Model N Manages $1.3 Trillion in Gross Revenue for Life Sciences Customers

Milestone reflects growing demand for greater control across pricing, revenue, and compliance as life sciences manufacturers face rising gross-to-net complexity

REDWOOD CITY, Calif., April 21, 2026 — Model N, the leading end-to-end commercialization, revenue optimization, and compliance platform for life sciences companies, announced that it now manages $1.3 trillion in gross revenue for pharmaceutical and medical technology manufacturing customers.

The momentum reflects Model N’s significant role in helping life sciences companies expand market access, support revenue optimization, and maintain compliance in complex global markets. This comes as life sciences manufacturers face rising gross-to-net complexity, with new pressures tied to Medicare price negotiations, 340B compliance, and the need to prepare for potential future pricing models such as most-favored-nation (MFN).

“This milestone reflects the critical role Model N plays in helping life sciences manufacturers operate with confidence,” said Bret Connor, CEO of Model N. “As gross-to-net complexity and regulatory change accelerate, manufacturers are turning to trusted partners that can connect pricing, revenue, and compliance, so they can make informed decisions and execute at scale.”

Rising complexity continues to put pressure on gross-to-net performance across the life sciences industry. According to Model N’s State of Revenue Report, 99% of industry leaders say gross-to-net has become more complex, reinforcing the need for integrated, data-driven revenue operations.

Recent Highlights:

Business Momentum and Customer Impact as of April 2026

• $25 billion in projected customer savings and more than 20x ROI, based on Model N’s customer value analyses.

• Numerous new customers added since October 2025, including Altera, Aptiv Global Operations Limited, Bavarian Nordic, and Cytokinetics Inc.

Product Innovation and Strategic Partnerships

• Expanded global market access through a strategic partnership with CCX.
• Launched Data nSights, an AI-ready integrated data and analytics solution to support data-driven decision-making.
• Expanded agentic workflows across pricing, deal execution, and gross-to-net to optimize workflows while maintaining governance and control.
• Up to 20% of discount-dollar requests are disputed by customers using Validata Vigilance, helping them recapture revenue so they can reinvest in innovation. 

“We’re seeing a shift toward operational readiness as a competitive advantage,” Connor added. “Companies that can connect pricing decisions to downstream impact are better positioned to adapt, maintain compliance, and execute at scale.”

Model N now works with more than 150 companies across 120+ countries. To support that scale, Model N has also expanded its executive leadership team across product, technology, customer success, and finance for its next phase of growth.

For more information about Model N’s solutions, visit www.modeln.com.