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R&D Day: Presentations to Highlight Transgene’s Competitive Positioning, Capabilities to Engineer Novel Immunotherapies for Patients with Cancer, and Update on Initial Clinical Data

Meeting to highlight Company’s innovative portfolio, supported by updated clinical data, demonstrating the potential of therapeutic vaccine and oncolytic virus candidates to improve cancer patient outcomes

Strasbourg, France, September 27, 2022, 8:00 am CEST – Transgene (Euronext Paris: TNG), a biotech company that designs and develops virus-based immunotherapeutics against cancer, will host today an R&D event for investors and research analysts in Paris. 

Hedi Ben Brahim, CEO of Transgene, commenting on the Company’s R&D Day said: “Today’s event will highlight our world leading scientific and translational expertise which has allowed us to design the next generation of virus-based immunotherapies against cancer. We will provide updated data on the previous Phase Ib/II trial of TG4001 and avelumab in HPV16-positive cancer patients and the updated clinical follow up of patients enrolled in the two Phase I trials with TG4050, which are all positive and consistent with previous findings. In addition, we will outline the progress we have made with our exciting Invir.IO™ platform, which via intravenous administration could significantly broaden the potential of oncolytic viral therapies. I would like to thank our expert speakers for participating in our R&D event which I am confident will demonstrate that Transgene remains on track to deliver a number of important value adding clinical milestones over the next 18 months.”   

The event, which features presentations by leading clinicians and scientists from around the world, as well as key members of the Transgene management team, provides insights on: 

  • TG4001, with updated data from the previous trial (Phase Ib/II) evaluating the combination of TG4001 and avelumab in HPV16-positive cancers; 
  • TG4050, with updated follow up data from the two Phase I trials in ovarian cancer and head and neck cancer; 
  • The progress of the Invir.IO™ platform, with a focus on a novel oncolytic virus vectorizing human IL-12 that has been designed to be administered intravenously.  

The R&D Day’s key speakers, which also includes key members of Transgene’s management team, are: 

  • Jean-Pierre Delord, MD, PhD, General Manager of IUCT Oncopole of Toulouse, will present: “TG4001 - a HPV16 Therapeutic vaccine in Phase II”. 
  • Christian Ottensmeier, MD, PhD, FRCP, Professor of Immuno-oncology at the University of Liverpool, The Clatterbridge Cancer Center NHS Foundation Trust, will present: “From the design of the myvac® platform to first immunological and clinical readouts, Update on the head and neck trial of TG4050”.  
  • Matthew Block, MD, PhD, Medical oncologist at the Mayo Clinic, will present: “TG4050, a personalized therapeutic vaccine in the treatment of ovarian cancer”. 
  • Adel Samson, MD, PhD, Clinical Associate Professor, CRUK Clinician Scientist and Honorary Medical Oncologist from the University of Leeds, will present: “Assessing novel routes of administration (IV or locoregional route) with TG6002”. 
  • Pedro Romero, MD, Chief Editor of the JITC and Deputy scientific managing director of the Lausanne Branch of the Ludwig Institute for Cancer Research, will present: “Opportunities in the immuno-oncology field”. 

The full agenda of the Transgene R&D Day can be accessed on Transgene’s website,, in the Investor Events and presentations section. 

The live webcast will also be accessible via the following link: R&D Day live presentation.  

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Last Updated: 27-Sep-2022