Pharmiweb ChannelsAll | PharmaCo | Clinical Research | R&D/BioTech | Sales/Mktg | Healthcare | Recruitment | Pharmacy | Medical Comms RSS Feed RSS Feeds


It's not just drug discovery that's an expensive business

23 Aug 04

Pharmaceutical practices from manufacturing to marketing are coming under increasing scrutiny from watchdogs, regulators and shareholders. As huge fines and record settlements erode profits, Datamonitor's Andrew Jones argues that pharma companies must focus on tightening compliance...


23 Aug 04

Eventually, methods developed by research laboratories need to be transferable to face the rigours of external validation or the production line. Many researchers, however, are unaware that this procedure must be adequately documented, a crucial issue when it comes to regulation and outsourcing.
Rachel Holdsworth/Geoff Pulham

Singapore strives for success

22 Aug 04

As the pharmaceutical industry expands its global outlook, many companies have taken a greater interest in the region of South-East Asia. The emergence of this area as a centre for R&D activities is typified by Singapore, which has made a strong commitment to raising its profile and attracting major companies.
Dr Faiz Kermani

Researchers report on the role of estrogen in airway function: Can menopause accelerate the progression of COPD?

19 Aug 04

DailyUpdates 18th August, 2004: Recent data suggest that women may be more susceptible to the chronic airway disorders emphysema and bronchitis, together known as chronic obstructive pulmonary disease (COPD). The reasons for this are unclear however data published this month demonstrate a key role of the estrogen receptor in maintaining alveolar surface area and airway elasticity. This suggests that menopause may contribute to the acceleration of COPD and prompts investigation into the develop

Can you Sell Yourself?

18 Aug 04

After my many years of conducting interviews and recruiting for both junior and senior employees, I have come to the conclusion that if there is one single thing that a person can do to secure a second interview or a desired position it is believe in themselves.
Susan Mason

Proteolytic beta amyloid light chain antibody fragments offer promise as future treatments of Alzheimer’s disease.

17 Aug 04

DailyUpdates 18th August, 2004: Researchers from at Arizona State University have demonstrated that beta amyloid light chain proteolytic antibody fragments can cleave beta-amyloid, altering the aggregation and neutralizing the cytotoxic effects of this peptide.

Antibody-drug conjugates offer hope for the treatment of hormone resistant prostate cancer

17 Aug 04

DailyUpdates 17th August, 2004: Researchers from Protein Design Laboratories report that an antibody-drug conjugate that links the chemotherapeutic agent Auristatin to a prostate cancer specific antibody, anti-TMEFF2 mAb, via a cathepsin B-sensitive linker prevents tumor growth in a murine model of prostate cancer.

New rhinitis therapy should help patients to breathe easy

13 Aug 04

Rigel's new intranasal inhibitor R112 could offer a useful alternative therapy for patients suffering from allergic rhinitis, as Datamonitor's Shaun Falkingbridge explains. Bolstered by supportive recent trial results, Rigel can now go on to seek partner firms to realize full commercialization of the drug...

US online pharmacies can attract consumers from cross-border discounters

12 Aug 04

The trade in discounted prescription drugs between Canada and the US has elicited considerable controversy on both sides of the border. Yet recent figures show that sales of drugs via Canadian pharmacies have not been as great as some had predicted. However, as Datamonitor's David Deon explains, pharmaceutical companies could go further by driving the expansion of online prescribing in the US...

Lipoxin A4 (LXA4) mimics shown reduce inflammation by inhibiting the p38-MAPK pathway-further proof of concept for LXA4 analogues in preclinical development

11 Aug 04

The p38-MAPK pathway has long been targeted by the pharmaceutical industry in an attempt to identify new anti-inflammatory agents. The development of p38-MAPK inhibitors has however been impeded by adverse effects. Boston University researchers have now demonstrated that the lipoxin A4 (LXA4) mimic, ATLa inhibits the p38-MAPK cascade explaining in part its anti-inflammatory efficacy and offering a new approach to this promising pharmaceutical target. Although ATLa has a poor pharmacokinetic p

Site Map | Privacy & Security | Cookies | Terms and Conditions is Europe's leading industry-sponsored portal for the Pharmaceutical sector, providing the latest jobs, news, features and events listings.
The information provided on is designed to support, not replace, the relationship that exists between a patient/site visitor and his/her physician.