Articles

Diabetes is a common clinical disease, and with the improvement of living standards, an increase in the number of obese people, and the intensification of aging populations, the incidence of diabetes is increasing year by year.
Diabetes has various types and requires long-term treatment. Antidiabetic drugs are essential for people with the disease. These drugs can be classified into insulin injections and oral antidiabetic medications. Commonly used oral antidiabetic drugs in clinical practice include biguanides (such as metformin), sulfonylurea insulin secretagogues (e.g., glimepiride, glipizide, gliclazide), non-sulfonylurea insulin secretagogues (e.g., repaglinide, nateglinide), α-glucosidase inhibitors (acarbose, voglibose, miglitol), DPP-4 inhibitors (sitagliptin, etc.), and GLP-1 rec…

Nanobodies are the smallest functional single-domain antibodies known to be able to stably bind to antigens, and have unique structural and functional advantages.
What is a Nanobody? The molecular weight of nanobodies is only 12-15 kDa, which retains the antigen binding ability of traditional antibodies. However, nanobodies have higher solubility and stability, and have unique advantages in biological function and biochemical characteristics. Therefore, nanobodies have shown good control effects in disease diagnosis, cancer and infectious diseases. What are Nanobody-Drug Conjugates (NDCs) The development concept of nanobody-drug conjugates (NDCs) is similar to that of antibody drug conjugates (ADC), that is, the antibody in ADC is replaced by a nanobody with higher affinity. Because nanobod…

For a long time, the research and development of each new drug has faced the challenges of high cost and long cycle. In response to these challenges, major pharmaceutical companies have shifted from targeting common diseases to developing drugs for specific diseases. At the same time, these companies are constantly looking for new technologies for new drug development, such as high-throughput screening technology, DNA encoded chemical library, computer-aided drug discovery, and artificial intelligence.
The use of computer simulation for drug development may reduce costs and increase the efficiency and success rate of the drug development process. Since the 1990s, computer methods such as homology modeling, molecular docking, quantitative structure-activity relationship and molecular dynamic…

Cytokinin is a potent growth hormone and is commonly used in plant tissue culture, induction of cell division and shoot proliferation, plant regeneration, and in vitro production of plant secondary metabolites and bioactive molecules.
Introduction of Cytokinin Cytokinin is an organic compound that belongs to the cytokinin family. It is widely used in plant physiology and agriculture due to its beneficial effects on plant growth and yield. Cytokinin is a potent growth hormone and is commonly used in plant tissue culture, induction of cell division and shoot proliferation, plant regeneration, and in vitro production of plant secondary metabolites and bioactive molecules. Cytokinins are a class of natural plant growth regulators that play a crucial role in the regulation of cell divisio…

Organic Field Effect Transistor (OFET) materials have shown great promise for their use in organic bioelectronic devices. These materials offer several advantages that make them attractive for biomedical applications.
What are the Organic Field Effect Transistors (OFETs)? Organic Field Effect Transistors (OFETs) have gained significant attention in recent years due to their unique properties and potential applications in the field of organic electronics. As the demand for flexible and stretchable electronics continues to grow, the development of OFET materials that can withstand mechanical stress and strain becomes crucial. What are the Advancements in Flexible and Stretchable OFET Materials? 1. Elastomeric Substrates: One of the key requirements for achieving flexibility and stretchability…

New technologies are supercharging drug development. AI innovations enable pharmaceutical companies to bring safer, more effective medications to market faster. This new age of medicine creates exciting new possibilities for patients and drug manufacturers, but it also brings new challenges.
New technologies are supercharging drug development. AI innovations enable pharmaceutical companies to bring safer, more effective medications to market faster. This new age of medicine creates exciting new possibilities for patients and drug manufacturers, but it also brings new challenges. The recent surge of highly effective weight loss drugs demonstrates the revenue opportunities and complexities facing drug manufacturers. Drugs such as Ozempic and Wegovy deliver unprecedented benefits, skyrocketin…

