Osteonecrosis Treatment Market – Global Industry Size, Trends, Investment Share, Treatment Technology, Key Trends, Demand, Business Growth and Forecast From (2020 to 2026)
Global Osteonecrosis Treatment Market
Osteonecrosis is a disease in which the bone cells die or collapse due to lack of blood flow in the bones. It is also known as avascular necrosis, aseptic necrosis or ischemic necrosis. Osteonecrosis is most commonly developed in hip bone (femur) or knees, while less often in shoulder, wrist, ankle, hands, and feet. It can cause mild to severe pain and may lead to micro-fracture. Osteonecrosis can be diagnosed by using X-ray, CT scan, MRI, bone scan, and functional bone tests. Osteonecrosis treatment targets symptoms and reduces pain via medication or surgery in extreme cases. According to the National Organization for Rare Disorders, osteonecrosis is one of the rare diseases, where less than 1 in 2000 are only affected by this disorder. In 2017, Bone Therapeutics reported that around 170,000 patients were suffering from osteonecrosis in Europe, the U.S., and Japan. The advancements in treatment technologies and gene therapy and stem cell-based osteonecrosis treatment are expected to propel growth of the global osteonecrosis treatment market during the forecast period.
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Global Osteonecrosis Treatment Market Taxonomy
By Drug Class:
- Non-steroidal anti-inflammatory drugs (NSAIDs)
- Other drugs
By Distribution Channels:
- Hospitals pharmacies
- Retail pharmacies
- Online pharmacies
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Global Osteonecrosis Treatment Market Outlook
Advanced Therapy Medicinal Products (ATMPs) are a class of innovative therapies that comprise gene therapy, somatic cell therapy, and tissue-engineered products, and their introduction into the market is expected to drive the global osteonecrosis treatment market development. Osteonecrosis usually affects young population and this significantly will contributes towards growth of osteonecrosis treatment market. For instance, according to the American College of Rheumatology, in 2017, around 10,000 to 20,000 people in the U.S. who suffered from osteonecrosis were between the ages of 20 and 50. Currently, the osteonecrosis non-surgical treatment (medication) is symptomatic treatment that targets the symptoms and try to cure the disease. Hence, emerging players in the field of bone disease treatment is gaining momentum by introducing gene regulation approach. The key market players like Enzo Biochem, Inc. and Bone Therapeutics are aiming gene regulation and cell-based product treatment, which is expected to augment growth of osteonecrosis treatment market. For instance, PREOB manufactured by Bone Therapeutics, a cell-based medicinal product derived from autologous bone marrow stem cells, has been approved in the U.S., and is currently in the third phase of development in Europe.
Although osteonecrosis is a rare disease, the global osteonecrosis treatment market is expected to grow tremendously, due to the burgeoning prevalence of causative agents for osteonecrosis. Side effects of various medicines taken during cancer, HIV/AIDS, osteoarthritis, osteoporosis or blood disorders or medical treatment such as chemotherapy, radiation therapy, high-dosage of steroids or organ transplants may increases the chances of having osteonecrosis. Furthermore, a few interventions such as Stanford University’s sponsored project aims at evaluation of osteonecrosis before and after decompression surgery with ferumoxytol-enhanced MRI, which improve detection and allow to track transplanted bone marrow cells. This intervention is in phase IV clinical trial and is expected to complete the project over the forecast period, which in turn, would propel the growth of the global osteonecrosis treatment market.
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North America is expected to hold a dominant position in the global osteonecrosis treatment market over the forecast period, due to increasing prevalence pool of osteonecrosis, and FDA approvals for new treatment options in the region. According to the 2015 NCBI report, it is estimated that around 20,000 to 30,000 new patients are diagnosed with osteonecrosis in the U.S. annually. Furthermore, the Asia Pacific market is expected to grow at a comparatively faster rate in the global osteonecrosis treatment market over the forecast period, owing to the increasing developmental activities carried out by various key players in this region. For instance, Bone Therapeutics and Asahi Kasei Corporation signed a license agreement in 2017 for the development and commercialization of PREOB in Japan.
Global Osteonecrosis Treatment Market – Key Competitors
The major players involved in the global osteonecrosis treatment market include Bone Therapeutics, Enzo Biochem Inc., K-Stemcell Co. Ltd. Hospitals, and numerous leading universities and institutes.
Table of Content
Global Osteonecrosis Treatment Market Research Report
Section 1: Global Osteonecrosis Treatment Industry Overview
Section 2: Global Economic Impact on Osteonecrosis Treatment Industry
Section 3: Global Market Competition by Industry Producers
Section 4: Global Productions, Revenue (Value), according to Regions
Section 5: Global Supplies (Production), Consumption, Export, Import, geographically
Section 6: Global Productions, Revenue (Value), Price Trend, Product Type
Section 7: Global Market Analysis, on the basis of Application
Section 8: Osteonecrosis Treatment Market Pricing Analysis
Section 9: Market Chain, Sourcing Strategy and Downstream Buyers
Section 10: Strategies and key policies by Distributors/Suppliers/Traders
Section 11: Key Marketing Strategy Analysis, by Market Vendors
Section 12: Market Effect Factors Analysis
Section 13: Global Osteonecrosis Treatment Market Forecast
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