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Two Day Seminar: Drug Dissolution Testing and Establishing Plasma Drug Levels in Humans (Washington, DC, United States - February 8-9, 2018) - Research and Markets

Research and Markets
Posted on: 03 Jan 18

The "Drug Dissolution Testing and Establishing Plasma Drug Levels in Humans" conference has been added to Research and Markets' offering.

This seminar will provide relevant pharmacokinetics and physiological background so that making this choice becomes easier and instinctive. No prior knowledge of pharmacokinetic and/or physiology is required; however, these will be explained in very simple terms to help attendees in selecting or developing a dissolution method.

This seminar will describe in detail the theoretical aspect of the drug dissolution testing including method development. Pros and cons of different approaches will be explained in detail.

Furthermore, drug dissolution testing is extensively conducted to provide an estimate/prediction of expected drug levels in humans. Commonly, concepts of convolution/deconvolution and in vitro-in vivo correlation (IVIVC) are described in this respect, unfortunately with limited success. Difficulties and limitations of the currently suggested approaches will be highlighted.

This seminar will provide details of the underlying scientific principles involved in convolution, deconvolution and IVIVC techniques with simple practical examples. In this regard, a unique and simple approach based on convolution technique using spreadsheet software will be described.

Pharmaceutical product developments and assessments require extensive use of in vitro drug dissolution testing and convolution/deconvolution techniques for predicting plasma drug levels. Often such testing are presented in isolation (independent to their physiological link or relevance), however, this seminar will train attendees for developing these techniques using the principles of pharmacokinetics and physiology. The seminar will provide unique opportunity to learn scientifically valid drug dissolution testing and establishing plasma drug levels.

Areas Covered in the Session

  • Physiological and Pharmacokinetic Principles
  • Drug Dissolution Testing
  • Linking Dissolution Results to Plasma Drug Levels

For more information about this conference visit

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Last updated on: 03/01/2018

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