APOL1 Mediated Kidney Disease Market is expected to garner a value of USD 5753.9 million and expand at a 4.3% value CAGR by 2033

The APOL1 Mediated Kidney Disease Market is anticipated to reach a worth of USD 3779.9 million in 2023 before increasing to USD 5753.9 million by 2033, with a forecasted CAGR of 4.3%.

The current alternatives for treatment are few, and they only work to treat the signs of APOL1 Mediated Kidney Disease Market disorders, such as swelling, excess fluid retention, and hypertension. It is urgent that new and focused therapies be developed in order to lower the body’s level of the APOL1 protein. In persons with an APOL1-mediated disease, excess APOL1 leads to nephropathic symptoms and ultimately kidney failure.

The market trend for APOL1-mediated kidney illness was estimated at US$ 3.0 Billion in 2020, and Future Market Insights (FMI) projects that it will grow at a stable CAGR of over 4% over the forecast period (2020-2030).

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The top clinical-stage biopharmaceutical companies are currently concentrating on creating the next generation of tailored medicines for APOL1-treated kidney illnesses, particularly chronic kidney diseases. The intriguing but untapped market potential for APOL1-treated kidney disorders is drawing both seasoned and emerging biopharmaceuticals into the targeted therapy based strategy. Future predictions predict that this tendency will provide a competitive edge and a monopoly on the worldwide market.

For instance, in 2018, Ionis Pharmaceuticals, Inc., a clinical stage innovator company based in the United States involved in the advanced study of rare diseases, struck a $330 million licencing agreement with AstraZeneca for two pipeline antisense treatments. To treat the underlying causes of APOL1-mediated chronic kidney disorders, an investigational new antisense medication (AZD2373) is one of the approved treatments. Currently in clinical phase I, AZD2373 appears to be a viable candidate for the treatment of APOL1-mediated renal disorders in the future.

Key Takeaways from APOL1 Mediated kidney Diseases Market Study

• Chronic kidney diseases account for more than 95% of all the APOL1 mediated diseases. Increasing prevalence of hypertension associated kidney diseases will increase treatment needs over the forecast period
• North America accounts for over 3/4th of the global market. High prevalence of the disease among people with African American ancestry makes North America the leader in this market
• Pipeline drugs under development are targeted to be launched in the U.S., catapulting it as a highly lucrative pocket
• Key players are focusing on extensive research and development for targeted therapy towards APOL1
• The COVID-19 outbreak did not have any impact on the APOl1 mediated treatment market. All patients with indications like end stage kidney disorders were attended amidst COVID-19 due to the severity of kidney disease

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“Increasing research and development for discovery of underlying cause of APOL1 mediated kidney disease and its targeted therapy will propel the market growth in the future,” says FMI analyst

Who is winning? Collaboration is the key strategy amongst market players. Companies research on APOL1 therapies are strengthening their chances of successful clinical trials by collaborating with prominent pharma players. Increasing investments in drug discovery is expected to favor the growth the global market over the forecast period

• For instance, Ionis Pharma has collaborated with AstraZeneca for developing its molecule which is currently under clinical trial phase 1.

Want more insights?

Future Market Insights brings the comprehensive research report on forecasted revenue growth at global, regional, and country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2015-2030. The global APOL1 mediated kidney disease market is segmented in detail to cover every aspect of the market and present a complete market intelligence approach to the reader. The study provides compelling insights on APOL1 mediated kidney disease (Symptomatic Treatment) market on basis of indication (Chronic Kidney Disease and End Stage Kidney Disease) across North America, Europe and Middle East and Africa  and APOL1 mediated kidney disease (Pipeline Therapeutics) market on basis of indication (Chronic Kidney Disease and End Stage Kidney Disease) across North America (U.S.)

APOL1 mediated kidney diseases (Symptomatic Treatment) Market

ByIndication

• Chronic Kidney Disease
  • Focal segmental glomerulosclerosis (FSGS)
  • Human immunodeficiency virus (HIV)-associated Nephropathy
  • Hypertension-associated Kidney Disease
• End-Stage Kidney Disease

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Region

• North America (U.S.)
• Europe
• MEA

About Future Market Insights (FMI)

Future Market Insights, Inc. (ESOMAR certified, Stevie Award – recipient market research organization and a member of Greater New York Chamber of Commerce) provides in-depth insights into governing factors elevating the demand in the market. It discloses opportunities that will favor the market growth in various segments on the basis of Source, Application, Sales Channel and End Use over the next 10-years.

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