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Proteinase K Market to Reach a Market Valuation of US$ 35.5 Million by 2027 | Proteinase K Market Global Trends, Industry Size, Share, Growth Insight and Forecast to 2027

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Proteinase K is referred as a proteolytic enzyme that cleaves peptide bonds next to the carboxylic group of aliphatic and aromatic amino acids. It is utilized in biological samples for digestion of proteins.

The global proteinase K market is estimated to be valued at US$ 21.9 Mn in 2019, and is expected to surpass US$ 35.5 Mn by the end of 2027

Global Proteinase K Market: Drivers

The growth of the market is attributed to increasing number of funding for R&D in molecular biology. For instance, in February 2020, Princeton University funded six research discoveries that include, a research focused on developing a new approach to control fat metabolism through the development of drugs that target an enzyme called Nocturnin, which regulates fat storage and energy usage.

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Global Proteinase K Market: Opportunities

The increasing adoption of proteinase K in R&D of rare diseases is one of the major factor that is expected to offer lucrative growth opportunities for players operating in the global proteinase K market. For instance, in April 2019, researchers from Scripps Research reported that labelling light chains with fluorophores and coupling shape changes to cleavage by proteinase K in order to identify a group of small molecules that prevent structural changes to proteins that that cause AL amyloidosis, a rare and progressive disease.

Global Proteinase K Market: Restraints

However, low thermal stability of proteinase K limits the hydrolysis and aminolysis reactions in industrial processes, which is expected to hamper growth of the market over the forecast period.

Key Takeaways:

On the basis of form, purification of DNA & RNA segment in the global proteinase K market was valued at US$ 11.5 Mn in 2018 and is expected to reach US$ 20.5 Mn by 2027, exhibiting a CAGR of 6.5% during the forecast period. The growth of the segment is attributed to rising application of purified DNA and RNA in various molecular biology processes. These processes often include development of novel gene therapies which are increasingly being researched across various research institutes.

Among end user, biotechnology companies segment held a dominant position in the global proteinase K market in 2018, accounting for 45.5% market share in terms of value, followed by contract research organizations and academic institutes segments, respectively. The growth of the segment is attributed to biotechnology companies that are engaged in research and development of novel DNA and RNA based therapies for treatment of various genetic, and rare diseases, and these process involve extensive usage of chemicals such as Proteinase K.

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Among regions, North America held a dominant position in the global proteinase K market in 2018, accounting for 36.9% market share in terms of value, followed by Europe. The regional growth is owing to presence of well-established large scale as well as small and medium scale biotechnology organizations in the region, who are indulged in research and development novel gene therapies.

Market Trends

The market is witnessing rising application of proteinase K in DNA extraction from food samples, in order to test the presence of genetically modified organisms. One such application involves homogenization of frozen northern shrimps in 200 µl of water and blending the homogenates with Lysis Solution CBV and Proteinase K. Thus increasing usage of proteinase K is expected to drive the market growth over the forecast period.

Major players in the operating in the market are focusing on partnerships, in order to expand their product portfolio and to strengthen their position in the global market. For instance, in July 2018, Norgen Biotek Corp. entered into a partnership with Diversigen Inc. to provide a combined offering from sample collection, ambient temperature stabilization for transport and logistics for all types of microbiome samples and formats, and the purification of high quality, inhibitor-free nucleic acids from these samples.

Global Proteinase K Market: Competitive Landscape

Key players operating in the global proteinase K market include Thermo Fisher Scientific Inc., Merck KGaA, Qiagen N.V., F. Hoffmann-La Roche Ltd., New England Biolabs, Worthington Biochemical Corporation, Norgen Biotek Corp., BIORON GmbH, Sisco Research Laboratories Pvt. Ltd., Bioline (Meridian Biosciences Inc.), and Promega Corporation.

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Global Proteinase K Market: Key Developments

Major market players are focusing on expanding their geographical presence. For instance, in July 2019, New England Biolabs started New England Biolabs Australia Pty Ltd. in Melbourne, Australia, in order to extend its global subsidiary network.


  • By Form
    • Lyophilized Powder Form
    • Liquid Form
  • By Application
    • Purification of DNA & RNA
    • In situ Hybridization
    • Mitochondria Isolation
    • Enzyme Removal
  • By End-User
    • Contract Research Organization
    • Academic Institutes
    • Biotechnology Companies
    • Diagnostic Laboratories
  • By Region
    • North America
    • Latin America
    • Europe
    • Asia Pacific
    • Middle East
    • Africa

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Last Updated: 27-Jul-2020