Hypercalcemia Treatment Market Size Is Anticipated To Reach US$ 28,060.0 Million at a CAGR of 11.7% By 2027 | Says, Coherent Market Insights
Excess parathyroid hormone (PTH) released by the parathyroid glands is the most common cause of high calcium blood levels. This can cause enlargement of one or more parathyroid glands. Denosumab is a humanized monoclonal antibody used in hypercalcemia treatment. It inhibits the receptor activator of nuclear factor-κB ligand (RANKL).
In 2018, the global hypercalcemia treatment market was valued at US$ 10,696.6 million and is expected to surpass US$ 28,060.0 million by 2027.
Global Hypercalcemia Treatment Market: Drivers
The most prominent cause of high calcium levels in the blood is multiple myeloma. Thus, a high incidence of multiple myeloma is estimated to drive the global hypercalcemia treatment market growth. For example, according to the American Cancer Society, around 32,270 new cases of multiple myeloma are expected to be diagnosed in 2020 in the U.S. (17,530 men and 14,740 women).
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Furthermore, the availability of appropriate drug therapy alternatives to surgery are also expected to propel the market growth. Bisphosphonates normalize serum calcium levels in the blood in more than 70% of patients with hypercalcemia of malignancy within a period of 2 to 6 days of the treatment. Bisphosphonates significantly reduce skeletal-related events (SREs).
Global Hypercalcemia Treatment Market: Opportunities
Precise and definitive diagnosis of severe symptomatic hypercalcemia remains challenging. Etiological discussion of the non-malignant causes of parathyroid hormone-suppressed hypercalcemia can address the issue in this regard.
Global Hypercalcemia Treatment Market: Restraints
The distribution of hypercalcemia drugs has to face logistical challenges in terms of manufacturers finding suitable channels such as drug stores and independent pharmacies to stock these medicines. The above factor is expected to hinder the growth of the market.
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In 2018, based on drug type, the bisphosphonates segment was estimated to account for US$ 7,306.2 million in terms of value. The segment is expected to witness a CAGR of 11.7% during the forecast period (2019 – 2017) and is expected to reach US$ 19,798.3 million by 2027. Bisphosphonates are the standard of care in the management of cancer-associated hypercalcemia. Bisphosphonates such as Zoledronic Acid, Clodronate, and others are commonly prescribed drugs for hypercalcemia management. High preference for these medicines is expected to propel the segment growth during the forecast period.
In 2018, based on the distribution channel, the hospital segment dominated the global hypercalcemia treatment market, accounting for 39.0% of market share in terms of value, followed by clinics and Independent Pharmacy and Drug Stores, respectively. Patients go to the hospital mainly for the treatment of diseases like hyperkalemia. Furthermore, hospitals treat many cancer patients who may also be suffering from hypercalcemia. These above-mentioned factors are expected to propel the segment growth during the forecast period.
In 2018, the North America dominated the global hypercalcemia treatment market, accounting for 45.5% of the market share in terms of value, followed by Europe. Factors such as the presence of leading manufacturers, favorable reimbursement, and high patient population are also expected to propel the growth of the region during the forecast period.
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Synthetic implants can be used to detect hypercalcemia linked with cancer. For example, in May 2018, researchers at ETH Zurich (Switzerland) and the University of Basel (Switzerland) reported an early warning system that consists of an encapsulated gene network integrated into human body cells implanted under the skin, which monitor blood calcium levels.
Lithium can adversely impact the parathyroid glands and causes long term thyroid problems. Furthermore, lithium-induced hyperparathyroidism is expected to occur in women four times more than in men.
Global Hypercalcemia Treatment Market: Competitive Landscape
Major players operating in the global hypercalcemia treatment market are Bayer Pharma AG, Sun Pharmaceutical Industries Ltd., Mylan N.V., Pfizer Inc., Amgen Inc., Novartis AG, Dr. Reddy’s Laboratories Ltd., Cipla Inc., and XOMA Corporation.
Global Hypercalcemia Treatment Market: Key Development
January 2019: Teva Pharmaceutical Industries Limited announced that it has resolved its ongoing dispute with Amgen over Teva’s generic cinacalcet HCl product.
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- By Product Type
- Zoledronic Acid
- By Distribution Channel
- Independent Pharmacy & Drug Stores
- By Region
- North America
- Latin America
- Asia Pacific
- Middle East
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