Xlife Sciences AG: New project in the portfolio
We are pleased to announce that Xlife Sciences AG has added Araxa Biosciences GmbH to the port-folio.
Araxa Biosciences GmbH
For certain diseases, no potent cure or diagnostics exist. Great hope lays in protein-based pharmaceuticals such as antibody-drug conjugate (ADC) or radioimmunotherapy for cancer. The high biological specificity is a critical advantage compared to typical small synthetic pharmaceutical ingredients; it allows the treatment to focus only on the cancer cells and thereby reducing side effects. Targeted chemical modification is used to enhance the effectiveness, and other characteristics of antibodies. It is also not only one of the most promising, but also, most technical advanced development areas of biotechnology. Most common methods for production of protein-small molecule conjugates suffer from drawbacks such as bulky modifications, restriction of the modification site, complex and inefficient procedures, batch-to-batch variety or a high expenditure of time.
Araxa Biosciences GmbH is a spin-off from Europe's most prestigious life science research institute, the European Molecular Biology Laboratory (EMBL) in Heidelberg. The company aims to develop a technology platform which overcomes all the limitations mentioned above. The concept is based on the precise side-specific injection of synthetic so-called unnatural amino-acids (UAA) in monoclonal antibodies through expansion of the genetic code. The UAA can be connected with active pharmaceutical ingredients or radioisotopes through bioorthogonal click chemistry in an ultrafast and quantitative manner - even inside cells and eventually in future patients. The modular concept allows to independently exchange antibodies or modification, enabling a fast change from nuclear diagnosis to ADC therapy. Araxa Biosciences GmbH will operate as a research and development-focused antibody engineering service provider and will consider developing a proprietary pharmaceuticals pipeline.
Xlife Sciences AG
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Issuer: Xlife Sciences AG
Key word(s): Finance
26.11.2019 Dissemination of a Press Release, transmitted by DGAP - a service of EQS Group AG.
|Company:||Xlife Sciences AG|
|Phone:||0041 44 385 84 60|
|Listed:||Regulated Unofficial Market in Munich|
|EQS News ID:||921357|
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