Newron announces agreement with the European Investment Bank (EIB) to extend the near-term tranche repayment dates of its 2018 Finance Contract

Parties agreed to extend the maturity date of all outstanding tranches under the Finance Contract to June 28, 2028 

Amendments subject to execution of definitive agreements 

Milan, Italy, and Morristown, NJ, USA, March 19, 2026, 07:00 am CET – Newron Pharmaceuticals S.p.A. (“Newron”) (SIX: NWRN, XETRA: NP5), a biopharmaceutical company focused on the development of novel therapies for patients with diseases of the central and peripheral nervous system (CNS), today reported that EIB and Newron have agreed to amend certain terms of the 2018 Finance Contract and Options Rights Agreement, as previously amended in 2024.

In particular, the parties agreed to extend the maturity date of all outstanding tranches under the Finance Contract to June 28, 2028. The agreement contains further terms and conditions. The agreed amendments are subject to execution by the parties of definitive agreements. Details of the 2018 Finance Contract, as amended in 2024, can be found in Newron’s 2024 Annual Report, which is posted on the Company’s website here.

Roberto Galli, Newron’s CFO, commented: “We appreciate the support of the EIB in helping us align the contractual obligations of our loan agreement to the potential timing of certain upcoming significant value inflection points presented by our lead drug candidate evenamide, which is currently developed in the global pivotal ENIGMA-TRS Phase III program for the treatment of patients suffering from treatment-resistant schizophrenia.”

About Newron Pharmaceuticals

Newron (SIX: NWRN, XETRA: NP5) is a biopharmaceutical company focused on the development of innovative therapies for patients with diseases of the central and peripheral nervous system. Headquartered in Bresso near Milan, Italy, the Company has a strong track record of advancing neuroscience-based treatments from discovery to market. Newron’s lead compound, evenamide, is a first-in-class glutamate modulator and has the potential to be the first add-on therapy for treatment-resistant schizophrenia (TRS) and for poorly responding patients with schizophrenia. Evenamide is currently developed in the global pivotal ENIGMA-TRS Phase III development program. Clinical trial results to date demonstrate the benefits of this drug candidate in the TRS as well as poorly responding patient population, with significant improvements across key efficacy measures increasing over time, as well as a favorable safety profile, which is uncommon for available antipsychotic medications. Newron has signed development and commercialization agreements for evenamide with EA Pharma (a subsidiary of Eisai) for Japan and other Asian territories, as well as Myung In Pharm for South Korea. Newron’s first marketed product, Xadago®/safinamide has received marketing authorization for the treatment of Parkinson’s disease in the European Union, Switzerland, the UK, the USA, Australia, Canada, Latin America, Israel, the United Arab Emirates, Japan and South Korea. The product is commercialized by Newron’s partner Zambon, with Supernus Pharmaceuticals holding marketing rights in the U.S., and Meiji Seika responsible for development and commercialization in Japan and other key Asian territories. For more information, please visit: www.newron.com