Articles

Pharmacovigilance (PV) is an essential component in the patient safety system to find, evaluate and prevent adverse effects for medicinal products. As the life sciences sector continues to mature beyond national boundaries, pharmaceutical and biotech companies are given a strategic option — to choose global pharmacovigilance consulting services, or local PV partners.
Global vs Local Pharmacovigilance Consulting Partner Pharmacovigilance (PV) is an essential component in the patient safety system to find, evaluate and prevent adverse effects for medicinal products. As the life sciences sector continues to mature beyond national boundaries, pharmaceutical and biotech companies are given a strategic option — to choose global pharmacovigilance consulting services, or local PV partners. Each ap…

Recombinant Human Albumin Injection (Oryza Sativa), or OsrHSA, is a plant-based therapy for hypoalbuminemia (≤30 g/L) in cirrhosis patients, developed by Wuhan Healthgen Biotechnology. Produced from rice grains, it provides a safe alternative to plasma-derived albumin, free from pathogen risks and supply issues. Approved by China's NMPA on July 18, 2025, phase III trials showed non-inferior efficacy in increasing albumin levels and managing ascites. The NCT06355479 study confirmed its safety in decompensated cirrhosis. Hong Kong wholesalers like DengYuePharma specialize in exporting such rare drugs globally, boosting access. This advances sustainable biotech in liver care.
Hypoalbuminemia, characterized by serum albumin levels ≤30 g/L, is a common complication in patients with cirrhosis, of…

A just-published report from a House of Lord Select Committee has highlighted several critical issues facing the UK’s vital life sciences sector. Leading academic Ivan Wall, Professor of Regenerative Medicine at the University of Birmingham, says the report makes a vital contribution to the debate around the UK’s viability to realise its full potential in this key area, but notes its failure to address a critical underpinning element – the need to train a new generation for working in the sector.
A just-published report from a House of Lord Select Committee has highlighted several critical issues facing the UK’s vital life sciences sector. The report follows the news in recent weeks that Merck has scrapped a £1 billion investment in the UK, AstraZeneca has paused projects, and Eli Lilly ha…

Innovation in drug development has never moved faster! New modalities, real-world evidence, complex patient stratification, and AI are reshaping what’s possible. Yet one of the biggest bottlenecks remains stubbornly constant: the fragmented, slow, and opaque way that benefits–risk assessments are built and communicated between pharma innovators and regulatory bodies.
In all honesty, the risk-benefit process for drug approvals has barely evolved in the last twenty years. The emergence of AI has created a huge opportunity for players to disrupt this market and look at ways to transform how new drugs are evaluated and approved. This new type of technology is finally equipping regulators and companies with tools to assess, in real time and from large, diverse data, how likely a drug is t…

Precision-fermented proteins offer the tantalising prospect of radically uncoupling our nutrition from arable land. However, the journey from laboratory titre to multi-kiloton commodity supply chains has many non-trivial hurdles in between.
Protein fermentation describes the microbial population's controlled breakdown and build-up of nitrogenous compounds under specific redox potential, pH balance and substrate limitation constraints. The process generally begins with the extracellular degradation of high molecular weight proteins. Protein hydrolysis by microbial aspartic proteases (fungi) or metalloproteases (bacteria) yields oligopeptides (2–20 residues) that are taken up into the cell via specific oligopeptide permeases. Intracellular di- and tri-peptidases further hydrolyze peptide…

In chemistry, materials science and many industries, polyethylene glycol (PEG) and ethylene glycol (EG) are two very crucial chemicals. Both are structurally similar but very different in terms of physical characteristics, chemical characteristics and functional fields.
Chemical Structure and Molecular Weight Polyethylene Glycol is the polymer form of EG, with its molecular weight varying depending on the degree of polymerization. The molecular weight of PEG generally ranges from hundreds to tens of thousands, while EG has a molecular weight of only 62. This difference in molecular weight leads to significant differences in their physical properties and applications. The polymer structure of PEG gives it higher viscosity and better biocompatibility, whereas EG's low molecular weight r…

