PharmiWeb.com - Global Pharma News & Resources
18-Jul-2019

Downstream Processing Market Will Grow 40.1% to a Record $ 14.0 Billion by 2026

The Global Downstream Processing Market Size projected to register USD 40.1 billion by 2026, registering at a CAGR growth of 14.0% over the forecast period 2018 to 2026. Surge in acceptance and adoption of biotech processes in the agricultural, pharmaceutical, and bio-services industries is anticipated to boot the market over the forthcoming years.

The global downstream processing market is segmented into four major segment named product, technique, application, and region. On the basis of product the downstream processing market is segmented into chromatography systems, filters, evaporators, centrifuges, dryers and others. On the basis of the technique the global downstream processing market is segmented into cell disruption, solid-liquid separation (filtration, centrifugation) concentration (evaporation, membrane filtration), and purification by chromatography and formulation. These solid-liquid separation are further bifurcated into filtration, and centrifugation, and the concentration is also further segmented evaporation, and membrane filtration. On the basis of application, the downstream processing market is segmented into antibiotic production, hormone production, antibodies production, enzyme production, and vaccine production. On the basis of region the global downstream processing market is segmented into North America, Europe, Asia Pacific, Latin America and Middle East amp; Africa.

Main market participants delivers safe and integrated chromatography solutions that work efficiently throughout all steps of a bioprocess. In current years, key vendors have established technologically competent systems that address emerging needs of the industry to accomplish state-of-the-art chromatography steps throughout manufacturing of bio-therapeutics. Such as, single-use chromatography is single of the most important inventions of the biopharmaceutical business.

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Single-use chromatography eradicates the need for large-scale chromatography columns, resin storage, column packing, and storage of packed columns. The technology has also led to reduction in water and chemicals for cushion to as much as 80.0%. This safeguards augmented productivity and competence of bioprocess in less time and with abridged labor.

Filter manufacturers have been emerging progressive filters with high performance due to growing need for viral clearance. Viruses can brutally damage an entire process stream. There are numerous micro and ultra-filters commercially accessible in the market. A few instances of the same comprise of Viresolve filters from Merck Millipore, Planova virus removal filters from Asahi-Kasei, and Virosart brand from Sartorius Stedim Biotech.

Also, to virus clearance, sterile filtration is also deployment for removal of certain antibiotic resistant bacterial species for instance Mycoplasma. Filters deployment for this purpose comprise of Millipore Express from Merck, Nalgene PES filters and Fluorodyne from Pall Corporation (Danaher).

Antibodies are one of the most major modalities obtainable by the biopharmaceutical sector today. This accomplishment is due to establishment of robust manufacturing platforms that generate high titers for monoclonal antibodies in mammalian cell cultures.

Also, development of certain new methods in bio processing of antibodies have additional increased the market. These new methods comprise of constant alternative expression systems, bio manufacturing, and nonâ€chromatographic separation formats.

Furthermore, as antibiotic resistance is on increase, there is asurge in need for growth of antibodies that act against resistant strains. This, in turn, is growing the need for downstream processing for antibody production at industrial scale.

North America captures the largest the global downstream processing market in 2018. The development of the region can be attributed to augmented focus of government bodies on the growth of the biotechnology industry, increasing healthcare expenditure, and occurrence of adequate infrastructure for development and growth of bio processing industries. Due to recent progressions, there is a considerable increase in sales of biotechnology products in the region. Consequently, continual innovations in the biotechnology sector are possible to deliver plenty development opportunities to the regional market during the forecast timeframe.

The key players operating in the global downstream processing market are General Electric Company (GE Healthcare), Thermo Fisher Scientific Inc., Merck KGaA (Merck Millipore), Sartorius Stedim Biotech S.A., and Danaher Corporation. Some other players catering to the market are Dover Corporation (CPC (Colder Products Co.)), Repligen, Boehringer Ingelheim International GmbH, 3M Company, Eppendorf AG, Corning Corporation, Ashai Kasei, Lonza Group Ltd, and Ferner PLC. These market player are investing massive wealth to transform the product line as the rivalry in the market is increasing with rapid pace. Likewise, with varying technology the need for better technology infrastructures are rising, so cater the need of the customers, market participants are continuously inventing new products.

