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31-Mar-2021

Global Cardiac Resynchronization Therapy market size to reach US$ 8.6 Bn by 2026 at a CAGR of 5.3%

Noida,Uttar Pradesh, India,Mar 31 2021 (WiredRelease) Report Ocean Pvt Ltd–:Increasing incidence of target diseases, rising geriatric population, rising investment in the cardiology field, and improving R&D facilities in emerging markets are factors that drive market growth across the globe. To raise awareness and promote cardiac resynchronization therapy market developments, guidelines have been devised by agencies such as the European Heart Rhythm Association and the European Society of Cardiology. These guidelines have been detailed into three subsets based on the type of patient to offer accurate decision-making. Following these promising developments, the Global Cardiac Resynchronization Therapy Market is estimated to see healthy growth, pegged at a CAGR of around 5.3% throughout the forecast period 2020-2025.

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Cardiac resynchronization therapy (CRT) is an established therapy for patients dealing with cardiomyopathy, heart failure, and left bundle branch block. His bundle pacing (HBP) can improve clinical outcomes by narrowing QRS duration; however, it may not always be optimal. Several evidence for CRT benefits rises from trials that joined New York Heart Association (NYHA) functional classes III and IV patients. Though the subsequent trials presented a response to CRT in less-sick patient cohorts, including NYHA functional classes I and II patients, the evidence is vital for patients with symptomatic HF (NYHA classes II-IV). However, there are certain specific patient scenarios in which earlier execution of CRT may be considered.

Supposedly, the electrical dyssynchrony seen with QRS complex duration and morphology changes fortifies mechanical dyssynchrony, leading to futile LV function. CRT aims to rectify this problem by restoring interventricular and intraventricular synchrony. Therefore, it was a natural side effect, including evaluating the utility of CRT in patients with mechanical dyssynchrony in the non-existence of electrical dyssynchrony. However, a few trials did not show any benefit with the usage of CRT in patients with mechanical dyssynchrony upon evaluation with cardiac imaging. Furthermore, one of these trials showed a potential for damage with CRT use in patients with a QRS complex duration of less than 130 ms and echocardiographic evidence of mechanical dyssynchrony.

The efficiency of imaging markers, such as echocardiographic parameters, to evaluate dyssynchrony was initiated after the publication of the Predictors of Response to CRT (PROSPECT) large international observational study. The trial aimed to assess 12 predefined echocardiographic factors regarding their capability to predict clinical and echocardiographic reactions to CRT. Ultimately, these parameters’ ability to predict benefit with CRT remained modest, with significant interobserver variability observed in the analysis of dyssynchrony parameters regardless of specific training.

Segmentation Overview of the Global Cardiac Resynchronization Therapy Market

The cardiac resynchronization therapy market is segmented based on the product type and end user. These major market segments are further categorized into various sub-segments to study the market in detail.

By Product Type Outlook (Cardiac Resynchronization Therapy Pacemakers, Cardiac Resynchronization Therapy Defibrillators)

By End User Outlook (Hospitals & Cardiac Centers, Ambulatory Surgery Centers)

Key Players Insights

Medtronic PLC, Abbott Laboratories, Boston Scientific Corporation, MicroPort Scientific Corporation, BIOTRONIK, and Medico S.p.A., among others, are some significant players included in the research study of the global cardiac resynchronization therapy market.

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Last Updated: 31-Mar-2021