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GSK to Invest in UK's Chroma Theraputics

24 Jun 09

GSK and Chroma Therapeutics Limited, have announced a collaboration to develop macrophage-targeted compounds using Chroma’s proprietary esterase-sensitive motif (ESM) technology, which adds amino acid esters to compounds with the aim of targetting the compounds to specific cells in the inflammatory disease process.


Under the terms of the collaboration with GSK’s Centre of Excellence for External Drug Discovery
(CEEDD), Chroma will undertake four discovery and development programmes to identify small molecule therapeutics, including its macrophage-targeted HDAC inhibitor programme for inflammatory disorders such as rheumatoid arthritis. Chroma will receive a significant up-front cash payment and, in addition, GSK will invest in Chroma’s Series D equity financing, announced separately by Chroma today.

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