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TABLE OF CONTENT

CHAPTER 1. INDUSTRY OVERVIEW

1.1. Definition and Scope
1.1.1. Definition of Downstream Processing Market
1.1.2. Market Segmentation
1.1.3. List of Abbreviations
1.2. Summary
1.2.1. Market Snapshot
1.2.2. Downstream Processing Market By Product
1.2.2.1. Global Downstream Processing Market Revenue and Growth Rate Comparison By Product (2015-2026)
1.2.2.2. Global Downstream Processing Market Revenue Share By Product in 2017
1.2.2.3. Chromatography Systems
1.2.2.4. Filters
1.2.2.5. Evaporators
1.2.2.6. Centrifuges
1.2.2.7. Dryers
1.2.2.8. Others
1.2.3. Downstream Processing Market By Application
1.2.3.1. Global Downstream Processing Market Revenue and Growth Rate Comparison By Application (2015-2026)
1.2.3.2. Cell Disruption
1.2.3.3. Solid-liquid separation
1.2.3.4. Concentration
1.2.3.5. Purification by Chromatography
1.2.3.6. Formulation
1.2.3.7. Others
1.2.4. Downstream Processing Market By Technique
1.2.4.1. Global Downstream Processing Market Revenue and Growth Rate Comparison By Technique (2015-2026)
1.2.4.2. Antibiotic Production
1.2.4.3. Hormone Production
1.2.4.4. Antibodies Production
1.2.4.5. Enzyme Production
1.2.4.6. Vaccine Production
1.2.4.7. Others
1.2.5. Downstream Processing Market by Geography
1.2.5.1. Global Downstream Processing Market Revenue and Growth Rate Comparison by Geography (2015-2026)
1.2.5.2. North America Downstream Processing Market Revenue and Growth Rate (2015-2026)
1.2.5.3. Europe Downstream Processing Market Revenue and Growth Rate (2015-2026)
1.2.5.4. Asia-Pacific Downstream Processing Market Revenue and Growth Rate (2015-2026)
1.2.5.5. Latin America Downstream Processing Market Revenue and Growth Rate (2015-2026)
1.2.5.6. Middle East and Africa (MEA) Downstream Processing Market Revenue and Growth Rate (2015-2026)

CHAPTER 2.MARKETDYNAMICS AND COMPETITION ANALYSIS

2.1. Market Drivers
2.2. Restraints and Challenges
2.3. Growth Opportunities
2.4. Porterrsquo;s Five Forces Analysis
2.4.1. Bargaining Power of Suppliers
2.4.2. Bargaining Power of Buyers
2.4.3. Threat of Substitute
2.4.4. Threat of New Entrants
2.4.5. Degree of Competition
2.5. Value Chain Analysis
2.6. Cost Structure Analysis
2.6.1. Raw Material and Suppliers
2.6.2. Manufacturing Process Analysis
2.7. Regulatory Compliance
2.8. Competitive Landscape, 2017
2.8.1. Player Positioning Analysis
2.8.2. Key Strategies Adopted By Leading Players

CHAPTER 3. MANUFACTURING PLANTS ANALYSIS

3.1. Capacity and Hormone Production Production Date of Global Downstream Processing Market Major Manufacturers in 2017
3.2. Manufacturing Plants Distribution of Global Downstream Processing Market Major Manufacturers in 2017
3.3. Ramp;D Status and Technology Source of Global Downstream Processing Market Major Manufacturers in 2017
3.4. Raw Materials Sources Analysis of Global Downstream Processing Market Major Manufacturers in 2017