Embarking on a systematic literature review is a critical step in evidence synthesis, providing a foundation for robust decision-making in the healthcare landscape. As with most things, there are ways to cut corners on systematic reviews. Sometimes there are true efficiencies to be made. Yet, all compromises have consequences. In this article, we delve into 11 common problems that may arise when cost-cutting compromises the quality of your systematic literature review.
1. Choosing the wrong type of systematic review methodology Selecting the wrong type of methodology for your review can have profound implications. A robust, gold standard Cochrane methodology involves two reviewers at all stages of the review, to avoid bias in the identification and presentation of the evidence, and ensur…

Revenue in Australia’s pharmaceuticals market is projected to reach US$10.16bn in 2024, with the largest market being Oncology Drugs with a projected market volume of US$2.01bn. This revenue is expected to grow at an annual rate of 6.76% from 2024 to 2028, resulting in a market volume of US$13.20bn by 2028.
Revenue in Australia’s pharmaceuticals market is projected to reach US$10.16bn in 2024, with the largest market being Oncology Drugs with a projected market volume of US$2.01bn. This revenue is expected to grow at an annual rate of 6.76% from 2024 to 2028, resulting in a market volume of US$13.20bn by 2028. In this article, we round up 10 of the top pharmaceutical companies driving this growth in Australia, with the leading companies listed on the Australian Securities Exchange in 2023,…

Preparing for a job interview can be a daunting task, especially when it comes to the competitive field of pharmaceutical sales. As a jobseeker, you must demonstrate your expertise, sales acumen, and ability to navigate challenging scenarios in a clear and confident manner. One thing you can do to help you achieve this is to practise answering some of the most commonly asked interview questions in the field, allowing you to refine your answers and ensure they are focused and concise.
Preparing for a job interview can be a daunting task, especially when it comes to the competitive field of pharmaceutical sales. As a jobseeker, you must demonstrate your expertise, sales acumen, and ability to navigate challenging scenarios in a clear and confident manner. One thing you can do to help you achi…

Photoresist resins are often used in conjunction with photosensitive agents and play a crucial role in making photoresist photosensitive.
Photoresist resin, also known as film-forming resin, is an inert polymer matrix. It is the core component of photoresist and constitutes the basic photoresist skeleton. Photoresist resins are often used in conjunction with photosensitive agents and play a crucial role in making photoresist photosensitive. The structures vary from different photoresist resins, which mainly determine the basic properties of the photoresist after exposure, including hardness, flexibility, adhesion, the solubility for specific solvents, optical properties, aging resistance, etching, thermal stability, etc. Resins for G/I-line resists The o-diazonaphthoquinone (DNQ)-phe…

As research in cancer theranostics advances, engineered nanoparticles offer tailored drug delivery and simultaneous diagnosis. DNA and peptide-based supramolecular nanoassemblies present programmable strategies for precise drug delivery. Furthermore, microfluidic technologies have paved the way for improved cancer diagnostics and personalized drug delivery via engineered extracellular vesicles. These innovations collectively demonstrate a multidisciplinary approach, fueling greater optimism for the development of next-generation cancer therapies.
3 Recent Breakthroughs in Cancer Research Cancer continues to be one of the leading causes of mortality worldwide, despite extensive research and medical advancements. However, recent breakthroughs in nanotechnology, molecular biology, and bioengin…

With over 90 pharmaceutical companies operating in the country, including 19 of the world’s top 20 biopharma companies, Ireland is globally recognised as a major player in the life science industry. More than 84,000 highly skilled professionals are directly and indirectly employed in the country’s biopharma sector, working for many of the industry’s leading names such as Novartis, AbbVie, Pfizer, Sanofi, and AstraZeneca who all have operations in Ireland.
With over 90 pharmaceutical companies operating in the country, including 19 of the world’s top 20 biopharma companies, Ireland is globally recognised as a major player in the life science industry. More than 84,000 highly skilled professionals are directly and indirectly employed in the country’s biopharma sector, working for many of the…

The selection and careful inclusion of flavoring agents, buffers, plasticizers, and fragrance agents are crucial elements in the formulation of cosmetics.
Introduction Cosmetic products have become an integral part of our daily lives, enhancing our natural beauty and boosting our self-confidence. Behind every cosmetic product lies a complex formulation consisting of various ingredients. Among these ingredients, flavoring agents, buffers, plasticizers, and fragrance agents play crucial roles in enhancing the user experience and improving the overall quality of the product. Flavoring Agents Flavoring agents are commonly used in lip products, such as lipsticks and lip balms, to add a pleasant taste. These agents, sourced from natural or synthetic origins, provide a tempting sensation when…

