ReiThera Completes Enrolment of Subjects in the Phase 2 Part of the Phase 2/3 Clinical Trial of its GRAd-COV2 Vaccine Candidate against COVID-19

ReiThera Completes Enrolment of Subjects in the Phase 2 Part of the Phase 2/3 Clinical Trial of its GRAd-COV2 Vaccine Candidate against COVID-19

ROME, Italy, April 26^th, 2021 - ReiThera Srl, a biotech company dedicated to the technology development, GMP manufacturing and clinical translation of genetic vaccines and medicinal products for advanced therapies, announces that it has completed the enrolment of 900 healthy volunteers in the Phase 2 part of its Phase 2/3 clinical trial of GRAd-COV2, its vaccine candidate against COVID-19 (SARS-CoV-2). The study, named COVITAR (GRAd-COV2 ITAlian Vaccine Reithera), is being conducted at 26 clinical sites in Italy.

ReiThera’s Chief Executive Officer, Antonella Folgori, said: “We have seen a strong participation in the Phase 2 study, thanks to the commitment of the clinical centers and all the investigators involved in the study. We would also like to thank Invitalia and INMI Spallanzani for their continued support and in particular ReiThera’s teams for their dedication and hard work over the past few months. We are committed to continuing the development of the GRAd-COV2 vaccine and if all proceeds as planned, we expect to conduct the Phase 3 part of the trial over the summer.”

Stefano Colloca, Chief Technology Officer of ReiThera, added: “ReiThera is in an excellent position to address the COVID-19 challenge. In 2020, we invested in the expansion of our manufacturing plant in Rome which will have the capacity to produce up to 100 million vaccine doses per year. In parallel, and as part of an effort stimulated by the Italian government, we have the know-how and production capacity available to respond positively to any requests for the production of other approved COVID-19 vaccines based on mRNA and adenoviral vectors, as part of our commitment to the global effort to protect people from the pandemic.”