CD Genomics Expands DNA Methylation Analysis with NGS-BSP to Advance Epigenetic Research

CD Genomics, known for its advanced sequencing solutions, has launched NGS-BSP (Next Generation Sequencing-based Bisulfite Sequencing PCR) to support epigenetic research. This introduction advances the field by enabling detailed DNA methylation profiling with high precision and efficiency, impacting various scientific disciplines.

NGS-BSP is an innovative methylation analysis technology that combines bisulfite conversion with high-throughput sequencing. The process begins by treating DNA with sodium bisulfite, converting unmethylated cytosine residues to uracil while preserving methylated cytosines. In PCR amplification, uracils are read as thymine, and methylated cytosines remain as cytosine. This C-to-T conversion is sequenced, precisely mapping the methylation status at CpG sites with single-base resolution.

The effectiveness of NGS-BSP relies on its high conversion rates, generally exceeding 99%, and the use of specifically designed primers. This results in a considerable throughput increase over traditional bisulfite sequencing methods, allowing hundreds of samples to be analyzed simultaneously. The method is sensitive enough to detect methylation levels as low as 1%.

NGS-BSP plays a vital role across various scientific disciplines. In the field of molecular biology, it helps uncover methylation patterns within regulatory DNA elements. For developmental biology, it serves as a tool to monitor dynamic methylation changes across different species. Additionally, in environmental epigenetics, NGS-BSP is used to analyze how external factors impact methylation landscapes.

As sequencing technology and bioinformatics evolve, NGS-BSP consistently improves its ability to explore genomic regulatory networks and identify epigenetic markers. Its high-throughput ability and precision make it valuable in modern epigenetic research.

This technology is significant in applications beyond clinical diagnostics. It aids epigenetic studies by providing insights into gene regulation and chromatin dynamics, relevant to environmental biology and agricultural sciences. "NGS-BSP offers a reliable approach for methylation analysis, enhancing our comprehension of epigenetic modifications," said CD Genomics' chief expert. Its capability in handling large sample volumes makes it suitable for broad agricultural and environmental studies.

Looking to the future, CD Genomics remains dedicated to driving innovation in genomic technologies. The introduction of NGS-BSP underscores the company’s ongoing commitment to providing researchers with precise and reliable tools to investigate complex genetic and epigenetic landscapes. This advanced method not only broadens the horizons of DNA methylation research but also opens up new avenues for future exploration in the realm of epigenetics. By continually enhancing its technological offerings, CD Genomics aims to support scientific discovery and contribute to the deeper understanding of genetic mechanisms.

For researchers eager to delve deeper into the capabilities of NGS-BSP and its benefits for genomic studies, CD Genomics invites inquiries and engagements with their knowledgeable team. Whether you're considering utilizing this platform for particular research objectives or seeking professional guidance on incorporating NGS-BSP into your work, the CD Genomics website offers extensive resources and detailed insights to assist you.

About CD Genomics

CD Genomics is a leading organization specializing in genomics technology services, dedicated to providing top-quality sequencing and data analysis support for scientific and clinical research. The company employs advanced sequencing platforms and standardized protocols to offer a comprehensive range of technical services, including whole genome sequencing, targeted sequencing, and epigenetic analysis.

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Address: Shirley, NY 11967, USA

Email: contact@cd-genomics.com