In today’s biotech landscape, quality is essential. Good Manufacturing Practice (GMP) guidelines are the cornerstone of safe, effective, and consistent pharmaceutical production. For therapeutics based on peptides or oligonucleotides (TIDES), many of which treat complex or life-threatening conditions, GMP compliance is a foundational element of regulatory approval and patient trust.
Growing Importance of Peptide & Oligonucleotide Therapeutics Peptides and oligonucleotides are transforming modern medicine. Peptide-based drugs have become the fastest-growing segment of chemically synthesized therapeutics, with over 80 approved worldwide, more than 200 in clinical development, and hundreds in preclinical stages (Rossino et al., 2023). Oligonucleotide-based therapies have also seen signi…

In the third quarter of 2025 Coulter Partners drove global executive search for a wide range of life sciences, health, and technology organizations. We successfully placed executives for independent and VC & PE-backed firms, alongside large-cap and mid-cap public companies, filling critical roles across diverse disciplines worldwide.
In the third quarter of 2025, Coulter Partners drove global executive search for a wide range of life sciences, health, and technology organizations. We successfully placed executives for independent and VC & PE-backed firms, alongside large-cap and mid-cap public companies, filling critical roles across diverse disciplines worldwide.   CEO/ C-suite/ Board CEO, Diagnostic & laboratory services (PE-backed), France CEO, Small-molecule therap…

The evolution of China pharmaceutical distributors reflects the nation’s shift toward high-value, globally compliant healthcare exports. From China Medicine Wholesaler networks to HongKong Drug Wholesale Distributor hubs, these enterprises combine scale, precision, and reliability. As global demand for affordable, high-quality medicine continues to grow, collaboration with a reputable China Drug Import and Export Wholesaler or a licensed HongKong Pharmaceutical distributor like HongKong DengYue Medicine offers the best route to sustainable, long-term success.
Introduction: How China Pharmaceutical Distributors Shape Global Trade In the past decade, China pharmaceutical distributors have moved from low-cost suppliers to strategic global partners in healthcare logistics. They not only manufac…

Learn how to create a successful Clinical Development Plan covering Preclinical Development to regulatory approval, ensuring patient safety.
For a drug to be discovered and supplied in the market, it takes 10 to 15 years and costs over $2.6 billion on average. Out of 10,000 compounds that reach early research, only one secures regulatory approval. The life cycle of a drug from research to launch requires the expertise of hundreds of scientists, clinicians, statisticians, regulatory specialists, and extensive animal studies with human clinical trials. Any one error in the whole process can be expensive and time-consuming. A clinical development plan acts as the plan for the whole process, ensuring the proper workflow of the drug discovery.    Clinical Development Plan: An Over…

The global Clinical Laboratory Services Market is projected to reach USD 453.7 billion by 2033, driven by rising diagnostic demand, automation, and personalized medicine advancements.
The clinical laboratory services market is entering a phase of sustained expansion, fueled by evolving healthcare dynamics, technological advances, and rising demand for diagnostics-led care. According to FutureWise Research, the global clinical laboratory services market is estimated at USD 291.37 billion in 2025, with projections to reach USD 453.7 billion by 2033, reflecting a compound annual growth rate (CAGR) of 5.69 % over the forecast period. To Know More: https://www.futurewiseresearch.com/contact.aspx?rpt=9678&type=requestsample This article examines key drivers, segmentation i…

Many “hard” regions are operationally complex, not clinically weak. Sponsors that hire local CRA and regulatory consultants gain language and regulatory fluency on the ground, faster submissions, fewer errors, and stronger site relationships—turning delays into predictable startup.
Early in my career, I was helping coordinate a Phase II oncology trial across multiple time zones. One site, located in Eastern Europe, kept falling behind. The issue wasn’t patient recruitment. It was communication. The sponsor was based in California, the CRA was based in London, and the site team didn’t speak much English. Even simple updates took days. We lost time, strained relationships, and nearly missed key milestones. That experience stuck with me. And it taught me a lesson more sponsors are starting to…

As hurricanes become more frequent in the Southeast, seismic activity challenges facilities in the West, and snowstorms weigh heavily on the North, disaster-resilient cold storage has become a cornerstone of business continuity planning.
Disaster-Resistant Cold Storage: The New Standard for Business Continuity Engineering for Continuity in Extreme Weather By: Oscar Infanzon, Design Engineer & Manager, Amerikooler For many businesses, cold storage protection is as critical as power or shelter during a natural disaster. Walk-in coolers and freezers safeguard everything from food and beverages to vaccines and raw materials. A single breakdown can mean thousands of dollars in lost product, extended interruptions to business, and in some cases, a breakdown of supply chains that communities r…

