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Top Pharmaceutical Companies in the United States

Top Pharmaceutical Companies in the United States


In this article, we look at nine of the top pharmaceutical companies with headquarters in the United States.
  • Author Company: PharmiWeb
  • Author Name: Lucy Walters
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Editor: Lucy Walters Last Updated: 16-Dec-2022

In this article, we look at nine of the top pharmaceutical companies with headquarters in the United States…

Merck & Co.

Founded over 130 years ago, Merck’s mission is to be the premier research-intensive biopharmaceutical company in the world. They are focused on bringing forward treatments for the world’s most challenging diseases to save and improve lives. Headquartered in New Jersey, Merck has more than 74,000 employees and in 2020 reported worldwide sales of $48 billion.

Johnson & Johnson

Also founded over 130 years ago, Johnson & Johnson is the world’s largest healthcare company, striving to improve access and affordability and create healthier communities for all. Headquartered in New Jersey and with more than 130,000 employees, Johnson & Johnson reported $45.6 billion in worldwide pharmaceutical sales in 2020 and invested more than $12 billion in research and development.

Bristol Myers Squibb

Headquartered in New York, Bristol Myers Squibb is a global biopharmaceutical company discovering, developing, and delivering innovative medicines to tackle serious diseases, particularly in the areas of oncology, immunology, and cardiovascular disease. In 2020, total revenues for the company reached $42.5 billion worldwide.

Gilead Sciences

Founded over 30 years ago, Gilead is a biopharmaceutical company advancing medicines aimed at preventing and treating life-threatening diseases, including HIV, viral hepatitis, and cancer. Headquartered in California, the company operates in more than 35 countries worldwide and reported total revenues of $24.7 billion in 2020, with $5 billion spent on research and development.

Eli Lilly

With headquarters in Indiana, Eli Lilly is a global leader in healthcare, committed to advancing high-quality medicines that meet real needs to improve life for people globally. Founded more than 145 years ago, the company has more than 34,000 employees worldwide, with 8,000 engaged in research and development. In 2020, the company reported total revenues of $24.5 billion.


Founded over 170 years ago, Pfizer is one of the world’s premier biopharmaceutical companies, with a global portfolio covering medicines, vaccines, and some of the world’s best-known consumer health care products. With headquarters in New York, the company has over 78,000 employees globally, and in 2020, total revenues reached $41.9 billion.  


Headquartered in Illinois, AbbVie develops medicines aimed at solving today’s serious health issues, working on therapeutic areas including immunology, oncology, neuroscience, eye care, virology, women’s health, and gastroenterology. With more than 48,000 employees worldwide, the company’s 2020 total revenues reached $45.8 billion.  


Founded in 1980, Amgen is one of the world’s leading biotechnology companies, transforming discoveries into medicines for patients with serious illnesses. Headquartered in California and with around 24,000 employees worldwide, the company reached total revenues of $25.4 billion in 2020.


With headquarters in Illinois, Abbott is a global healthcare leader helping people live better at all stages of life. The company has leading businesses and products across diagnostics, medical devices, nutrition and branded generic medicines. With more than 109,000 employees worldwide, Abbott provides more than 400 million COVID-19 tests in 2020 and achieved worldwide sales of $34.6 billion.


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