Microneedles have gained significant attention in recent years due to their potential applications in various fields such as drug delivery, diagnostics, and tissue engineering.
Introduction Microneedles have gained significant attention in recent years due to their potential applications in various fields such as drug delivery, diagnostics, and tissue engineering. The preparation of microneedles requires precise and efficient technologies to achieve desired features such as size, shape, and mechanical strength. This article provides an overview of different technologies used for microneedle preparation, including 3D printing, etching, photolithography, and micro-electromechanical systems (MEMS) technology. 3D Printing Technology for Microneedle Preparation 3D printing technology offers a pr…

Expandable graphite serves as a crucial component in fire-resistant applications across various industries.
Flame Retardant Properties of Expandable Graphite One of the most renowned characteristics of expandable graphite lies in its exceptional flame retardant properties. When exposed to high temperatures or open flames, this substance undergoes a remarkable transformation. Under these conditions, the layers of graphite expand, forming a highly insulating intumescent barrier. This intumescent mechanism effectively prevents heat transfer, flame propagation, and the release of toxic gases. Consequently, expandable graphite serves as a crucial component in fire-resistant applications across various industries. Notably, when incorporated into polymers, such as polyurethane foams, exp…

Here, we’ve rounded up 7 Sales and Commercial career paths within the life science industry, outlining the key responsibilities of each role.
Here, we’ve rounded up 7 Sales and Commercial career paths within the life science industry, outlining the key responsibilities of each role. Read the full article on PharmiWeb.Jobs.

It is essential to explore EHR capabilities and define usage tips specifically for pharma professionals, as their daily routines and objectives differ significantly from those of clinical personnel.
According to the 2022 studies published in the “Pharmacy” and “Advanced Drug Delivery Reviews” journals, electronic health records software can help pharmacies provide more personalized services and improve the quality of patient care, leading to better patient outcomes and increased revenue. So, how do pharmacists benefit from EHRs and use them at full capacity?  1. Consult patients on medication usage based on EHR data   Extended patients’ health history provides pharmacists with information on patients’ demographic and health conditions that can lead to issues with the prescribed t…

Cobalt carbonate is an important precursor to cobalt oxide, cobalt powder, ceramic additives, organic cobalt compounds, and other products, and its purity determines the properties of downstream products.
Cobalt carbonate is an inorganic compound, the chemical formula is CoCO3, a pink crystalline powder, almost insoluble in water, alcohol, ethyl ether methyl ester, and ammonia, mainly used as a mineral dressing agent, catalyst, camouflage paint pigments, feed, trace fertilizers, ceramics, and raw materials for the production of cobalt oxide. Cobalt carbonate is an important precursor to cobalt oxide, cobalt powder, ceramic additives, organic cobalt compounds, and other products, and its purity determines the properties of downstream products. The products prepared by precipitation of s…

The main function of parathyroid hormone (PTH) is to regulate calcium and phosphorus metabolism in vertebrates, resulting in increased blood calcium levels and decreased blood phosphorus levels. At present, PTH is a large protein drug, and its administration route is still limited to injection due to its poor stability, which causes great inconvenience when administered frequently.
The main function of parathyroid hormone (PTH) is to regulate calcium and phosphorus metabolism in vertebrates, resulting in increased blood calcium levels and decreased blood phosphorus levels. At present, PTH is a large protein drug, and its administration route is still limited to injection due to its poor stability, which causes great inconvenience when administered frequently. Microneedle preparation steps …

Antibacterial, anti-inflammatory, and antiviral drugs are commonly used clinically. However, with the spread and evolution of drug resistance, the efficacy of these drugs, especially antibacterial and antiviral drugs, is declining.
Antibacterial, anti-inflammatory, and antiviral drugs are commonly used clinically. However, with the spread and evolution of drug resistance, the efficacy of these drugs, especially antibacterial and antiviral drugs, is declining. At present, there is no effective means to deal with the problem of drug resistance clinically, and the development of new drugs is urgently needed. Antibacterial Series Antibacterial series can be divided into antifungal drugs and antibacterial drugs. Common antibacterial drugs include β-lactams, aminoglycosides, macrolides, quinolone…