Metastatic Osteosarcoma Treatment Market 2026 Recent Trends, Growth Opportunities, Forecast by Application and Types with Worldwide Top Key Players
SEATTLE, March 25, 2021, (PHARMIWEB) — Global Metastatic Osteosarcoma Treatment Market — Insights
Osteosarcoma, also known as bone cancer, is characterized by abnormal growth of bone tissues. The condition is progressive and can spread from source to other organs such as lungs and brain, a condition referred as metastatic osteosarcoma. There are various symptoms of metastatic osteosarcoma based on the location of tumor such as bone pain, bone fracture, swelling, redness, limping, and limited joint movement. Progression of the condition in lungs can lead to symptoms such as chest pain, shortness of breath, cough with blood, chronic coughing or wheezing.
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CT-scan, MRI, X-ray, PET scan, biopsy, and bone scan are used to diagnose metastatic osteosarcoma. Surgery, radiation, chemotherapy, biological therapy or a combination of these treatments is effective against metastatic osteosarcoma. The preference for combinational treatment also known as multi-modality treatment is more as it enhances the outcome or increase survival rate.
Increasing R&D in metastatic osteosarcoma therapies to augment growth of the market
Key players in the market are focused on developing new therapies for the treatment of metastatic osteosarcoma. This is expected to boost growth of the global metastatic osteosarcoma treatment market. For instance, in 2017, Merck & Co., Inc. assessed the impact of Pembrolizumab (MK-3475) in patients with relapsed or metastatic osteosarcoma and reported that these patient are not eligible for curative surgery. Currently, the study is in phase II clinical trial and is expected to be completed in 2023. Moreover, Novartis entered into phase II clinical trials for pazopanib for the treatment of metastatic osteosarcoma as of March 2018.
Increasing focus on the development of new therapies for the treatment of metastatic osteosarcoma is also expected to propel growth of the market. For instance, immunotherapy-based drugs and targeted drug therapy have low side-effects and can be effective in the treatment of metastatic osteosarcoma. In immune therapy, immune checkpoint inhibitors can identify and target cancer cells for effective results against metastatic osteosarcoma. Moreover, engineered monoclonal antibodies can target mTOR protein in order to restrict new blood vessel formation or hamper growth of tumor cells. For instance, Aadi, LLC studies Nivolumab (Opdivo) in combination with ABI-009 (Nab-rapamycin, the mTOR inhibitor) for potential anti-tumor activity for Ewing Sarcoma. The study is in phase II clinical trial and is expected to complete by 2020.
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Around 35% of pediatric patients that suffer from osteosarcoma fail first-line of therapy, which can lead to recurrence of metastatic osteosarcoma in lungs. Key players in the market are focused on developing new therapies for the treatment of metastatic osteosarcoma in lungs. For instance, in 2013, Elesion Pharmaceuticals LLC, a pharmaceutical company developing life-saving therapeutics for rare cancers, entered into phase II clinical trials for Inhaled Lipid-complexed Cisplatin (ILC), a novel sustained release formulation of cisplatin in a nanoscale lipid based complex, for pediatric patients with osteosarcoma metastases for lungs. Such scenario is expected to boost growth of the market over the forecast period.
Moreover, key players in the market are focused on adopting product approval and launch strategies in order to expand their product portfolio. This is expected to propel growth of the global metastatic osteosarcoma treatment market. For instance, in, lipid-complexed cisplatin received orphan drug designation by European Medicines Agency for the treatment of osteosarcoma. In 2015, company entered in partnership with Intelgen Limited, a Hong Kong-based biopharmaceutical company, for specialized novel anti-cancer drug development and commercializing ILC in Chinese market. Moreover, in 2014, Oncolytics Biotech examined safety and efficacy of Reolysin for the treatment of bone and soft tissue sarcoma metastatic for lungs.
Availability of alternative therapies to hinder the market growth
Availability of alternative therapies such as new forms of radiation therapy (intensity-modulated radiation therapy, stereotactic radiosurgery or conformal proton beam therapy) is expected to hinder growth of the market. Regulatory bodies worldwide have also imposed stringent approval policies for drug therapies, which is also expected to restrict growth of the market.
North America is expected to account for the largest market share
The market in North America is expected to account for the largest market share over the forecast period. This is attributed to increasing R&D of new therapies and high prevalence of metastatic osteosarcoma. For instance, in 2016, according to American Society of Clinical Oncology (ASCO), 1,000 people are diagnosed with osteosarcoma, annually. Increasing prevalence of metastatic osteosarcoma is expected to boost growth of the market in Asia Pacific.
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Global Metastatic Osteosarcoma Treatment Market: Competitive Landscape
Major players operating in the global metastatic osteosarcoma treatment market include, Sun Pharmaceutical Industries Ltd., Dr. Reddy’s Laboratories Ltd., Luitpold Pharmaceuticals Inc., Mylan Laboratories Limited, Actavis Inc., Alvogen Inc., Gland Pharma Limited, and Sagent Pharmaceuticals Inc.
Metastatic Osteosarcoma Treatment Market – Taxonomy
By Drug Type
By Distribution Channel
- Hospital Pharmacies
- Retail Pharmacies
- Online Pharmacies
- North America
- Latin America
- Asia Pacific
- Middle East
Table of Content
Global Metastatic Osteosarcoma Treatment Market Research Report
Section 1: Global Metastatic Osteosarcoma Treatment Industry Overview
Section 2: Global Economic Impact on Metastatic Osteosarcoma Treatment Industry
Section 3: Global Market Competition by Industry Producers
Section 4: Global Productions, Revenue (Value), according to Regions
Section 5: Global Supplies (Production), Consumption, Export, Import, geographically
Section 6: Global Productions, Revenue (Value), Price Trend, Product Type
Section 7: Global Market Analysis, on the basis of Application
Section 8: Metastatic Osteosarcoma Treatment Market Pricing Analysis
Section 9: Market Chain, Sourcing Strategy, and Downstream Buyers
Section 10: Strategies and key policies by Distributors/Suppliers/Traders
Section 11: Key Marketing Strategy Analysis, by Market Vendors
Section 12: Market Effect Factors Analysis
Section 13: Global Metastatic Osteosarcoma Treatment Market Forecast
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