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Press Release

Dexferrum (iron dextran; Luitpold Pharmaceuticals) Drug Analysis 2018 -

Research and Markets
Posted on: 20 Feb 18

The "Drug Analysis: Dexferrum" drug pipelines has been added to's offering.

Dexferrum (iron dextran; Luitpold Pharmaceuticals) is an intravenous (IV) iron maintenance treatment used to help elevate hemoglobin levels in patients with anemia in chronic kidney disease (CKD).

The iron is transported via transferrin to erythroid precursor cells. Erythroid precursor cells incorporate the iron into hemoglobin as the cell matures into a red blood cell. Dexferrum, and other iron therapies, are often used in combination with erythropoiesis-stimulating agent (ESA) therapies to increase the number of patients able to achieve target hemoglobin levels compared to patients on ESA therapies alone (Singh, 2008).

Dexferrum has a significantly less attractive clinical and commercial profile compared to more recent IV iron therapies, Injectafer (ferric carboxymaltose; Vifor/Luitpold Pharmaceuticals/Zeria), Venofer (poly-nuclear iron (III)-hydroxide in sucrose; Vifor/Luitpold Pharmaceuticals), and Feraheme (ferumoxytol; AMAG Pharmaceuticals), due to increased risk of iron toxicity and a highly inconvenient dosing strategy.

Key Topics Covered:

Product Profiles

Dexferrum: Anemia in chronic kidney disease

List of Figures

Figure 1: Dexferrum sales for anemia in chronic kidney disease across the five major EU markets, by country, 2015-24

List of Tables

Table 1: Dexferrum sales for anemia in chronic kidney disease across the five major EU markets, by country ($m), 2015-24

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Last updated on: 20/02/2018

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