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Press Release

Global Hormone Replacement Therapy (HRT) Business Report 2018 -

Research and Markets
Posted on: 16 Nov 18

The "Hormone Replacement Therapy (HRT) - Global Strategic Business Report" report has been added to's offering.

The report provides separate comprehensive analytics for the US, Canada, Europe, Asia-Pacific, Latin America, and Rest of World. Annual estimates and forecasts are provided for the period 2016 through 2024. Also, a five-year historic analysis is provided for these markets. This report analyzes the worldwide markets for Hormone Replacement Therapy (HRT) in US$ Thousand.

The report profiles 31 companies including many key and niche players such as:

  • Abbott Laboratories
  • Allergan
  • Bayer
  • Novartis
  • Noven Pharmaceuticals
  • Novo Nordisk
  • Orion Pharma
  • Pfizer
  • TherapeuticsMD

Key Topics Covered:



An Introduction to Menopause and Hormone Replacement Therapy

The HRT Controversy - An Insight

Newer Studies Challenge WHI Findings and Re-establish Safety of HRT

Revised Recommendations of the NAMS and Endocrine Society

IMS Consensus Guidelines Paving Way for More Clarity of HRT

The HRT Controversy Evolution in the New Millennium

The Regional Divide

Increasing Number of Menopausal Women - A Major Market Driver

New Bioidentical Drugs Serve Unmet Market Needs

Generic Incursion in Hormone Replacement Therapy - List of Drugs With and Without Approved Generic Versions

Intense Competition Marks the Global HRT Market

The Premarin Saga

Health Risks Tarnish Premarin's Image

Better Safety Profile for Duavee - A Shot in the Arm for Pfizer

Estrace Cream Drives Revenue Gains in Allergan's HRT Portfolio


Unmet Needs in Combination Therapies for HRT drive Research for New Medicines

Topical Estrogens - More Safe and Effective

Transdermal HRT Products Present Exciting Opportunities

Phytoestrogens - The New Panacea for Menopausal Symptoms?

Diet Link to Menopause Symptoms Raises Interest

Impact of Soy and Other Phytoestrogens - A Reality Check

Select Botanical Treatments Studied for Menopause Symptoms Treatment and Identified Risks and Limitations

EstroG - A Successful Herbal Health Supplement in Alleviating Menopausal Symptoms

The Growing Buzz around Bioidentical Drugs

Bio-identical Hormones - A Natural and Safe Substitute to Synthetic HRT?

List of Bio-identical Products Used in Conventional HRT

Pellet Therapy - A New Innovation Downsizes Conventional Issues with Bioidentical HRT

Direct-to-Consumer Advertising for HRT - A Mixed Bag

Estriol: The Next Generation Estrogen Therapy?

What Makes Estriol Work?

Topical Estriol - More Promising in Safety

Estriol - Used More Commonly Outside the US

Entry of Generics Threatens Market Growth Prospects

Are Non-Hormonal Therapies A Threat to HRT?

Earlier Failures Induce Lethargy in Non-Hormonal Therapies


Study Shows Hormone Therapy Potentially Eases Depression

Higher Risk of Breast Cancer with Combined-HRT than with Oestrogen-Only HRT

New Meta-Analysis Positively Links Ovarian Cancer to Use of HRT, Albeit Modest

HRT for Reducing Belly Fat

HRT for Women who are Cancer Survivors


What are Hormones?

What is Menopause?

Menopause Symptoms and Complaints

Introduction to Hormone Replacement Therapy

HRT Products



Milestones and Downfalls in the Hormone Replacement Therapy (HRT) Market

Contraindications of HRT

Historical Progression

Advantages and Disadvantages of Using HRT

Benefits of Hormone Therapy

Relief from Vasomotor Symptoms

Vaginal Symptoms

Improvement in Sexual Functioning

Urinary Health

Management of Variations in Body Weight/Mass

Ensuring Quality of Life


Diabetes Mellitus (DM)

