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Marinomed receives FFG funding to research SARS-CoV-2 therapy based on Carragelose®

  • Development of a Carragelose®-containing inhalation solution for therapy of patients suffering from a SARS-CoV-2 infection
  • Available clinical data show that Carragelose®binds previously known coronaviruses and other viruses that trigger respiratory infections
  • Austrian Research Promotion Agency (FFG) funds up to 45% of the planned project volume of over EUR 4 million
  • Vienna General Hospital / Medical University of Vienna are project partners


Vienna, April 28, 2020.Marinomed Biotech AG, a globally active biopharmaceutical company based in Vienna, receives funding from the Austrian Research Promotion Agency (FFG) for the development of a SARS-CoV-2 therapy based on Carragelose®. The aim of the project is to clinically test an inhalation solution with Carragelose®as an acute treatment for viral pneumonia caused by SARS-CoV-2 or other respiratory viruses.


"A causal therapy directly in the lungs can shorten the duration of the disease and thus hospitalization for patients suffering from viral pneumonia, reduce the number of patients in intensive care and thus bring enormous benefits for patients and the health system," explains Eva Prieschl-Grassauer, Chief Scientific Officer of Marinomed. The patented Carragelose®developed by Marinomed is one of the very few active ingredients with clinical data from patients who have been infected with previously circulating coronaviruses. In 2014, an analysis of coronavirus infected patients showed that the duration of disease was reduced by more than 3 days in the Carragelose®treated group when compared to patients treated with placebo. Marinomed CSO Eva Prieschl-Grassauer: “We can now capitalize on this strong basis. Due to the broad effectiveness of Carragelose®, we are confident that we can also achieve good results with the current pandemic coronavirus.” Within a year, data should be available clarifing whether the Carragelose®inhalation solution is safe and its use in patients is a health improvement compared to a placebo.


In the current project, the tolerance of the Carragelose®inhalation solution will be evaluated first in healthy volunteers. Subsequently a proof of concept study in patients with viral pneumonia will be conducted at the Medical University of Vienna. In parallel, existing data on the effectiveness of Carragelose®serve as basis for in-vitro tests that will be carried out together with the Medical University of Vienna in order to establish safety and effectiveness.



Broad effectiveness of Carragelose®

Products containing Carragelose®as an active ingredient have been on the market for several years as nasal sprays, throat sprays and lozenges as therapeutic agents against respiratory infections. Based on the sole physical mode of action, the products are certified as medical devices and are characterized by their very broad effectiveness against different respiratory viruses.


Carragelose®was first successfully tested in vitro against human rhinoviruses, human coronaviruses (OC43 and 229E), human influenza viruses A (nH1N1 and H3N2), non-human pathogenic influenza A viruses (H7N7 and H5N1), respiratory syncytial virus and human parainfluenza virus.


This broad effectiveness was later clinically demonstrated in four studies. Patients with early symptoms of cold&flu-like infections were treated with a Carragelose®nasal spray. The results showed that patients treated with Carragelose®nasal sprays had significantly shortened period of symptoms when compared to placebo patients. The viral load and the recurrence of symptoms were also significantly reduced. A subgroup analysis with those patients infected with either human rhinoviruses, human coronaviruses or human influenza A viruses showed that results in all three groups were similar to those in the group of all virus-positive patients. The greatest reduction in symptoms was achieved in coronavirus-infected patients who, when treated with a nasal spray containing Carragelose®, were symptom-free more than three days earlier than the comparison group with placebo treatment.


The current project is funded by the FFG as part of the "Emergency Call to research COVID-19 in the wake of the outbreak of SARS-CoV-2". The planned project volume is above EUR 4 million, the maximum funding share is 45%.


About Marinomed Biotech AG

Marinomed Biotech AG is a biopharmaceutical company with headquarters in Vienna (Austria) and listed on the Prime Market of the Vienna Stock Exchange. The company focuses on the development of innovative products based on patent-protected technology platforms in the field of respiratory and ophthalmological diseases. The Marinosolv®technology platform increases the efficacy of hardly soluble compounds for the treatment of sensitive tissues such as the eyes and nose. The Carragelose®platform comprises innovative patent-protected products targeting viral infections of the respiratory tract. Carragelose®is used in nasal sprays, throat sprays and lozenges, which are sold via international partners in over 40 countries worldwide. Further information is available at:


For further enquiries please contact:

Dr. Eva Prieschl-Grassauer

Chief Scientific Officer, Marinomed

Veterinärplatz 1, 1210 Vienna, Austria
T +43 (0)1 250 77 4460

Roland Mayrl

Managing Partner, Metrum Communications

Bauernmarkt 10/19, 1010 Vienna, Austria

T +43 (0) 1 504 69 87 331




This press release contains forward-looking statements, which are based on current views, expectations and projections of the management of Marinomed Biotech AG about future events. These forward-looking statements are subject to risks, uncertainties and assumptions that could cause actual results, performance or events to differ materially from those described in, or expressed or implied by, such statements. The current views, expectations and projections of the management of Marinomed Biotech AG may be identified by the context of such statements or words such as “anticipate,” “believe”, “estimate”, “expect”, “intend”, “plan”, “project” and “target”. Forward-looking statements are only valid as of the date they are made and Marinomed Biotech AG does not assume any obligation to update, review or revise any forward-looking statements contained in this press release whether as a result of new information, future developments or otherwise.

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Last Updated: 28-Apr-2020