CHAPTER 4. DOWNSTREAM PROCESSING MARKET BY PRODUCT

4.1. Global Downstream Processing Market Revenue By Product
4.2. Chromatography Systems
4.2.1. Market Revenue and Growth Rate, 2015 - 2026 ($Million)
4.2.2. Market Revenue and Forecast, By Region, 2015 - 2026 ($Million)
4.3. Filters
4.3.1. Market Revenue and Growth Rate, 2015 - 2026 ($Million)
4.3.2. Market Revenue and Forecast, By Region, 2015 - 2026 ($Million)
4.4. Evaporators
4.4.1. Market Revenue and Growth Rate, 2015 - 2026 ($Million)
4.4.2. Market Revenue and Forecast, By Region, 2015 - 2026 ($Million)
4.5. Centrifuges
4.5.1. Market Revenue and Growth Rate, 2015 - 2026 ($Million)
4.5.2. Market Revenue and Forecast, By Region, 2015 - 2026 ($Million)
4.6. Dryers
4.6.1. Market Revenue and Growth Rate, 2015 - 2026 ($Million)
4.6.2. Market Revenue and Forecast, By Region, 2015 - 2026 ($Million)
4.7. Other
4.7.1. Market Revenue and Growth Rate, 2015 - 2026 ($Million)
4.7.2. Market Revenue and Forecast, By Region, 2015 - 2026 ($Million)

CHAPTER 5. DOWNSTREAM PROCESSING MARKET BY APPLICATION

5.1. Global Downstream Processing Market Revenue By Application
5.2. Cell Disruption
5.2.1. Market Revenue and Growth Rate, 2015 - 2026 ($Million)
5.2.2. Market Revenue and Forecast, By Region, 2015 - 2026 ($Million)
5.3. Solid-liquid separation
5.3.1. Market Revenue and Growth Rate, 2015 - 2026 ($Million)
5.3.2. Market Revenue and Forecast, By Region, 2015 - 2026 ($Million)
5.4. Concentration
5.4.1. Market Revenue and Growth Rate, 2015 - 2026 ($Million)
5.4.2. Market Revenue and Forecast, By Region, 2015 - 2026 ($Million)
5.5. Purification by Chromatography
5.5.1. Market Revenue and Growth Rate, 2015 - 2026 ($Million)
5.5.2. Market Revenue and Forecast, By Region, 2015 - 2026 ($Million)
5.6. Formulation
5.6.1. Market Revenue and Growth Rate, 2015 - 2026 ($Million)
5.6.2. Market Revenue and Forecast, By Region, 2015 - 2026 ($Million)
5.7. Others
5.7.1. Market Revenue and Growth Rate, 2015 - 2026 ($Million)
5.7.2. Market Revenue and Forecast, By Region, 2015 - 2026 ($Million)

CHAPTER 6. DOWNSTREAM PROCESSING MARKET BY TECHNIQUE

6.1. Global Downstream Processing Market Revenue By Technique
6.2. Antibiotic Production
6.2.1. Market Revenue and Growth Rate, 2015 - 2026 ($Million)
6.2.2. Market Revenue and Forecast, By Region, 2015 - 2026 ($Million)
6.3. Hormone Production
6.3.1. Market Revenue and Growth Rate, 2015 - 2026 ($Million)
6.3.2. Market Revenue and Forecast, By Region, 2015 - 2026 ($Million)
6.4. Antibodies Production
6.4.1. Market Revenue and Growth Rate, 2015 - 2026 ($Million)
6.4.2. Market Revenue and Forecast, By Region, 2015 - 2026 ($Million)
6.5. Enzyme Production
6.5.1. Market Revenue and Growth Rate, 2015 - 2026 ($Million)
6.5.2. Market Revenue and Forecast, By Region, 2015 - 2026 ($Million)
6.6. Vaccine Production
6.6.1. Market Revenue and Growth Rate, 2015 - 2026 ($Million)
6.6.2. Market Revenue and Forecast, By Region, 2015 - 2026 ($Million)
6.7. Others
6.7.1. Market Revenue and Growth Rate, 2015 - 2026 ($Million)
6.7.2. Market Revenue and Forecast, By Region, 2015 - 2026 ($Million)

