Anti-Cathepsin B Market Research Report, Status and Forecast, by Players, Types and Applications
The report for the Anti-Cathepsin B Market presents a detailed insights on market shares, growth opportunities, and regional and sub-regional prospects. The report also discusses market competition landscape and a relatively detailed analysis of key players in the Anti-Cathepsin B Market. It also offers comprehensive study on historical market statistics and corresponding trends. The report argues about different aspects of the Anti-Cathepsin B Market such as global sales of the product, current market size, future growth opportunities, and lucrative propositions. Key players involved in the Anti-Cathepsin B Market are profiled and analyzed with details such as business overview, company product portfolio, geographical overview, and company’s business strategies. Each detail in the market and stat is validated via reliable source, recommended journals, and industry experts. The Anti-Cathepsin B report will facilitate the business owners to invest in lucrative propositions.
Impact of COVID-19 epidemic
The demand for anti-cathepsin B market has increased significantly due to COVID-19 pandemic. The transmission of COVID-19 has impacted the anti-cathepsin B market in a positive way as the antibodies are expected to potentially treat the COVID-19 infected individuals. On May 5, 2020, the Journal of Clinical Medicine Research revealed in a publication that the SARS-CoV-2 binds with angiotensin II receptor in various tissues of the body, particularly in the tongue, in the mouth cavity and the skin. Hence, for cell entry it requires the transmembrane serine protease 2 (TMPRSS2) and serine protease. Cathepsin L/B (CTSL/CTSB) plays a vital role in the endosomal pathway which is the second pathway. Therefore, for treatment of coronavirus, the anti-cethapsin B treatment may offer potential solutions.
The anti-cathepsin B market is expected to manifest a CAGR of 2.8% over the forecast period (2020-2027) and is approximated to worth around US$ 166.52 million in 2020.
Overview
A cysteine protease which can be mainly found in normal cells’ lysosomes is called as Cathelpsin B that is related to the plasma membrane of multiple transformed cells. It plays a vital role in turnover of cellular proteins and can be found in all animals and organisms. The family of cathepsin also include aspartic proteases, cysteine proteases, and serine proteases. The category of aspartyl protease consists of cathepsins E and D. The class of cysteine protease is composed of cathepsins S, H, B, O, K, and L. Presently, in the market there are no approved cathepsin inhibitors, although the research and development of novel cathepsin inhibitors in underway for treatment of several conditions such as Ebola infection, cancer, traumatic brain injury, and others.
For diagnostic purposes, this anti-cathepsin B is used in screening kits. Cathepsin B’s antibodies are used to recognize an epitope of mature cathepsin B’s heavy chain which results in detection of pro cathepsin B as well as the mature one. The antibodies of anti-cathepsin B find their applications in western bottling, flow cytometry, ELISA and in other screening purposes. It is also used to screen diseases like emphysema, rheumatoid arthritis, demyelination, and neoplastic infiltration.
Drivers
Rising incidences of disorders treated with anti-cathepsin B and the research and development activities are expected to propel growth of the global anti-cathepsin B market.
Anti-cathepsin B is poised to be fruitful in treatment of diseases such as fertility problems, cancer, Ebola infection, traumatic brain injury, and others. Hence, the rising incidences of such conditions is expected to exhibit growth of the global anti-cathepsin B market during the forecast period. As per the GLOBOCAN 2018, the numbers of global cancer are approximated to have reached 18.1 million newer cases with 9.6 million deaths. The same source revealed that 1 in 11 women and 1 in 8 men die due to this disease.
Moreover, due to rising research and development activities, the anti-cathepsin B market is expected to experience a robust growth in the near future. In September 2015, a report published by Frontiers Neurology Journal revealed a supporting evidence of cathepsin B as a potentially vital drug for treating the traumatic brain injury (TBI). In TBI models of animals and also in trauma patients, the expression of cathepsin B has significantly up-regulated.
