BEGIN:VCALENDAR PRODID:-//github.com/rianjs/ical.net//NONSGML ical.net 4.0//EN VERSION:2.0 BEGIN:VEVENT DESCRIPTION:The 5th Digital DDR\, ATR &\; PARP Inhibitors Summit is com ing at a timely inflection point within this field. With Wee1 &\; ATR approvals on the horizon and countless novel targets currently undergoing exciting pre-clinical validation\, this unique &\; highly anticipated meeting unites the world experts in DDR inhibition to propel this space through the barriers it faces to clinical breakthrough.\n\nThis industry- led forum once again evolves to reflect progress in the DDR therapies fie ld with focused content on:\n\nPARP Inhibition: Next-Gen PARPi’s\, PARP R esistance &\; the Future of PARP InhibitorsDeveloping Clinically Succe ssful Wee1 &\; ATR Inhibitors for Cancer TherapyDeveloping Predictive Pre-Clinical Models in DDR to Achieve Human-Specific TranslationNovel Met hodologies &\; Imaging Technologies to Revolutionize Pathway Understan ding\, Compound Optimization &\; Clinical TranslationEstablishing a Pr e-Clinically Validated Novel Target: PolθIdentifying Reliable DDR/HR Tumo r BiomarkersExploring the Emerging Targets in the DDR Pathway: Strategy\, Execution\, Development and PromiseManaging Toxicity - Dose\, Delivery\, Scheduling\, Patient Selection\, &\; Stratification - Managing the Th erapeutic Window &\; Treatment RegimesNext Steps in Combination Approa ches - to Heighten Drug Effect &\; Overcome Resistance - What is the F uture of the Field?\n DTEND:20220127T170000 DTSTAMP:20260512T232942Z DTSTART:20220125T090000 LOCATION:Online\, 1 Avenue de Lafayette\, Boston\, Massachusetts\, 02111\, SEQUENCE:0 SUMMARY:The 5th Digital DDR\, ATR &\; PARP Inhibitors Summit is coming at a timely inflection point within this field. With Wee1 &\; ATR appr ovals on th... UID:82acf26c-dffb-4f64-87fa-c513a41ba4bc END:VEVENT END:VCALENDAR