CHAPTER 7. NORTH AMERICA DOWNSTREAM PROCESSING MARKET BY COUNTRY

7.1. North America Downstream Processing Market Revenue and Growth Rate, 2015 - 2026 ($Million)
7.2. North America Downstream Processing Market Revenue Share Comparison, 2015 amp; 2026 (%)
7.3. U.S.
7.3.1. U.S. Downstream Processing Market Revenue and Forecast By Product, 2015 - 2026 ($Million)
7.3.2. Market Revenue and Forecast By Application, 2015 - 2026 ($Million)
7.3.3. Market Revenue and Forecast By Technique, 2015 - 2026 ($Million)
7.4. Canada
7.4.1. Market Revenue and Forecast By Product, 2015 - 2026 ($Million)
7.4.2. Market Revenue and Forecast By Application, 2015 - 2026 ($Million)
7.4.3. Market Revenue and Forecast By Technique, 2015 - 2026 ($Million)
7.5. Mexico
7.5.1. Market Revenue and Forecast By Product, 2015 - 2026 ($Million)
7.5.2. Market Revenue and Forecast By Application, 2015 - 2026 ($Million)
7.5.3. Market Revenue and Forecast By Technique, 2015 - 2026 ($Million)

CHAPTER 8. EUROPE DOWNSTREAM PROCESSING MARKET BY COUNTRY

8.1. Europe Downstream Processing Market Revenue and Growth Rate, 2015 - 2026 ($Million)
8.2. Europe Downstream Processing Market Revenue Share Comparison, 2015 amp; 2026 (%)
8.3. UK
8.3.1. Market Revenue and Forecast By Product, 2015 - 2026 ($Million)
8.3.2. Market Revenue and Forecast By Application, 2015 - 2026 ($Million)
8.3.3. Market Revenue and Forecast By Technique, 2015 - 2026 ($Million)
8.4. Germany
8.4.1. Market Revenue and Forecast By Product, 2015 - 2026 ($Million)
8.4.2. Market Revenue and Forecast By Application, 2015 - 2026 ($Million)
8.4.3. Market Revenue and Forecast By Technique, 2015 - 2026 ($Million)
8.5. France
8.5.1. Market Revenue and Forecast By Product, 2015 - 2026 ($Million)
8.5.2. Market Revenue and Forecast By Application, 2015 - 2026 ($Million)
8.5.3. Market Revenue and Forecast By Technique, 2015 - 2026 ($Million)
8.6. Spain
8.6.1. Market Revenue and Forecast By Product, 2015 - 2026 ($Million)
8.6.2. Market Revenue and Forecast By Application, 2015 - 2026 ($Million)
8.6.3. Market Revenue and Forecast By Technique, 2015 - 2026 ($Million)
8.7. Rest of Europe
8.7.1. Market Revenue and Forecast By Product, 2015 - 2026 ($Million)
8.7.2. Market Revenue and Forecast By Application, 2015 - 2026 ($Million)
8.7.3. Market Revenue and Forecast By Technique, 2015 - 2026 ($Million)

CHAPTER 9. ASIA-PACIFIC DOWNSTREAM PROCESSING MARKET BY COUNTRY

9.1. Asia-Pacific Downstream Processing Market Revenue and Growth Rate, 2015 - 2026 ($Million)
9.2. Asia-Pacific Downstream Processing Market Revenue Share Comparison, 2015 amp; 2026 (%)
9.3. China
9.3.1. Market Revenue and Forecast By Product, 2015 - 2026 ($Million)
9.3.2. Market Revenue and Forecast By Application, 2015 - 2026 ($Million)
9.3.3. Market Revenue and Forecast By Technique, 2015 - 2026 ($Million)
9.4. Japan
9.4.1. Market Revenue and Forecast By Product, 2015 - 2026 ($Million)
9.4.2. Market Revenue and Forecast By Application, 2015 - 2026 ($Million)
9.4.3. Market Revenue and Forecast By Technique, 2015 - 2026 ($Million)
9.5. India
9.5.1. Market Revenue and Forecast By Product, 2015 - 2026 ($Million)
9.5.2. Market Revenue and Forecast By Application, 2015 - 2026 ($Million)
9.5.3. Market Revenue and Forecast By Technique, 2015 - 2026 ($Million)
9.6. Australia
9.6.1. Market Revenue and Forecast By Product, 2015 - 2026 ($Million)
9.6.2. Market Revenue and Forecast By Application, 2015 - 2026 ($Million)
9.6.3. Market Revenue and Forecast By Technique, 2015 - 2026 ($Million)
9.7. South Korea
9.7.1. Market Revenue and Forecast By Product, 2015 - 2026 ($Million)
9.7.2. Market Revenue and Forecast By Application, 2015 - 2026 ($Million)
9.7.3. Market Revenue and Forecast By Technique, 2015 - 2026 ($Million)
9.8. Rest of Asia-Pacific
9.8.1. Market Revenue and Forecast By Product, 2015 - 2026 ($Million)
9.8.2. Market Revenue and Forecast By Application, 2015 - 2026 ($Million)
9.8.3. Market Revenue and Forecast By Technique, 2015 - 2026 ($Million)

