Pharmaco - Articles

In the ever-evolving field of pharmaceutical research and development, staying abreast of the latest trends and advancements is paramount. This year, the pharmaceutical industry is marked by groundbreaking innovations, regulatory shifts and unprecedented challenges. From cutting-edge technologies to novel therapeutic approaches, pharmaceutical research, and pharmaceutical approvals in 2024 are redefining how we perceive health care.
In the ever-evolving field of pharmaceutical research and development, staying abreast of the latest trends and advancements is paramount. This year, the pharmaceutical industry is marked by groundbreaking innovations, regulatory shifts and unprecedented challenges. From cutting-edge technologies to novel therapeutic approaches, pharmaceutical research, and phar…

This year, the United States expects to tally more than two million new cancer diagnoses— a first-ever prediction— and more than 611,000 cancer-related deaths. While the death rate from cancer is going down, largely due to improvements in early diagnosis and healthy lifestyle changes, the problem is that fewer people aren’t dying of cancer; that’s because the more people who are diagnosed, statistically the more who will die.
This year, the United States expects to tally more than two million new cancer diagnoses— a first-ever prediction— and more than 611,000 cancer-related deaths. While the death rate from cancer is going down, largely due to improvements in early diagnosis and healthy lifestyle changes, the problem is that fewer people aren’t dying of cancer; that’s because the more peop…

Reviewing the findings of new research into the pharma industry’s evolving aspirations for AI and intelligent automation, ArisGlobal’s Emmanuel Belabe talks to PharmiWeb about how far companies have come with smart transformation of key Safety & Regulatory processes. The international study, of 80+ organisations, spanned every patient treatment process domain, from CROs to young biotechs.
Lucy Walters, PharmiWeb (LW): What stood out most for you in the ArisGlobal 2024 Industry Survey Report[1] findings? Emmanuel Belabe, ArisGlobal (EB): The gap between use and intention. Although 75%+ of surveyed organisations claim they already use some form of ‘advanced automation’ within their processes today - up 13% from 2022 and just 5% in 2020, only 8% have applied next-generation capabilities in “al…

From nurturing a positive work culture to empowering and developing your people for success, Pioneer Group sets out some top tips for building a high-performance team as a life science company.
When it comes to recruitment, the life sciences industry is undoubtedly highly competitive. With demand for skilled professionals often outpacing the supply, attracting (and retaining) qualified candidates with the right expertise can be a significant challenge for many life science companies. From nurturing a positive work culture to empowering and developing your people for success, Pioneer Group sets out some top tips for building a high-performance team as a life science company. Invest in Graduate Programmes Investing in graduate outreach can help to bridge the skills gap in life sciences, and…

Business operations across a range of industries are continuing to feel the impact of the Red Sea shipping crisis. According to research conducted by the British Chambers of Commerce*, 55 per cent of UK exporters and 53 per cent of manufacturers and business-to-consumer (B2C) firms, such as retailers, have faced disruption due to the ongoing conflict.
Business operations across a range of industries are continuing to feel the impact of the Red Sea shipping crisis. According to research conducted by the British Chambers of Commerce*, 55 per cent of UK exporters and 53 per cent of manufacturers and business-to-consumer (B2C) firms, such as retailers, have faced disruption due to the ongoing conflict. The attacks have disrupted global supply chains, forcing shipping companies to divert supplie…

Specialists from across Mtech Access look at each of ISPOR’s top 10 HEOR trends for 2024–2025. Jump in as our experts give their hot take on each trend, sharing their perspectives on the topics in these areas (get ready – it’s a jam-packed read!).
    Executive Summary Hayley Shoel and Abigail Beveridge, from our Medical Writing Team, outline what to expect from this paper in the below Executive Summary. In January 2024, ISPOR published their ‘2024–2025 Top HEOR Trends’ report, a horizon scanning publication that highlighted key trends affecting healthcare decision-making around the world. Since these trends resonate with our own research and activities here at Mtech Access, experts within our team have come together to share their perspectives on each of the t…