To improve the deficits in TBI and its associated injuries such as edema, infection, cerebral bleeding, ischemia, Alzheimer’s disease, Huntington’s disease, rheumatoid arthritis, cerebral aneurysm, epilepsy, and multiple sclerosis, the chemical inhibitors of cathepsin B are found to be effective. Among cathepsin B inhibitors, the E64d inhibitor is unique and the only compound which has shown efficacy in a TBI model with prior safe use in humans, and acts as an effective tool compound for clinical compound development and for pre-clinical testing.
Market Taxonomy
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According to the Technique: Immunohistochemistry, Immunofluorescence, Western Blotting, ELISA, Flow Cytometry, Others.
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According to the type of product: Primary Antibodies, Proteins and Peptides, Lysates.
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According to the Application: Cancer, Traumatic Brain Injury, Ebola Infection, Fertility Treatment, Others.
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According to the End User: Pharmaceutical Companies, Academic and Research Institutes.
Regional Analysis
Due to high incidences of conditions such as traumatic brain injury and cancer which will result in increased demand for novel treatment approaches, the North American region is expected to maintain its dominating position in the global anti-cathepsin B market. In 2018, as per the National Cancer Institute, about 609,640 people died from cancer in the U.S. and around 1,735,350 newer cases of cancer were diagnosed in the country.
Moreover, the major companies offering a wide range of anti-cathepsin B products is expected to boost growth of the global anti-cathepsin B market during the forecast period. For instance, a German pharmaceutical, life-science and chemical company, Merck KGaA, provides several anti-cathepsin products under the brand of Calbiochem. The biological activity of Cathepsin B is controlled by the cathepsin B inhibitor II, which is mainly used for protease inhibitors techniques. The company also provides diagnostic products such as Cathepsin B inhibitor screening kit, a simple array used for inhibitor screening of cathepsin B (CTSB).
Major Key Players Include In Anti-Cathepsin B Market: Merck KGaA, Bio-Techne, BioVision Inc., Santa Cruz Biotechnology, Inc., MedChemExpress, BioCat GmbH, ApexBio Technology, Cayman Chemical, Selleck Chemicals, BOC Sciences, AG Scientific, Virobay Inc. and Abcam Plc
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Main points in Anti-Cathepsin B Market Report Table of Content
Chapter 1 Industry Overview
1.1 Definition
1.2 Assumptions
1.3 Research Scope
1.4 Market Analysis by Regions
1.5 Anti-Cathepsin B Market Size Analysis from 2021 to 2027
11.6 COVID-19 Outbreak: Anti-Cathepsin B Industry Impact
Chapter 2 Global Anti-Cathepsin B Competition by Types, Applications, and Top Regions and Countries
2.1 Global Anti-Cathepsin B (Volume and Value) by Type
2.3 Global Anti-Cathepsin B (Volume and Value) by Regions
Chapter 3 Production Market Analysis
3.1 Global Production Market Analysis
3.2 Regional Production Market Analysis
Chapter 4 Global Anti-Cathepsin B Sales, Consumption, Export, Import by Regions (2016-2021)
Chapter 5 North America Anti-Cathepsin B Market Analysis
Chapter 6 East Asia Anti-Cathepsin B Market Analysis
Chapter 7 Europe Anti-Cathepsin B Market Analysis
Chapter 8 South Asia Anti-Cathepsin B Market Analysis
Chapter 9 Southeast Asia Anti-Cathepsin B Market Analysis
Chapter 10 Middle East Anti-Cathepsin B Market Analysis
Chapter 11 Africa Anti-Cathepsin B Market Analysis
Chapter 12 Oceania Anti-Cathepsin B Market Analysis
Chapter 13 South America Anti-Cathepsin B Market Analysis
Chapter 14 Company Profiles and Key Figures in Anti-Cathepsin B Business
Chapter 15 Global Anti-Cathepsin B Market Forecast (2021-2027)
Chapter 16 Conclusions
Research Methodology
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