Exosome Research Collaboration

ReNeuron Group plc (AIM: RENE), a UK-based global leader in the development of cell-based therapeutics, today announces that it has signed a research agreement with an unnamed major pharmaceutical company to explore the potential use of the Company’s proprietary exosomes to deliver novel therapeutics.

The agreement follows the Company’s strategy of collaborating with pharmaceutical and biotechnology companies to use its exosome technology as a novel delivery vehicle.  ReNeuron’s exosomes are derived from its CTX neural stem cell line and have the ability to cross the blood brain barrier and to be manufactured at scale.

The research collaboration will focus on the use of the Company’s exosomes for the delivery of gene silencing sequences created by the pharmaceutical company.  ReNeuron will be responsible for manufacturing exosomes and then loading them with the gene silencing sequences after which the pharmaceutical company will evaluate the loaded exosomes.   ReNeuron will be paid by the pharmaceutical company for manufacturing and loading the exosomes in the initial phase of the collaboration.

This is ReNeuron’s second research collaboration following the signing of an ongoing agreement with a US pharmaceutical company in January 2019.

Commenting on the agreement, Olav Hellebø, Chief Executive Officer of ReNeuron, said: “We are delighted to have signed this latest exosome research collaboration agreement with an experienced leader in the discovery and development of novel gene silencing-based therapeutics. The collaboration is in line with our strategy of collaborating and then out-licensing our proprietary exosome technology as a novel delivery vector and underlines the potential commercial value of these proprietary nanoparticles generated from our CTX neural stem cell line.”