Life scientists investigate the structure, function, behaviour, interactions, and evolution of living organisms, from the smallest microorganisms to complex ecosystems. They aim to understand the principles and processes that govern life, including biological systems, organisms’ mechanisms, and the relationship between living organisms and their environment. Life science plays a crucial role in fields such as medicine, biotechnology, agriculture, environmental science, and conservation.
What is Life Science? Life science is a branch of science that focuses on the study of living organisms. It encompasses various disciplines such as genetics, zoology, botany, microbiology, ecology, biochemistry, and physiology. Life scientists investigate the structure, function, behaviour, interactions, and…

Embarking on a systematic literature review is a critical step in evidence synthesis, providing a foundation for robust decision-making in the healthcare landscape. As with most things, there are ways to cut corners on systematic reviews. Sometimes there are true efficiencies to be made. Yet, all compromises have consequences. In this article, we delve into 11 common problems that may arise when cost-cutting compromises the quality of your systematic literature review.
1. Choosing the wrong type of systematic review methodology Selecting the wrong type of methodology for your review can have profound implications. A robust, gold standard Cochrane methodology involves two reviewers at all stages of the review, to avoid bias in the identification and presentation of the evidence, and ensur…

Revenue in Australia’s pharmaceuticals market is projected to reach US$10.16bn in 2024, with the largest market being Oncology Drugs with a projected market volume of US$2.01bn. This revenue is expected to grow at an annual rate of 6.76% from 2024 to 2028, resulting in a market volume of US$13.20bn by 2028.
Revenue in Australia’s pharmaceuticals market is projected to reach US$10.16bn in 2024, with the largest market being Oncology Drugs with a projected market volume of US$2.01bn. This revenue is expected to grow at an annual rate of 6.76% from 2024 to 2028, resulting in a market volume of US$13.20bn by 2028. In this article, we round up 10 of the top pharmaceutical companies driving this growth in Australia, with the leading companies listed on the Australian Securities Exchange in 2023,…

Last week, the Systech team had the opportunity to attend Pharmapack 2024 in Paris, France. This event, attracting over 5,000 visitors and 300 exhibitors, is a pivotal trendsetter for the European pharmaceutical industry. This year, three key trends particularly stood out, each likely to significantly influence the future of pharmaceutical packaging.
Last week, the Systech team had the opportunity to attend Pharmapack 2024 in Paris, France. This event, attracting over 5,000 visitors and 300 exhibitors, is a pivotal trendsetter for the European pharmaceutical industry. This year, three key trends particularly stood out, each likely to significantly influence the future of pharmaceutical packaging. Combating Counterfeits Combating counterfeiting is high on the agenda this year. Counterfeit d…

The life science sector has seen a major amount of technological adoption in the past few years, prompted largely by the pandemic. As the industry progresses in 2024, it will remain dedicated to using technology to improve clinical trials, expand patient diversity, and strengthen drug safety systems. Several trends are likely to shape the pharmaceutical and clinical research industries this year.
The life science sector has seen a major amount of technological adoption in the past few years, prompted largely by the pandemic. As the industry progresses in 2024, it will remain dedicated to using technology to improve clinical trials, expand patient diversity, and strengthen drug safety systems. Several trends are likely to shape the pharmaceutical and clinical research industries this year: R…

CD73, also known as ecto-5′-nucleotidase, is a groundbreaking immunoinhibitory protein that assumes a pivotal role in tumor growth and metastasis. Its primary function revolves around converting extracellular ATP into immunosuppressive adenosine, working in tandem with CD39 within normal tissues to curtail excessive immune reactions. However, this mechanism is often hijacked by tumors, utilizing CD73 to foster an adenosinergic process that shields them from immune assaults.
Exploring the Structure and Function of CD73 The CD73 gene finds its home in the 6q14.3 region of human chromosome 6, encoding a protein comprised of 549 amino acid residues. CD73 functions as a glycosylphospholipase, residing on the cell membrane surface and engaging with the extracellular matrix through its extracellul…

On Thursday the 23 November 2023, the PDA Ireland Chapter hosted an event on Microbiology – The Key to Compliance with Annex 1 and Risk Based Regulations. This sold-out event was led by industry leaders, experts, regulators, and pharmaceutical company representatives and was attended by professionals from across Ireland as well as overseas. The latest revision of the Annex 1 came into force in August 2023 and remains a hot topic within the industry.
On Thursday the 23 November 2023, the PDA Ireland Chapter hosted an event on Microbiology – The Key to Compliance with Annex 1 and Risk Based Regulations. This sold-out event was led by industry leaders, experts, regulators, and pharmaceutical company representatives and was attended by professionals from across Ireland as well as overseas. The…

