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03-Mar-2021

Arrival of Advanced Technologies Push Tissue Engineered Skin Substitute Market, Says FMI

Wound management space has been expanding with soaring incidents of chronic diseases, and skin deformities across the world. Tissue engineered skin substitutes have emerged as a result of advancements in tissue engineering and advent of innovative manufacturing techniques with biomaterials and cell structure systems.

Established players are leveraging new-age fabrication methods, such as 3D bioprinting and biotextile, for producing advanced tissue engineered skin substitutes. Stakeholders eye North America and Europe for lucrative prospects owing to increasing cases of diabetic and venous ulcers. The global tissue engineered skin substitute market is projected for a robust 9% CAGR during (2019 – 2029).

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Rising Adoption in Treating Chronic Wounds

Tissue engineered skin substitutes have been garnering significant application in treating chronic wounds, which contribute ~70% of market share. Type I and end-stage diabetes are leading causes of mortality in developed countries. Studies suggest that incidents of diabetic ulcers are increasing at a rate of 9% a year. About 10 million individuals complain of venous ulcers, and diabetic ulcers globally, particularly in developing regions. These facts indicate the need for tissue engineered skin substitutes in treating various chronic wounds.

However, usage of tissue engineered skin substitutes in addressing chronic wounds is expected to witness slight decline in upcoming years. Market players are increasing investments in innovating novel designs of tissue engineered skin substitute.  

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Biological Skin Substitutes Remain In-Demand

Biological skin substitutes account for about half the market revenue, finds FMI. Tissue engineered skin substitutes derived from biomaterial matrix are portraying vital role in regeneration of functional tissues. In addition, biological skin substitutes enable formation of more natural new dermis and impart exceptional re-epithelialization features owing to presence of a basement membrane.

Biological skin substitutes, including allografts, and xenografts, are garnering prominence in wound management. While allografts offer benefits of reduced operation, and less painful initial recovery, xenografts prove to be efficient in treating partial-thickness wounds, such as scalds. Yet, the latter is expected to generate relatively lower revenue due to limited availability, and high costs of human skin tissue.

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Analysts at FMI suggest that “The market of tissue engineered skin substitutes is growing healthily on back of continuous clinical research. Onset of space-age technologies, such as 3D bioprinting, are further propelling the market. However, failure of tissue engineered skin substitutes to develop skin appendages, including hair follicles, and sebaceous glands, remains the area of concern.”

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Last Updated: 03-Mar-2021