed biologics (including subcutaneous formulations of Orencia and RoActemra) has the potential to further fragment the moderate-to-severe RA market.

Key Topics Covered:

Executive Summary Slides

Commercial Context Slides

Methodology Slides

Methodology Slides

Overview and Analysis of Reimbursement in the EU5 Slides

Analysis of Survey Results Slides

About the Author Slide

For Further Information Slide

For more information visit

Source: Decision Resources, Inc

Business Wire

Last updated on: 03/10/2012

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