Life Sciences manufacturing has experienced a demanding year, with continued pressure to innovate, reduce costs and overcome global supply chain disruption through improved visibility and contingency planning. These will continue to be priorities over the coming year, which will also bring new challenges, outlined by REPHINE’s Dr. Eduard Cayón.
2023 has been a demanding year for Life Sciences manufacturing, with continued pressure to innovate, bring costs down and overcome very real global supply chain disruption through improved visibility and contingency planning. The most significant and serious pharma R&D projects are concentrated in the biotech space now. Although small-molecule developments are still a focus of investment, this once dominant field is becoming steadily less strateg…

Here, we’ve compiled a list of life science recognition and awareness days taking place in 2024.
Here, we’ve compiled a list of life science recognition and awareness days taking place in 2024. Read the full article on PharmiWeb.Jobs.

With the departure of the casual investors who flooded the market during the COVID-19 pandemic, the dust settling on the Inflation Reduction Act, and the tightening of pharma budgets, 2023 was ultimately a year of correction. Adequate reflection upon the past 12 months is not possible without first glancing slightly further back to 2020. The pandemic saw slowed rates of clinical trials, except for COVID-19 vaccines, and a deluge of investment in the race to create the vaccine.
With the departure of the casual investors who flooded the market during the COVID-19 pandemic, the dust settling on the Inflation Reduction Act, and the tightening of pharma budgets, 2023 was ultimately a year of correction. Adequate reflection upon the past 12 months is not possible without first glancing slightly f…

GPC3, with its full name Glypican-3, is a member of the heparan sulfate proteoglycan family and is connected to the cell surface through the glycosylphosphatidylinositol anchor on the cell membrane. The GPC3 gene was first detected in a rat epithelial cell line in 1988. In the human body, the GPC3 protein expressed by the GPC3 gene is significantly different in different developmental stages and different tissues, such as low expression or no expression in gastric cancer, breast cancer, ovarian cancer and other cancers, but often in hepatocellular carcinoma is overexpressed.
The Structure of GPC3 GPC3, or Glypican-3, is an oncofetal glycoprotein tethered to the cell membrane via a glycophosphatidylinositol (GPI) anchor[1-2]. Its core protein comprises 580 amino acids and weighs in at 70 k…

One of the most exciting changes in the pharmaceutical sector over the last 10 years has been a shift from chemically synthesised drugs to focus more on a biologics. While biologics have the potential to revolutionise treatment for millions of people dealing with conditions such as rheumatoid arthritis, diabetes, autoimmune diseases and certain cancers, there is a significant wrinkle that needs attending to: delivery.
One of the most exciting changes in the pharmaceutical sector over the last 10 years has been a shift from chemically synthesised drugs to focus more on a biologics. While biologics have the potential to revolutionise treatment for millions of people dealing with conditions such as rheumatoid arthritis, diabetes, autoimmune diseases and certain cancers, there is a significant…

Technological advancements, climate change, and geopolitical tensions have transformed the global manufacturing landscape in recent decades. Along the way, academics and industry experts have explored concepts such as Industry 4.0 which encompasses the industrial internet of things, and ‘smart’ manufacturing, to help define the multitude of ways in which technological innovation has changed manufacturing processes.
Technological advancements, climate change, and geopolitical tensions have transformed the global manufacturing landscape in recent decades. Along the way, academics and industry experts have explored concepts such as Industry 4.0 which encompasses the industrial internet of things, and ‘smart’ manufacturing, to help define the multitude of ways in which technological innovation…

In your journey toward mental well-being, understanding the intricate interplay between brain chemistry and mental health is vital. Psychopharmacology, the study of how drugs affect the mind, plays a pivotal role in the treatment of various mental disorders.
In your journey toward mental well-being, understanding the intricate interplay between brain chemistry and mental health is vital. Psychopharmacology, the study of how drugs affect the mind, plays a pivotal role in the treatment of various mental disorders. Understanding the Basics of Psychopharmacology At its core, psychopharmacology explores the effects of medications on the brain, aiming to rectify imbalances in neurotransmitters — the chemical messengers that facilitate communication between nerve cells.1 Through a comprehensive un…