Biochips Market to Touch a Valuation of US$ 26,715.0 Million by 2025 | Coherent Market Insights

Biochips Market – Insights

Biochips are a class of technology that can perform simultaneous biochemical reactions. They can be classified as DNA chips, protein chips, lab-on-a-chips, and tissue and cell arrays on the basis of functionality. DNA chips, biochips or DNA microarrays contain a microscope slide made of materials such as glass, silicon chips, and nylon membrane, which is printed with thousands of minute spots. These spots contain a known DNA sequence or gene in an orderly sequence. DNA microarray relies on nucleic acid hybridization principle. cDNA microarrays, Oligo DNA microarrays, BAC microarrays, and SNP microarrays are the types of DNA microarrays. Platforms in protein microarrays or protein chips are made of glass or silicon containing spots of proteins arranged at defined locations, which interact with probe molecule in high-throughput manner. Protein arrays find application in protein function, expression profiling, drug discovery, and biomarker discovery. HuProt Proteome Microarray, ZikaProt (ZIKV/DENV) Proteome Microarray, Mycobacterium Tuberculosis (MTB) proteome microarray, GeneChip miRNA Array, Axiom genotyping array, and BovineSNP50 v3 DNA analysis beadchip are some of the commercially available biochips.

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Increasing technological development in biochips platforms is expected to boost growth of the biochips market

Microarray and microfluidics technology aid to decrease time and costs required for conventional laboratory-based approach of research. Advantages of microfluidics include, reduced assay costs due to requirement of less amount of sample in nano-liter or pico liter volume, reduced labor cost, and increased sensitivity, accuracy, and throughput as compared to conventional laboratory procedures. The products based on DNA microarrays, protein chips, lab-on-a-chip, and organ-on-a-chip technologies have significantly decreased current issues associated with time and costs in their respective applicable fields. Major institutes are focused on R&D in microarray and microfluidic technologies for various applications, which is expected to propel growth of the market over the forecast period. For instance, in 2017, Griffith Institute for Drug Discovery (GRIDD) started the development o-f microfluidic platform to further reduce time and costs required for research.

The global biochips market was valued at US$ 7,026.4 million in 2016 and is expected to witness a robust CAGR of 16.2% over the forecast period (2017 – 2025).

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Figure 1. Global Biochips Market Share (%), By Product Type, 2017 & 2025

Increasing R&D in the biochips technology is expected to contribute to growth of the market

The market is expected to witness significant growth, owing to extensive R&D that facilitates high adoption of biochips technology. For instance, scientists at Harvard University have demonstrated the use of paper and threads as an effective option for cheap microfluidic devices. Integration of electrodes and electrical textile valves into these devices could make it further useful. An article published in Royal Society of Chemistry in 2017 consists of a method of pre-concentration (P-CLIP), which could help in overcoming challenges associated with detecting low concentrations of target analytes in small sample volumes, especially for diagnosis of infectious diseases. Furthermore, the Laboratory of Integrated Bio Medical/Nanotechnology & Applications at the University of Illinois has developed a microfluidic POC sepsis chip, which is capable of quantifying total white blood cell counts and CD64 expression levels on neutrophils in around 30 minutes, using just 10 microliters of a blood sample. According to the National Center for Biotechnology Information (NCBI), a microfluidic biochip can isolate single circulating tumor cells and help in delivery of personalized medicine in non-small cell lung cancer patients.

However, complex manufacturing processes in biochip technology and high expenditure associated with R&D of biochips is expected to hinder the market growth. In biochips, processes that require a complete laboratory are miniaturized on a silicon or glass chip. However, the cost of the technology is high for end users such as research laboratories with limited funding.

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Major players operating in the biochips market include, Randox Laboratories, Fluidigm Corporation, Abbott Laboratories, Agilent Technologies, Inc., ThermoFisher Scientific, Inc., Bio-Rad Laboratories, Inc., Illumina, Inc., PerkinElmer, Inc., CDI Laboratories, Inc., InDevR, Inc., and Illumina, Inc.

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