Avascular Necrosis Market Proceeds To Witness Upward Trend Over Forecast Period 2027 | CMI
The Avascular Necrosis Market analysis report speaks about the growth rate till 2027 manufacturing process, Growth, key factors driving this market with sales, revenue, and price analysis of lead manufacturers, distributors, traders and dealers of Avascular Necrosis.
Coherent Market Insights always aims at offering their clients an in-depth analysis and the best research of the various market. The “Avascular Necrosis Market projected to develop with growing expansion prospects”. The Avascular Necrosis Market report presents a calculated opinion of the analyzed Avascular Necrosis Market data. It explains various opportunities dedicated to different industries, suppliers, organizations, and associations offering various products and services such as offering them precise guidance for their expansion in the competition for reliable services to consumers. The report provides detailed information on key competitors in the market and on emerging companies with significant market share based on demand, revenue, sales, high-quality product manufacturers, and service providers.
Avascular necrosis (AVN), even called as ischemic bone necrosis, or aseptic necrosis, or osteonecrosis, a disorder causing the bone cell death, owing to blood supply loss. Often it leads to joint surface’s collapse along with subsequent arthritis owing to joint surface that is irregular. Avascular necrosis impacts long bones’ ends (epiphysis) including upper humerus, femur, and ankle joint bones. Often it develops owing to several factors combined, such as genetic, metabolic, raised consumption of alcohol, smoking, among other diseases.
Generally, an X-ray is helpful in diagnosing the joint pain’s cause. However, MRI (magnetic resonance imaging) method is a most sensitive to diagnose avascular necrosis at early stages. Contrary to bone scans, computed/computerized tomography (CT) scans, and X-rays, MRI finds the chemical changes within bone marrow, showing avascular necrosis in the earliest stages.
Options for nonsurgical treatment of avascular necrosis including anti-inflammatory medication, crutches, and activity changes, could help in relieving slow progression and pain of disease. Surgical treatments are core decompression, total hip replacement, and cartilage and bone grafting. On the basis of cause, avascular necrosis could be classified into non-traumatic and traumatic avascular necrosis.
As per the 2010 report by Science Direct Journal, traumatic injures including ankle sprain, joint dislocation, and fracture are AVN’s most common causes, that might occur 8 hours post disruption within blood supply. Non-traumatic avascular necrosis usually occurs at young ages and the causes comprise chronic liver disease, decompression sickness, corticosteroids, fat embolism syndrome, gout, Gaucher disease, hyperlipidaemia, metabolic bone disease, hemoglobinopathy, systemic chemotherapy, alcoholism, and systemic lupus erythematosus, among others.
The prominent players in the Avascular Necrosis Market are Bone Therapeutics, Boehringer Ingelheim GmbH, Bayer AG, Enzo Biochem Inc., Ethicon Inc., Eli Lilly and Company, Grifols SA, Integra LifeSciences Corporation, K-Stemcell Co Ltd., Medtronic Plc, Merck KGaA, Pfizer Inc., Sanofi SA, Stryker Corporation, Wright Medical Group N.V., and Zimmer Biomet Holdings. Manufacturers are focusing on advancements in treatment technologies such as gene therapy and stem cell-based treatment for avascular necrosis.
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Rising consumption of alcohol and corticosteroid use is expected to propel the global avascular necrosis market growth over the forecast period. Excessive consumption of alcohol and high dose, long-term use of systemic corticosteroid, are avascular necrosis’ key risk factors. In 2015, as per the World Journal of Orthopedics, usually avascular necrosis affects people aged from 30 to 50 years. Moreover, as per the similar source, over 10,000 – 20,000 individuals are diagnosed with osteonecrosis, in the U.S., annually. As per the 2015 data from National Organization for Rare Disorders, corticosteroid use and alcohol consumption affects over 30 & 35% people having non-traumatic avascular necrosis, respectively globally.
Other conditions or risk factors regarding non-traumatic osteonecrosis are autoimmune disease, decompression disease (Caisson disease), cancer, Gaucher disease, HIV infection, pancreatitis, and blood disorder including sickle cell diseases. Some medical treatments such as chemotherapy and radiation therapy can also result in osteonecrosis. Furthermore, people who underwent organ transplant highly susceptible to osteonecrosis.
Advancements in technology for avascular necrosis therapies including Advanced Therapy Medicinal Products (ATMPs) is expected to fuel growth of the global avascular necrosis market over the forecast period. Advanced Therapy Medicinal Products are a group of innovative therapies comprising of gene therapies, somatic cell therapy, along with tissue-engineered products.
Main points in Avascular Necrosis Market Report Table of Content
Chapter 1 Industry Overview
1.3 Research Scope
1.4 Market Analysis by Regions
1.5 Global Avascular Necrosis Market Size Analysis from 2021 to 2027
11.6 COVID-19 Outbreak: Avascular Necrosis Industry Impact
Chapter 2 Global Avascular Necrosis Competition by Types, Applications, and Top Regions and Countries
2.1 Global Avascular Necrosis (Volume and Value) by Type
2.3 Global Avascular Necrosis (Volume and Value) by Regions
Chapter 3 Production Market Analysis
3.1 Global Production Market Analysis
3.2 Regional Production Market Analysis
Chapter 4 Global Avascular Necrosis Sales, Consumption, Export, Import by Regions (2016-2021)
Chapter 5 North America Avascular Necrosis Market Analysis
Chapter 6 East Asia Avascular Necrosis Market Analysis
Chapter 7 Europe Avascular Necrosis Market Analysis
Chapter 8 South Asia Avascular Necrosis Market Analysis
Chapter 9 Southeast Asia Avascular Necrosis Market Analysis
Chapter 10 Middle East Avascular Necrosis Market Analysis
Chapter 11 Africa Avascular Necrosis Market Analysis
Chapter 12 Oceania Avascular Necrosis Market Analysis
Chapter 13 South America Avascular Necrosis Market Analysis
Chapter 14 Company Profiles and Key Figures in Avascular Necrosis Business
Chapter 15 Global Avascular Necrosis Market Forecast (2021-2027)
Chapter 16 Conclusions
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