Can-Fite CEO to present as Expert Speaker on Namodenoson at NASH Summit Europe 2018
Can-Fite BioPharma Ltd. (NYSE American: CANF) (TASE:CFBI), a biotechnology company advancing a pipeline of proprietary small molecule drugs that address liver and inflammatory diseases, today announced that its CEO, Dr. Pnina Fishman, will join other global thought-leaders in the field of non-alcoholic steatohepatitis (NASH) to speak at NASH Summit Europe in Frankfurt, Germany on October 22, 2018. She will deliver her presentation titled, “The Polypharmacological Anti-NASH Effects of Namodenoson are Mediated via De-Regulation of the Wnt/βcatenin Pathway” at 11:00 am on Thursday, October 24, 2018.
“I am pleased to be invited to speak at NASH Summit Europe and to share Can-Fite’s Namodenoson molecular mechanism of action in inhibiting the manifestations of NAFLD/NASH. Namodenoson represents a novel therapy approach for the treatment of NASH and its precursor, non-alcoholic fatty liver disease (NAFLD). As NAFLD/NASH impact a growing number of people, the industry is coming together in summits like this to accelerate the path to developing and bringing to market effective diagnostics and treatments for patients living with this disease,” Dr. Fishman stated.
Can Fite will present pre-clinical data from three experimental animal models showing that the anti-inflammatory, anti-steatotic and anti-fibrogenic effect of Namodenoson are mediated via the Wnt/β-catenin pathway, highly active in the liver of NAFLD/NASH animals or individuals.
Can-Fite’s is currently enrolling patients for a Phase II NAFLD/NASH study in three Israeli sites, including Hadassah Medical Center, Jerusalem, and the Rabin Medical Center, Petach Tikva. The Company anticipates the completion of patient enrollment toward the end of 2018 and data release in the first half of 2019.
About Can-Fite BioPharma Ltd.
Can-Fite BioPharma Ltd. (NYSE American: CANF) (TASE: CFBI) is an advanced clinical stage drug development Company with a platform technology that is designed to address multibillion-dollar markets in the treatment of cancer, inflammatory disease and sexual dysfunction. The Company’s lead drug candidate, Piclidenoson, is currently in a Phase III trial for rheumatoid arthritis and psoriasis. Can-Fite’s liver cancer drug, Namodenoson, is in Phase II trials for hepatocellular carcinoma (HCC), the most common form of liver cancer, and for the treatment of non-alcoholic steatohepatitis (NASH). Namodenoson has been granted Orphan Drug Designation in the U.S. and Europe and Fast Track Designation as a second line treatment for HCC by the U.S. Food and Drug Administration. Namodenoson has also shown proof of concept to potentially treat other cancers including colon, prostate, and melanoma. CF602, the Company’s third drug candidate, has shown efficacy in the treatment of erectile dysfunction in preclinical studies and the Company is investigating additional compounds, targeting A3AR, for the treatment of sexual dysfunction. These drugs have an excellent safety profile with experience in over 1,000 patients in clinical studies to date. For more information please visit: www.can-fite.com.
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