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Detecting Tumor Marking Tags Deep Within Body With The Help Of Hyperspectral Imaging

Light can only penetrate so far through tissues without losing most of the data it carries. This makes it very difficult to visualize tumors deep within the body. Alternatives like fluorescent markers and radioactive markers are also not fool proof. While radioactive markers can be dangerous, in case of fluorescent markers, those that can in fact highlight the existence of tumor cells have to be visible in order for them to help with diagnosis. Spotting large lesions can be attempted with the help of alternatives like MRIs and CT scanners; however when it comes detecting early tumor formation, not much can be done and thus they go unnoticed.

Imaging and spotting things inside the body not much more than about three centimeters in depth can successfully be done with the help of light, particularly at longer wavelengths. Thus it has been concluded that principally this is the limit that can be touched. However, a technology that facilitates in tracking track tiny fluorescent probes down to eight centimeters of tissue depth has been developed by the researchers and MIT University.

In case of fluorescent markers, normally they glow at a single frequency. Once they are deep enough inside the tissue, their glow fuses with one another. This make the details get lost in the course. In order to be able to detect the accurate location of individual probes, a combination of different frequencies, along with a technique called hyperspectral imaging has been used by the researchers at MIT.

The technology ldquo;Detection of Optically Luminescent Probes using Hyperspectral and diffuse Imaging in Near-infrared,rdquo; has been acronymed as DOLPHIN. It might soon be available as a new modality for spotting deep seated cancers, as it works with approved fluorescent markers.

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Last Updated: 20-Mar-2019