CHAPTER 10. LATIN AMERICA DOWNSTREAM PROCESSING Market BY COUNTRY

10.1. Latin America Downstream Processing Market Revenue and Growth Rate, 2015 - 2026 ($Million)
10.2. Latin America Downstream Processing Market Revenue Share Comparison, 2015 amp; 2026 (%)
10.3. Brazil
10.3.1. Market Revenue and Forecast By Product, 2015 - 2026 ($Million)
10.3.2. Market Revenue and Forecast By Application, 2015 - 2026 ($Million)
10.3.3. Market Revenue and Forecast By Technique, 2015 - 2026 ($Million)
10.4. Argentina
10.4.1. Market Revenue and Forecast By Product, 2015 - 2026 ($Million)
10.4.2. Market Revenue and Forecast By Application, 2015 - 2026 ($Million)
10.4.3. Market Revenue and Forecast By Technique, 2015 - 2026 ($Million)
10.5. Rest of Latin America
10.5.1. Market Revenue and Forecast By Product, 2015 - 2026 ($Million)
10.5.2. Market Revenue and Forecast By Application, 2015 - 2026 ($Million)
10.5.3. Market Revenue and Forecast By Technique, 2015 - 2026 ($Million)

CHAPTER 11. MIDDLE EAST DOWNSTREAM PROCESSING Market BY COUNTRY

11.1. Middle East Downstream Processing Market Revenue and Growth Rate, 2015 - 2026 ($Million)
11.2. Middle East Downstream Processing Market Revenue Share Comparison, 2015 amp; 2026 (%)
11.3. Saudi Arabia
11.3.1. Market Revenue and Forecast By Product, 2015 - 2026 ($Million)
11.3.2. Market Revenue and Forecast By Application, 2015 - 2026 ($Million)
11.3.3. Market Revenue and Forecast By Technique, 2015 - 2026 ($Million)
11.4. UAE
11.4.1. Market Revenue and Forecast By Product, 2015 - 2026 ($Million)
11.4.2. Market Revenue and Forecast By Application, 2015 - 2026 ($Million)
11.4.3. Market Revenue and Forecast By Technique, 2015 - 2026 ($Million)
11.5. Rest of Middle East
11.5.1. Market Revenue and Forecast By Product, 2015 - 2026 ($Million)
11.5.2. Market Revenue and Forecast By Application, 2015 - 2026 ($Million)
11.5.3. Market Revenue and Forecast By Technique, 2015 - 2026 ($Million)

CHAPTER 12. AFRICA DOWNSTREAM PROCESSING Market BY COUNTRY

12.1. Africa Downstream Processing Market Revenue and Growth Rate, 2015 - 2026 ($Million)
12.2. Africa Downstream Processing Market Revenue Share Comparison, 2015 amp; 2026 (%)
12.3. South Africa
12.3.1. Market Revenue and Forecast By Product, 2015 - 2026 ($Million)
12.3.2. Market Revenue and Forecast By Application, 2015 - 2026 ($Million)
12.3.3. Market Revenue and Forecast By Technique, 2015 - 2026 ($Million)
12.4. Egypt
12.4.1. Market Revenue and Forecast By Product, 2015 - 2026 ($Million)
12.4.2. Market Revenue and Forecast By Application, 2015 - 2026 ($Million)
12.4.3. Market Revenue and Forecast By Technique, 2015 - 2026 ($Million)
12.5. Rest of Africa
12.5.1. Market Revenue and Forecast By Product, 2015 - 2026 ($Million)
12.5.2. Market Revenue and Forecast By Application, 2015 - 2026 ($Million)
12.5.3. Market Revenue and Forecast By Technique, 2015 - 2026 ($Million)

