Defence Therapeutics Inc.: Defence's AccumTM-HPV vaccine formulation (AccuVAC-PT009) activates a 36-fold higher humoral response compared to Gardasil-9
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Defence's AccumTM-HPV vaccine formulation (AccuVAC-PT009) activates a 36-fold higher humoral response compared to Gardasil-9
Vancouver, BC, Canada, January 26th, 2022 - Defence Therapeutics Inc. ("Defence" or the "Company"), a pre-clinical biotechnology company developing various immune-oncology products, is pleased to announce the development of AccuVAC-PT009, a new protein-based HPV vaccine, leading to a humoral response bypassing Gardasil-9 (Merck) immunogenicity in animals.
ACCUMTM is a platform technology 100% owned by Defence Therapeutics. ACCUMTM is an enabling technology as it can be used to enhance the intracellular accumulation of various proteins of pharmacological interests into any target cells. As such, it is currently used by Defence for the development of several anti-cancer and COVID vaccines, as well as for the improvement of approved or in development antibody-drug conjugates.
"We are extremely proud to demonstrate again how ACCUMTM can be exploited and applied to significantly improve any protein-based vaccine. Not only can this vaccine have a tremendous impact on improving the immunogenicity of the commercialized Gardasil-9, but it can in addition lower the dosing regimen (at least by 10-fold) yet triggering similar or more potent humoral response", says Mr. Plouffe, the CEO of Defence.
According to Fortune Business Insights, the global HPV vaccine market size was valued at $3.80 Bn in 2019 & is projected to reach $12.69 Bn by 2027, with a CAGR of 16.3%.
Defence Therapeutics is currently working on various scenarios. Although its initial intent is to pursue the development of its AccuVAC-PT009 HPV vaccine candidate or even adding other subtypes currently not covered by Gardasil-9, the company is actively looking for to establish partnerships with major pharmaceuticals players to bring forward its vaccine portfolio.
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26.01.2022 Dissemination of a Corporate News, transmitted by DGAP - a service of EQS Group AG.
|Company:||Defence Therapeutics Inc.|
|1680 - 200 Burrard St|
|Listed:||Regulated Unofficial Market in Frankfurt, Stuttgart; Toronto|
|EQS News ID:||1272760|
|End of News||DGAP News Service|