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Serial health-tech entrepreneur Claudio D’Angelo launches new digital health and med-tech investment management firm Spex Capital

Serial health-tech entrepreneur Claudio D’Angelo launches new digital health and med-tech investment management firm Spex Capital 


Thanks to an ongoing relationship with MedCity, Spex Capital benefits from an affiliation to the NHS in England. The firm boasts a multidisciplinary investment and advisory team of the highest calibre with combined financial and medical industry experience  


Spex Capital will review and assess hundreds of early-stage companies every year, looking for the most promising candidates and offering tickets up to £5,000,000 



London, 29th April 2021 - Claudio D’Angelo, former co-founder and co-managing partner of Ryse Asset Management, today announces the launch of his latest venture – an investment management firm designed to help digital healthcare and med-tech start-ups deliver breakthroughs in healthcare systems.  


With an initial fundraising target of £100m and a robust starting portfolio of seven companiesSpex Capital will identify, support, and invest in early-stage digital health companies, allowing them to commercialise and scale within the NHS and other healthcare delivery systems on a global scale. The firm will invest in early stage and series A / B companies, offering tickets up to £5,000,000. 


Success at its core  


Spex Capital kicks off with a strong team of twelve in place, made up of five investment team members and seven senior advisors. The team of senior advisors has been carefully chosen on the calibre of their backgrounds and complementary skills in the sector.  


Claudio D’Angelo has personally made nine investments in seven target companies which now form Spex Capital’s current portfolio. The majority of these technologies have proven incredibly resilient to the current pandemic environment, have gained market share and are accelerating fund raising for further technological and geographical expansion.  


A unique model  


Based in London and leveraging its global reach in the sector, Spex Capital will be unique in its genre for the international proposition it offers to health-tech entrepreneurs and investors. Ahead of launch, the firm has already established a world-class ecosystem via partnerships and relationships with accelerators and incubators, universities, hospitals, embassies, chambers of commerce, trade bodies, payors and healthcare systems across all continents to source the highest quality technologies worldwide.   


Through its central hub in London and thanks to its ongoing relationship with MedCity, Spex Capital benefits from connections to the NHS in England and several other stakeholders in this vertical.  


Claudio D’Angelo, co-founder and managing director of Spex Capitalcomments “Spex, from specere, latin verb for 'to look at’, defines who we are. As thorough observers, we analyse potential investee companies scrupulously, carrying out a detailed due diligence in order to efficiently select and invest in them. Following my experience with Ryse Asset Management, I decided to launch a more ambitious venture both in terms of scale and geographical focus. 

Many innovative ventures in the digital health and med-tech sector don't get access to the appropriate opportunities in their early stages due to lack of funds and investors tending to favour business models with a longer track record. There is however, an incredible pool of talent with unexpressed potential. This is where Spex comes in. 

Specialised in advancing disruptive early-stage ventures, our goal is to deliver breakthroughs in healthcare systems globally. 


Thank you MedCity for the support and thank you also to the incredible team that has chosen to join me in this exciting journey”. 

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Last Updated: 30-Apr-2021