CHAPTER 13. COMPANY PROFILE

13.1. General Electric Company (GE Healthcare)
13.1.1. Company Snapshot
13.1.2. Overview
13.1.3. Financial Overview
13.1.4. Type Portfolio
13.1.5. Key Developments
13.1.6. Strategies
13.2. Thermo Fisher Scientific Inc.
13.2.1. Company Snapshot
13.2.2. Overview
13.2.3. Financial Overview
13.2.4. Type Portfolio
13.2.5. Key Developments
13.2.6. Strategies
13.3. Merck KGaA (Merck Millipore)
13.3.1. Company Snapshot
13.3.2. Overview
13.3.3. Financial Overview
13.3.4. Type Portfolio
13.3.5. Key Developments
13.3.6. Strategies
13.4. Sartorius Stedim Biotech S.A.
13.4.1. Company Snapshot
13.4.2. Overview
13.4.3. Financial Overview
13.4.4. Type Portfolio
13.4.5. Key Developments
13.4.6. Strategies
13.5. Danaher Corporation
13.5.1. Company Snapshot
13.5.2. Overview
13.5.3. Financial Overview
13.5.4. Type Portfolio
13.5.5. Key Developments
13.5.6. Strategies
13.6. Dover Corporation
13.6.1. Company Snapshot
13.6.2. Overview
13.6.3. Financial Overview
13.6.4. Type Portfolio
13.6.5. Key Developments
13.6.6. Strategies
13.7. Repligen
13.7.1. Company Snapshot
13.7.2. Overview
13.7.3. Financial Overview
13.7.4. Type Portfolio
13.7.5. Key Developments
13.7.6. Strategies
13.8. Boehringer Ingelheim International GmbH
13.8.1. Company Snapshot
13.8.2. Overview
13.8.3. Financial Overview
13.8.4. Type Portfolio
13.8.5. Key Developments
13.8.6. Strategies
13.9. 3M Company
13.9.1. Company Snapshot
13.9.2. Overview
13.9.3. Financial Overview
13.9.4. Type Portfolio
13.9.5. Key Developments
13.9.6. Strategies
13.10. Eppendorf AG
13.10.1. Company Snapshot
13.10.2. Overview
13.10.3. Financial Overview
13.10.4. Type Portfolio
13.10.5. Key Developments
13.10.6. Strategies
13.11. Corning Corporation
13.11.1. Company Snapshot
13.11.2. Overview
13.11.3. Financial Overview
13.11.4. Type Portfolio
13.11.5. Key Developments
13.11.6. Strategies
13.12. Ashai Kasei
13.12.1. Company Snapshot
13.12.2. Overview
13.12.3. Financial Overview
13.12.4. Type Portfolio
13.12.5. Key Developments
13.12.6. Strategies
13.13. Lonza Group Ltd
13.13.1. Company Snapshot
13.13.2. Overview
13.13.3. Financial Overview
13.13.4. Type Portfolio
13.13.5. Key Developments
13.13.6. Strategies
13.14. Ferner PLC
13.14.1. Company Snapshot
13.14.2. Overview
13.14.3. Financial Overview
13.14.4. Type Portfolio
13.14.5. Key Developments
13.14.6. Strategies
13.15. Others
13.15.1. Company Snapshot
13.15.2. Overview
13.15.3. Financial Overview
13.15.4. Type Portfolio
13.15.5. Key Developments
13.15.6. Strategies

CHAPTER 14. RESEARCH APPROACH

14.1. Research Methodology
14.1.1. Initial Data Search
14.1.2. Secondary Research
14.1.3. Primary Research
14.2. Assumptions and Scope

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Last Updated: 18-Jul-2019