Alkaline Proteases Market Growth Strategies for 2020, Industry Share Valuation, Worldwide Demand, Key Advancements, Upcoming Trend and Global Forecast to 2026
Impact Analysis of Covid-19
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Alkaline proteases, also known as basic proteases, are a group of enzymes that find application as additives in detergents. Alkaline proteases are obtained from various microbial sources such as fungi, bacteria, and certain yeasts and can resist extreme alkaline environments produced by a wide range of alkalophilic microorganisms. There are two types of alkaline proteases: serine protease and metalloprotease. Moreover, based on the position of the peptide bond cleavage, alkaline proteases are also classified as endo-peptidases and exo-peptidases. Enzymes are used as alternatives to chemicals to enhance the efficiency of several industrial processes. Alkaline proteases are active in a neutral to alkaline pH range and have an optimum pH of around 10 and an isoelectric point of around pH 9.
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Global Alkaline Proteases Market: Drivers
Alkaline proteases have high degree of cross-linking to hydrogen bonds, disulphide bonds, and hydrophobic interactions, which offers them high stability in association with chelating agents and perbonates and are resistant to proteolytic hydrolysis. Such benefits are expected to boost growth of the global alkaline proteases market over the forecast period. Moreover, increasing R&D in protein engineering and industrial enzymes is also expected to propel growth of the market.
Although high production cost of extracellular enzymes is restricting their use in remediation, R&D in the field of immobilized enzymes is expected to offer lucrative growth opportunities in the global alkaline proteases market. Moreover, increasing development in microbiology and biotechnology is also creating conducive environment for market growth. R&D for enhanced stability to pH, temperature, organic solvents, reuse, and recovery of enzymes using enzyme immobilization techniques such as whole cell and cell free immobilization techniques and characterization of enzymes, isolation and identification of promising strains, and optimization of products are some of the factors boosting growth of the market.
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Global Alkaline Proteases Market Taxonomy
The global alkaline protease market outlook can be segmented on the basis of:
Global Alkaline Proteases Market: Segment Analysis
On the basis of application, the global alkaline proteases market is segmented into detergents, pharmaceuticals, meat tenderizers, protein hydrolyzates, food products, and waste processing.
Alkaline proteases are used in bioprocessing of used X-ray or photographic films for silver recovery. More effective cleaning properties, safer dirt removal conditions, and higher performance efficiency at lower washing temperature has increased the use of alkaline proteases in detergents compared to conventional synthetic proteases. Proteases derived from Aspergillus oryzae are used as a diagnostic aid in certain lytic enzyme deficiency syndrome. Alkaline proteases with keratinolytic activity can also be used in feather degradation and feather meal production for glues, fertilizers, biodegradable foils, and films.
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Bacteria and fungi are a major source of alkaline proteases and Bacillus species is used in bioremediation mixes, or as probiotic agent in aquaculture. Immobilized alkaline protease obtained from Bacillus subtilis can find application in ointment compositions, non-woven tissues, gauze, new bandage materials, and for management of waste feathers from poultry slaughterhouse. Bacillus licheniformis and Bacillus coagulans are used in large scale production of alkaline proteases. Other sources of alkaline proteases include Aspergillus species, Issatchenkia orientalis, Yarrowia lipolytica, Aureobasidium pullulans, and Cryptococcus aureus. Alkaline proteases derived from fungi offer benefits of separation due to easy removal of the mycelia from the final product using simple filtration. Moreover, production of fungus is cheap.
Global Alkaline Proteases Market: Regional Analysis
North America is expected to hold dominant position in the global alkaline proteases market, followed by Europe, over the forecast period. This is attributed to high presence of end-use industries and increasing investment in industrial infrastructure development in the region. China and India are major growth engines in Asia Pacific market.
Global Alkaline Proteases Market: Competitive Landscape
Major players in the market are focused on product development to expand their product portfolio. For instance, in July 2018, Royal DSM introduced PreventASe XR, an enzymatic solution that prevents the formation of acrylamide in high-pH applications to extend use of enzymatic acrylamide-reduction solution to more snacks and baked goods.
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Major market players are also focused on expanding their geographical presence to enhance their market share. For instance, in June 2019, Novozymes started a new office in Kenya with the objective to expand its presence in East Africa. Moreover, the company was named the most innovative company in Denmark by European Patents Office in March 2019.
Major players operating in the global alkaline proteases market include, Advanced Enzymes, Novozymes, Noor Enzymes, Royal DSM, Ab Enzymes, Acumedia Manufacturers, Inc., Solvay Enzymes, Specialty Enzymes & Biotechnologies Co., and Sigma Aldrich Corporation.
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