ALK Positive Lung Cancer Treatment Market Size Estimation, Future Growth Insights, Share Analysis, Key Profile, Dynamics and Business Overview By 2026
SEATTLE, April 12, 2021, (PHARMIWEB) — ALK Positive Lung Cancer Treatment Market – Insights
Anaplastic Lymphoma Kinase (ALK) positive lung cancer is caused due to mutation of ALK, a gene that aids introduction of proteins. In the mutation, fusion of two genes called as ALK and Echinoderm Microtubule-associated protein Like 4 (EML4) leads to gene rearrangement. The ALK gene fusion was first reported in 2007, in non-small cell lung cancer (NSCLC) patients.
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Increasing R&D of new drugs to augment growth of the market
Increasing focus of market players in R&D and approval of new drugs is expected to boost growth of the global ALK positive lung cancer treatment market. For instance, in August 2018, China National Drug Administration (CNDA) approved Alecensa (alectinib) of F. Hoffmann-La Roche Ltd. for the treatment of ALK-positive lung cancer. Moreover, CNDA also granted marketing authorization for Alecensa (alectinib), as monotherapy treatment for patients with ALK-positive and advanced non-small cell lung cancer (NSCLC).
Increasing resistance to drugs to hinder growth of the market
Increasing resistance to drugs is expected to hamper growth of the ALK positive lung cancer treatment market. For instance, according to an Oncology Live February 2018 report, major challenge in drug development is rapid growth in resistance, which is responsible for slow patient recovery from disease. Moreover, according to an article published in Cancers journal, in August 2017, the mechanisms for resistance in drugs is tyrosine kinase mutations and Epidermal Growth Factor Receptor (EGFR) activation. These bypass mechanisms of resistance are aggravating tumor cells.
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North America is expected to witness significant growth in the market
Increasing number of clinical trials is expected to boost growth of the market in North America. For instance, TP Therapeutics, Inc. is undergoing clinical trial for TPX-0005 drug for the treatment of ALK mutations. The study is expected to complete in December 2021.
Increasing prevalence of lung cancer is expected to propel growth of the market in Asia Pacific. For instance, according to an article published in Eastern Journal of medical Sciences 2017, lung cancer contributes around 6.8% of all cancers in India, representing the significant burden of lung cancer on the country, which is contributing towards cancer morbidity and mortality.
ALK Positive Lung Cancer Treatment Market: Competitive Landscape
Major players operating in the ALK positive lung cancer treatment market include, Eli Lilly and Company, F. Hoffmann-La Roche Ltd., Bristol-Myers Squibb Company, Pfizer Inc., Novartis AG, and TP Therapeutics, Inc.
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ALK Positive Lung Cancer Treatment Market – Taxonomy
- By Drug
- By Distribution Channel
- Hospital Pharmacies
- Retail Pharmacies
- By Region
- North America
- Asia Pacific
- Latin America
- Middle East
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