Impact on Overall Mortality

Treatment of Premature Menopause

Risks Involved in Hormone Therapy

Hormone Therapies in HRT and their Effect

Potential Benefits and Risks of HRT in Menopausal Symptoms

Common and Less Common Side Effects of Using Estrogen-alone, Progesterone-alone or Combination Therapies

Potential Issues

Cardiovascular Problems

Coronary Heart Disease (CHD)


Venous Thromboembolism (VTE)

Endometrial Cancer

Breast Cancer

Estrogen-Progestogen Therapy

Estrogen Therapy

Lung Cancer

Depression and Mood Swings

Ovarian Cancer

Routes of Administration

Systemic Treatment


Advantages and Disadvantages of Oral HRT

Vaginal Estrogen Ring

Transdermal Estrogen Skin Patches

Localized Treatment

Vaginal Estrogen Tablets

Estrogen Creams

Intrauterine Progestin System (IUS)

Lower Dose Vaginal Estrogen Ring

Vaginal Progesterone Gel


Advantages and Disadvantages of HRT Implants

Bioidentical Hormone Replacement Therapy (BHRT)

Historical Background

More Claims than Evidence

Other Alternatives

Prescription Medication





Black Cohosh

Phytoestrogens (Isoflavones)

Other Botanical Products

Non-botanical Supplements

Mind/Body therapies

Exercise and Diet


6.1 Focus on Select Global Players

6.2 Product Introductions/Approvals

TherapeuticsMD Receives Approval from FDA for TX-001HR: BIJUVA

TherapeuticsMD Announces the availability of Imvexxy 4 mcg for Commercial Use

TherapeuticsMD Obtains FDA approval for TX-004HR: IMVEXXY

Teva Launches Authorized Generic of Estrace Cream in the United States

Teva Introduces Generic Axiron in the United States

Teva Launches Generic Vagifem in the United States

MSD Introduces Duavive in UK for Treating Oestrogen-deficiency Symptoms in Post-menopausal Women

6.3 Recent Industry Activity

Juniper Pharmaceuticals Signs Licensing Agreement with Dar Bioscience for Intravaginal Ring (IVR) Platform

Teva Announces the Divesture of Global Women's Health to CVC Capital Partners



8.1 The United States

Newer Trials Negate WHI Findings and Boost HRT Market

The Menopause Opportunity

Ethnic Differences Exist in Menopausal Symptoms

Increasing Preference for Topical Vaginal Products

Rising Interest in Low-Dose Hormone Therapies to Lead Market Growth

FDA Appealed to Make Changes to Boxed Warnings on Low-Dose Vaginal Estrogen to Drive Adoption

Low-Dose Hormone Replacement Therapy Formulations of Estrogens and Estrogen-Progestin Combinations Available in the United States

Bioidenticals Gaining Attention in the US Market

Custom Compounded Bioidenticals

Growing Pharmacy Compounding of HRT Raises Concerns; DQSA Puts Shackles

8.2 Canada

Canada - The Birth Place of Estrogens

Current Market Scenario

8.3 Europe

Current & Future Analysis

Growing Demand for Topical and Transdermal HRT

European Medicines Agency Imposes New Restrictions on Linoladiol HN and Linoladiol N Estradiol Creams

8.3.1 France

A Peek into the HRT Prescription Practices in France

8.3.2 Germany

8.3.3 Italy

8.3.4 The United Kingdom

Post-Menopausal Symptoms in British Women

British Menopause Society and Women's Health Concern Revises Recommendations on HRT

List of the Hormone Replacement Therapy Products Available in the UK

List of HRT Products Available in the UK by Format

New Guidelines from NHS May Improve Uptake of HRT

8.3.5 Spain

HRT Prescription Status in Spain

8.4 Asia-Pacific

8.5 Latin America

8.6 Rest of World


Total Companies Profiled: 31 (including Divisions/Subsidiaries - 39)

  • The United States (17)
  • Canada (3)
  • Japan (2)
  • Europe (12)
    • Germany (2)
    • The United Kingdom (4)
    • Rest of Europe (6)
  • Asia-Pacific (Excluding Japan) (4)
  • Middle East (1)

For more information about this report visit

View source version on

Business Wire

Last updated on: 16/11/2018

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