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21-Dec-2023

Bullous Keratopathy Industry Gears Up to Surpass US$ 650 Million by 2033-FMI Study

Bullous Keratopathy Industry

In 2023, the global bullous keratopathy industry size is predicted to reach a valuation of US$ 427.54 million, with a compound annual growth rate (CAGR) of 4.3% from 2023 to 2033, according to a recently released Future Market Insights research. A CAGR of 4.3% is anticipated for the assessment period of 2023 to 2033, with a closing value of US$ 650 million. The primary driver of the industry’s expansion is the growing incidence of ocular conditions such infectious keratitis, Fuchs dystrophy, and keratoconus. About 10-15% of people with keratoconus will eventually need to have a corneal implant treatment done, according to the NCBI analysis.

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Corneal blindness is the third-leading cause of blindness after glaucoma and cataract affecting 10 million people globally. The most common cause of damage to endothelium layer of the cornea is eye surgery. Any kind of trauma, glaucoma, or inflammation from eye surgery can result in bullous keratopathy. Bullous keratopathy may occur in around 1% to 2% of patients undergoing cataract surgery, a nonsignificant number when you consider that approximately 10 million patients undergo cataract surgery worldwide each year.

Collagen-based bio-engineered artificial corneas used in Bullous Keratopathy have high demand in the market owing to their advantages, such as low cost, biocompatibility, and improved safety and effectiveness. There has been an increased focus of manufacturers to develop and launch new products. Currently, two products are in clinical trials and are expected to help the artificial cornea segment and overall industry growth over the forecast period. For instance, in 2022, Corneat Vision announced that its CorNeat KPro (artificial cornea) is undergoing clinical trials. This product is expected to receive marketing approval in 2024 which will aid in the market expansion of Bullous Keratopathy.

Corneal transplantation is the decisive treatment for Bullous Keratopathy as it revives the normal structure and function of endothelial cells. It can be done in the form of penetrating keratoplasty (PK), Descemet membrane endothelial keratoplasty (DMEK) or Descemet stripping automated endothelial keratoplasty (DSAEK). A cross-sectional national survey was conducted in Japan for 963 eyes with bullous keratopathy between 1999 and 2001 by members of the Japan Cornea Society. Demographic characteristics, type of surgery, complications, and postoperative outcomes were analyzed. Bullous keratopathy accounted for 24.2% (963 eyes) of total keratoplasties performed during the period (Shimazaki et al., 2007).

Key Takeaways:

  • Global bullous keratopathy market likely to reach US$ 650 Million by 2033
  • North America is expected to hold highest market share during the forecast period.
  • Europe Bullous keratopathy market accounted for a 19.1% business share in 2022.
  • The amniotic membrane transplantation is an effective method of treatment for bullous keratopathy and has beneficial influence on the process of corneal healing and the improvement of visual acuity and diminish subjective symptoms.
  • By end-user, hospital segment dominated the market with revenue share of US$ 150 Million.

“With major breakthroughs in ophthalmology becoming evident, the scope for bullous keratopathy is expected to rise significantly. Moreover, healthcare practitioners are gravitating towards more precise surgeries to improve patient outcomes,” remarks an analyst at FMI.

Competitive Landscape

Key players in the Bullous Keratopathy market are- Hoffmann-La Roche Ltd, Regeneron, Pharmaceuticals, Inc., Pfizer, Inc., Bayer AG, Cellusion, CRSTEurope, Barraquer Eye Hospital, Planchard Eye & Laser Center, Medscape. Some recent developments in bullous Keratopathy market are:

  • In September 2022: Celregen and Cellusion Inc. signed an exclusive license agreement for corneal endothelial cell regenerative therapy in Greater China.
  • In July 2022: Carl Zeiss Meditec and Precise Bio announced a partnership in the development and commercialization of tissue-based implants for ophthalmology

More Valuable Insights 

Future Market Insights, in its new offering, presents an unbiased analysis of the global Embolization Coils market, presenting historical analysis from 2017 to 2021 and forecast statistics for the period of 2022 to 2032.

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Key Segments Profiled in the Bullous Keratopathy Market Industry Survey

Bullous Keratopathy Market by Therapies:

  • Emmecell
    • Drug Description
    • Regulatory Milestones
    • Safety and Efficiency
    • Product Profile
  • Cellusion
    • Drug Description
    • Other Development Activities
    • Clinical Development
    • Safety and Efficiency
    • Product Profile

Bullous Keratopathy Market by End User:

  • Hospitals
  • Surgical Centers

Bullous Keratopathy Market by Treatment:

  • Medical Management
    • Lubricants
    • Steroids
    • Hyperosmotic agents
    • Anti- Glaucoma drugs
    • Antibiotics
    • Amniotic Membrane Grafting (AMG)
    • Annular Keratotomy
    • Anterior Stromal Puncture

Author By:

Sabyasachi Ghosh (Associate Vice President at Future Market Insights, Inc.) holds over 12 years of experience in the Healthcare, Medical Devices, and Pharmaceutical industries. His curious and analytical nature helped him shape his career as a researcher.

Identifying key challenges faced by clients and devising robust, hypothesis-based solutions to empower them with strategic decision-making capabilities come naturally to him. His primary expertise lies in areas such as Market Entry and Expansion Strategy, Feasibility Studies, Competitive Intelligence, and Strategic Transformation.

Holding a degree in Microbiology, Sabyasachi has authored numerous publications and has been cited in journals, including The Journal of mHealth, ITN Online, and Spinal Surgery News.

About Future Market Insights (FMI)

Future Market Insights, Inc. (ESOMAR certified, recipient of the Stevie Award, and a member of the Greater New York Chamber of Commerce) offers profound insights into the driving factors that are boosting demand in the market. FMI stands as the leading global provider of market intelligence, advisory services, consulting, and events for the Packaging, Food and Beverage, Consumer Technology, Healthcare, Industrial, and Chemicals markets. With a vast team of over 5000 analysts worldwide, FMI provides global, regional, and local expertise on diverse domains and industry trends across more than 110 countries.

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Last Updated: 21-Dec-2023