New technologies, changed requirements in production and ever more frequent product changes, but also more strict specifications with regard to occupational and environmental protection are significantly changing many production processes. Three trends in mechanical process engineering show this by way of example.
Process intensification  Forward-looking technologies in process technology rely on process intensification and thus efficient use of the time, energy and raw materials used in a process. When mixing and dispersing with new optimised processes, the differences with regard to required energy, volume-specific capacity or newly created phase boundaries compared to conventional technologies such as agitators, injectors or High Speed Dissolvers are significant.   With t…

Medical billing is the financial backbone of healthcare, ensuring that doctors and hospitals are paid for their services. This involves converting affected person visits into coverage requirements through accurate coding, verification and inspection. Correct billing keeps the flow of coins steady, reduces errors and helps improve patient interactions. Despite advances in time, challenges remain, including regulatory updates, disclaimers and record security. Many suppliers now outsource billing to professionals for better accuracy, compliance and faster reimbursement. With AI, automation and EHR integration shaping the future, scientific billing is evolving into a smarter, simpler and patient-centric system. When done right, it maintains financial health and adheres to state-of-the-art healthcare.

The global Drug Discovery Services Market is projected to reach USD 68.22 billion by 2033, driven by AI adoption, rising R&D investments, and increased outsourcing in pharmaceutical innovation.
In the rapidly evolving pharmaceutical landscape, drug discovery services have become a pivotal axis around which innovation, efficiency and competitiveness rotate. According to a recent market report by FutureWise, the global Drug Discovery Services Market is projected to grow from US$ 21.4 billion in 2025 to more than US$ 68.22 billion by 2033—signifying a compound annual growth rate (CAGR) of 15.59 %.  To Know More: https://www.futurewiseresearch.com/contact.aspx?rpt=3465&type=requestsample This remarkable forecast underscores a confluence of strategic, technological, and market…

ChatGPT said: A career in clinical research focuses on testing new drugs, treatments, and medical devices to ensure safety and effectiveness before public use. Professionals work in hospitals, research centers, and pharmaceutical companies, managing trials, analyzing data, and ensuring regulatory compliance. Key roles include Clinical Research Coordinator, Clinical Research Associate, Trial Manager, Biostatistician, Data Manager, and Medical Writer. Their responsibilities cover study design, participant recruitment, data analysis, and reporting results. Daily duties involve preparing documentation, maintaining records, and coordinating with regulatory authorities. To start a career in this field, a degree in life sciences or medicine is recommended, along with strong analytical, communication, and organizational skills. Certifications like CCRC or CCRA enhance job prospects.

is transforming the digital display industry by introducing energy-efficient, sustainable, and highly readable solutions. E-paper technology—often referred to as electronic ink or electrophoretic display—mimics the appearance of printed paper and consumes power only when the image changes. This makes it a preferred choice for applications where information updates occur intermittently, such as e-readers, retail shelf labels, digital signage, and wearable devices. With rising global emphasis on sustainability and low-power electronic devices, e-paper displays are being integrated across various industries, including retail, logistics, healthcare, education, and public transportation. These displays not only reduce operational costs but also align with eco-friendly digital transformation initiatives.

Achieve clearer, more radiant skin with REFORM Skincare Anti-Blemish Creme. This hyper pigmentation treatment cream is designed to target dark spots, blemishes, and uneven skin tone, helping you restore your skin’s natural glow. Its gentle yet effective formula works to reduce redness, calm inflammation, and prevent future breakouts, making it ideal for all skin types. As a trusted blemish removal cream and face dark spot remover cream, it gradually fades acne scars, age spots, and discoloration for a smoother, even complexion. Lightweight, fast-absorbing, and dermatologist-approved, this cream is your daily solution for healthy, flawless skin.
Say goodbye to stubborn dark spots and uneven skin tone with REFORM Skincare Anti-Blemish Creme. Specially formulated for all skin types, this hyper…