Tamoxifen Market Growth Insight: Global Industry Analysis by Size, Share, Comprehensive Analysis, Future Trends and Competitive Landscape to Forecast by 2026
SEATTLE, April 01, 2021, (PHARMIWEB) — Global Tamoxifen Market
Tamoxifen is a type of selective estrogen receptor modulator (SERM) indicated for the treatment of women at a high risk of breast cancer. Since its approval in 1998, tamoxifen has been used to treat millions of patients diagnosed with hormone receptor-positive, as well as early-stage breast cancer, usually post-surgery to reduce the chances of recurrence. It is one of the first choices for the treatment of premenopausal women. For the record, tamoxifen is the generic name for Nolvadex. It has an off-label usage for the treatment of infertility, gynecomastia, retroperitoneal fibrosis, and idiopathic sclerosing mesenteritis.
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The main pharmacological function of Tamoxifen is to block the growth-promoting effects of estrogens on breast cancer. In bone cells, selective estrogen modulators interact with receptors the way estrogen does and strengthens bones. Tamoxifen is available in various forms, such as powder, capsules, oral solutions, and tablets.
Global Tamoxifen Market Dynamics
Since tamoxifen is a generic molecule, growth of the global tamoxifen market has declined with increased competition. However, the emergence of combination therapies and additional therapeutic indications for tamoxifen is expected to fuel the global market growth. For instance, 2018 Novartis received breakthrough therapy designation for Kisqali by FDA in Phase 3. Designation was based on the successful phase 3 MONALEESA-7 trials, which demonstrated significant prolonged-free survival (PFS) of Kisqali + tamoxifen (or an aromatase inhibitor).
Moreover, increased investments from government and non-government organizations intended to discover the additional therapeutic applications of tamoxifen, are projected to propel the global market growth. For instance, in 2017, Duchenne UK, E-Rare, Duchenne Parent Project, and Monaco Association jointly contributed up to US$ 766,338 for a clinical trial that was aimed at studying the effects of tamoxifen on muscular dystrophy.
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However, in 2017, a survey conducted by the European Cancer Congress discovered that the cost of tamoxifen, despite being generic, increased around ten times over 2011-2016. The research found that the cost of the drug was 20 times the price in India. Such disparity in prices, with no adequate reimbursement deters acceptance for the drug. Furthermore, adverse effects of tamoxifen therapy such as anxiety, vaginal discharge, and painful urination, is expected to hamper the global tamoxifen market growth. Furthermore, rising prevalence of breast cancer among women, in both developed and evolving economies, is a major aspect fueling the growth of the global tamoxifen market.
Global Tamoxifen Market – Regional Insights
The North America tamoxifen market holds a highly dominant position in the global market, owing to high prices of the drug used in treating breast cancer. According to GoodRx Inc.’s 2018 pricing detail, 30 tablets of tamoxifen 20mg cost around US$ 65.71 on an average. In addition, rising prevalence of breast cancer has propelled the tamoxifen market growth in this region.
Asia Pacific is expected to witness considerable growth in the global tamoxifen market over the forecast period, owing to the increasing vulnerability among people to various chronic diseases, and growing number of healthcare initiatives. According to an article published in the Lancet Oncology 2014, the incidence rate of breast cancer in the region is expected to rise from less than 60 cases per 100,000 women, aged 55 years to 69 years, to over 100 cases per 100,000 women by 2021.
Global Tamoxifen Market – Competitive Scenario
The key players operating in the global tamoxifen market include Teva Pharmaceutical Industries Ltd, AstraZeneca Plc, Aegis pharmaceuticals, Watson laboratories, Inc., Allergan Plc, Mylan N.V., and Apotex Inc.
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These players are presently focusing on the adoption of various strategies, such as acquisitions and mergers, to provide advanced research products to sustain their presence in the global market. For instance, in 2018, Dare Bioscience Inc. announced a merger agreement with Pear Tree Pharmaceuticals to procure the rights to develop PT-101, as a potential treatment for vaginal and vulvar atrophy for patients suffering from hormone-receptive positive breast cancer. PT-101, for the record, is a proprietary vaginal formulation being developed by Pear Tree Pharmaceuticals.
On the basis of dosage form:
- Oral Solution
Based on indication:
- Breast Cancer
- North America
- Latin America
- Asia Pacific
- Middle East
Table of Content
Global Tamoxifen Market Research Report
Section 1: Global Tamoxifen Industry Overview
Section 2: Global Economic Impact on Tamoxifen Industry
Section 3: Global Market Competition by Industry Producers
Section 4: Global Productions, Revenue (Value), according to Regions
Section 5: Global Supplies (Production), Consumption, Export, Import, geographically
Section 6: Global Productions, Revenue (Value), Price Trend, Product Type
Section 7: Global Market Analysis, on the basis of Application
Section 8: Tamoxifen Market Pricing Analysis
Section 9: Market Chain, Sourcing Strategy, and Downstream Buyers
Section 10: Strategies and key policies by Distributors/Suppliers/Traders
Section 11: Key Marketing Strategy Analysis, by Market Vendors
Section 12: Market Effect Factors Analysis
Section 13: Global Tamoxifen Market Forecast
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