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16-Jan-2019

Post-Hoc Analyses from Pivotal Phase 3 REFLECT Trial of LENVIMA® (lenvatinib) in Unresectable Hepatocellular Carcinoma to be Presented at 2019 Gastrointestinal Cancers Symposium

WOODCLIFF LAKE, N.J., Jan. 14, 2019 /PRNewswire/ -- Eisai Inc. announced today the presentation of four abstracts at the 2019 Gastrointestinal Cancers Symposium (#GI19), taking place in San Francisco from January 17-19, 2019. The presentations feature the latest data from post-hoc analyses of the pivotal phase 3 REFLECT trial (Study 304) of lenvatinib (marketed as LENVIMA®), an orally available kinase inhibitor discovered by Eisai, for the first-line treatment for unresectable hepatocellular carcinoma (HCC).

Presentations of interest include:

An oral presentation on a landmark analysis of the relationship between overall survival (OS) and objective response (OR) in patients from REFLECT.

A poster presentation on a post-hoc analysis of responders from REFLECT who received first-line lenvatinib and subsequent anticancer medication during survival follow-up.

"Our data at this year's GI Cancers Symposium provides important clinical insights—with the potential to better assess and further define the treatment paradigm for patients with unresectable HCC," said Alton Kremer, MD, PhD, Chief Clinical Officer and Chief Medical Officer, Oncology Business Group at Eisai. "At Eisai, the patients we serve are what fuel our drive to continue evaluating and exploring effective ways to approach difficult-to-treat cancers, and these data are one more example of our efforts to deliver on our commitment to patients."

Additionally, a needs assessment developed and conducted by the Association of Community Cancer Centers (ACCC) that identifies factors associated with delivery and coordination of care for patients with HCC in community settings will also be presented. This research was conducted via an unrestricted grant from Eisai.

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Last Updated: 16-Jan-2019