Isomerase and BugBiome Partner to Advance Sustainable Crop Protection via Targeted Novel Bioinsecticides

Isomerase has formed a strategic partnership with BugBiome, which is focused on the discovery of novel targeted bioinsecticides via insect behavioural screening. This collaboration aims to accelerate the discovery of bioactive compounds from unexplored microbial sources, combining Isomerase’s extensive collection of actinomycetes with BugBiome’s insect behavioural screening platform, AvidX, to develop sustainable agricultural solutions.

As part of this partnership, BugBiome will gain non-exclusive research access to Isomerase’s collection of approximately 7,000 proprietary actinomycete strains. These strains have demonstrated a remarkable range of activity, having been tested against a variety of pathogens and evaluated for various biological activities, including cytostatic, enzyme inhibition, and virus inhibition. The strains are part of Isomerase’s extensive microbial collection, which includes nearly 20,000 prokaryotic and eukaryotic isolates. BugBiome will evaluate the actinomycete strains to identify actives that effectively deter important crop pests while protecting beneficial organisms and minimizing environmental impact.

BugBiome has the option to secure exclusive commercial rights to strains of particular interest. Financial terms of the deal are not being disclosed.

This collaboration underscores the shared commitment of both companies to reduce reliance on synthetic pesticides, protect ecosystems, and deliver innovative solutions to meet global agricultural challenges.

Dr Alicia Showering. CEO and co-founder of BugBiome, said "We are thrilled to partner with Isomerase and gain access to their extensive collection of over 7,000 high-quality actinomycete strains. This partnership complements BugBiome’s in-house bioprospecting efforts, and we’re excited about its potential to generate targeted bioinsecticides that can protect significant crops globally."

About BugBiome

BugBiome’s mission is to address agricultural pest protection with naturally derived solutions, leveraging microbes as a sustainable source of alternatives to synthetic and bio-accumulative chemicals. The company’s innovative insect behavioural screening platform decodes complex insect-microbe interactions, identifying microbial solutions that outsmart pests naturally without harming beneficial insects or the environment. Based in Cambridge UK, it is backed by Cambridge Angels, Discovery Park Ventures and IndieBio/SOSV. For more details please contact alicia@bugbiome.com, go to www.bugbiome.com or follow BugBiome on LinkedIn.

About Isomerase

At Isomerase, we pride ourselves on being at the forefront of microbial and process discovery and development. Our expertise spans protein discovery and engineering, strain engineering, USP/DSP development, biocatalysis, and more. With a robust portfolio of technology IP and a highly experienced technical and leadership team, we have a proven track record of successful collaborations with leading pharmaceutical and biotech companies.

Our mission is to support our partners in transforming early-stage concepts into commercially viable products, driving progress from initial discovery through to scaled manufacture. To learn more about Isomerase’s strain collection, visit this link Proprietary Strains | Biology | Technology - Isomerase. For more information about our services and how we can support your project, contact us at bd@isomerase.com, visit our website or follow us on LinkedIn.