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Koura announces major investment into new ‘greener’ medical propellant production facility in United Kingdom

This investment signals a key milestone of bringing the new ‘greener’ medical propellant to the pMDI market.


Thornton, UK. June 30, 2020 – Koura announced today a multimillion-pound sterling investment into a new cGMP Zephex® 152a medical propellant production facility at their Runcorn, UK location.

This investment is part of a program to bring Zephex® 152a from the laboratory to the patient and will provide a scaling-up in production capacity to meet the increasing demands of customers for high purity, medical grade 152a.

The facility is expected to be commissioned and operational by late 2021 and will lead to the creation of a number of highly skilled job opportunities within the local area.

Global Warming Potential (GWP) is a measure of the atmospheric warming potential of a propellant upon release into the atmosphere. Pressurized metered-dose-inhalers (pMDIs) using Zephex® 152a will bring about a greater than 90 percent reduction in GWP compared to current pMDI propellants1.

The use of Zephex® 152a will bring pMDIs to the forefront of ‘green’ portable inhalation medicine delivery technologies.



Koura is a global leader in the development, manufacture and supply of fluorinated products that play a fundamental role in enhancing everyday lives. Koura is part of the Orbia community of businesses working together to advance life around the world. Koura's products are used in a range of applications including the construction of towns and cities, keeping homes cool, food fresh and treating patients with respiratory conditions through providing medical propellants used in 80% of the world's pressurized metered-dose inhalers (pMDIs). Headquartered in Boston, Koura has commercial activities worldwide, with operations in the UK, Mexico, United States, Canada, India and Japan.


Orbia is a community of businesses united by a shared purpose: to advance life around the world. The businesses that make up Orbia have a collective focus on ensuring food security, reducing water scarcity, reinventing the future of cities and homes, connecting communities to data infrastructure and expanding access to health and wellness with advanced materials. Orbia operates in the Precision Agriculture, Building and Infrastructure, Fluor, Polymer Solutions and Data Communications sectors. The company has commercial activities in more than 100 countries and operations in 44, with global headquarters in Mexico City, Boston, Amsterdam and Tel Aviv. For more information, please visit

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Last Updated: 15-Jul-2020